Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Showing 341-360 of 6,921 articles

[Current status and future perspectives of precision treatment for locally advanced rectal cancer].

The treatment paradigm for locally advanced rectal cancer is undergoing a fundamental transformation from the traditional fixed triad of "radiotherapy-surgery-chemotherapy" to a holistic eco-system centered on precision stratification and multidisciplinary collaboration. This review synthesizes the current landscape and future perspectives of this evolution across four key dimensions. First, in su...

Apr 18 2026 41978391

[Research progress in clinical pathology and molecular mechanisms of pancreatic adenosquamous carcinoma].

Pancreatic adenosquamous carcinoma (PASC) is a rare exocrine malignancy of the pancreas with an increasing incidence, histologically defined by the coexistence of adenocarcinoma and squamous carcinoma components. Current pathological diagnosis typically requires the squamous component to comprise at least 30% of the tumor. However, this threshold remains controversial given the unconfirmed indepen...

Apr 18 2026 41978418
Investigation of the use of urinary proteomics in the prediction of childhood asthma.

PURPOSE: Urinary proteomics may help us improve our understanding and classification of asthma. We sought to identify clusters of children based on ur...

Apr 17 2026 42001975
Macrophage polarization as a therapeutic target in lung diseases: From pathogenesis to precision intervention.

Macrophages serve as core effector cells of the innate immune system, exerting dual regulatory roles in pulmonary homeostasis maintenance and disease ...

Apr 17 2026 41999690
Spatial proteomics of tertiary lymphoid structures reveals correlation with immunotherapy response in Merkel cell carcinoma.

BACKGROUND: Tertiary lymphoid structures (TLS) are ectopic lymphoid formations within or around tumours. They are emerging as important predictors of ...

Apr 17 2026 41466351
Advances in HLA and Non-HLA Immune Profiling: Integrating Next-Generation Sequencing and Artificial Intelligence in Transplantation.

Understanding transplantation outcomes requires an integrated view of immunological, genetic, and clinical determinants that collectively shape graft ...

Apr 17 2026 41992881
DANCE: Deep Learning-Assisted Analysis of ProteiN Sequences Using Chaos Enhanced Kaleidoscopic Images.

Cancer is a complex disease characterized by uncontrolled cell growth and requires an accurate classification for effective treatment. T cell receptor...

Apr 17 2026 41995104
A Hybrid Approach for Differentiating Fibrotic Hypersensitivity Pneumonitis and Idiopathic Pulmonary Fibrosis: Deep Feature Extraction and Machine Learning.

In patients over 60 years of age who are male, non-smokers, and in whom no organic antigen is identified in the history, differentiating fibrotic hype...

Apr 17 2026 41998456
Bridging In Silico Design and Experimental Validation: Virtual Screening and In Vitro Assessment of Biomimetic Anticancer Peptides Inspired by Horseshoe Crab Hemolymph Proteins.

BACKGROUND: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality, necessitating the development of more selective and safer the...

Apr 16 2026 41999784
Nanotrap-AI Integration Enables Ultra-Sensitive Point-of-Care HIV Testing.

Early HIV detection using noninvasive samples remains challenging because oral fluid contains extremely low antibody levels and enzymatic inhibitors t...

Apr 16 2026 41987636
Tuberculosis Disease Severity Assessment Using Clinical Variables and Radiology Enabled by Artificial Intelligence.

BACKGROUND: Chest X-ray (CXR) can assess pulmonary tuberculosis (TB) severity and may guide duration of treatment. However, the optimal radiological m...

Apr 16 2026 41989328
Decoupling lactylation-associated metabolic remodelling in Asthma: Integrated multi-omics and machine learning identify RCC2 as a potential therapeutic target.

BACKGROUND: Aerobic glycolysis promotes lactate accumulation and histone lactylation (Kla), yet the cell-type-specific distribution of this axis and i...

Apr 15 2026 42000636
From pathogenesis to precision medicine in systemic lupus erythematosus: Emerging biomarkers and targeted interventions.

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease characterized by immune dysregulation, autoantibody production, and chron...

Apr 15 2026 42095089
Natural bioactive as modulators of airway inflammation and remodeling: mechanistic insights.

Airway diseases such as asthma, COPD, pulmonary fibrosis, and other inflammatory airway conditions remain a significant threat to global health. Tradi...

Apr 15 2026 42004167
Update on pleural mesothelioma.

PURPOSE OF REVIEW: Pleural mesothelioma remains a universally lethal cancer with a rising global burden. This underscores the need for pulmonologists ...

Apr 15 2026 41982104
Recent Advances in Analytical Techniques for Cancer Diagnostics and Therapeutics: Combining State-of-the-Art Technologies for Precision Oncology.

Cancer remains a leading global health challenge, necessitating continuous advancements in diagnostics and therapeutics to enhance patient outcomes. A...

Apr 15 2026 41983744
Machine learning-based multi-omic analysis identifies CEP55, DLGAP5, and EZH2 as regulated cell death biomarkers linked to immunotherapy resistance in hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) often exhibits limited responsiveness to immune checkpoint inhibitors (ICIs), largely due to an immunosuppressive tumor...

Apr 15 2026 41984188
Fact-Checking Large Language Model Responses to a Health Care Prompt: Comparative Study.

BACKGROUND: Large language models use machine learning to produce natural language. These models have a range of potential applications in health care...

Apr 15 2026 41985066
A deep learning-based digital biopsy for predicting early recurrence in gastric cancer.

Early postoperative recurrence is a major cause of treatment failure in patients with locally advanced gastric cancer (LAGC), yet current staging syst...

Apr 15 2026 41986314
Decoding immunotherapy response through computational modeling.

Immunotherapy has seen success in treating patients with cancer, but variable responses underscore the need for effective patient stratification and t...

Apr 15 2026 41986319
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