Latest AI and machine learning research in allergy & immunology for healthcare professionals.
The treatment paradigm for locally advanced rectal cancer is undergoing a fundamental transformation from the traditional fixed triad of "radiotherapy-surgery-chemotherapy" to a holistic eco-system centered on precision stratification and multidisciplinary collaboration. This review synthesizes the current landscape and future perspectives of this evolution across four key dimensions. First, in su...
Pancreatic adenosquamous carcinoma (PASC) is a rare exocrine malignancy of the pancreas with an increasing incidence, histologically defined by the coexistence of adenocarcinoma and squamous carcinoma components. Current pathological diagnosis typically requires the squamous component to comprise at least 30% of the tumor. However, this threshold remains controversial given the unconfirmed indepen...
PURPOSE: Urinary proteomics may help us improve our understanding and classification of asthma. We sought to identify clusters of children based on ur...
Macrophages serve as core effector cells of the innate immune system, exerting dual regulatory roles in pulmonary homeostasis maintenance and disease ...
BACKGROUND: Tertiary lymphoid structures (TLS) are ectopic lymphoid formations within or around tumours. They are emerging as important predictors of ...
Understanding transplantation outcomes requires an integrated view of immunological, genetic, and clinical determinants that collectively shape graft ...
Cancer is a complex disease characterized by uncontrolled cell growth and requires an accurate classification for effective treatment. T cell receptor...
In patients over 60Â years of age who are male, non-smokers, and in whom no organic antigen is identified in the history, differentiating fibrotic hype...
BACKGROUND: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality, necessitating the development of more selective and safer the...
Early HIV detection using noninvasive samples remains challenging because oral fluid contains extremely low antibody levels and enzymatic inhibitors t...
BACKGROUND: Chest X-ray (CXR) can assess pulmonary tuberculosis (TB) severity and may guide duration of treatment. However, the optimal radiological m...
BACKGROUND: Aerobic glycolysis promotes lactate accumulation and histone lactylation (Kla), yet the cell-type-specific distribution of this axis and i...
Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease characterized by immune dysregulation, autoantibody production, and chron...
Airway diseases such as asthma, COPD, pulmonary fibrosis, and other inflammatory airway conditions remain a significant threat to global health. Tradi...
PURPOSE OF REVIEW: Pleural mesothelioma remains a universally lethal cancer with a rising global burden. This underscores the need for pulmonologists ...
Cancer remains a leading global health challenge, necessitating continuous advancements in diagnostics and therapeutics to enhance patient outcomes. A...
Hepatocellular carcinoma (HCC) often exhibits limited responsiveness to immune checkpoint inhibitors (ICIs), largely due to an immunosuppressive tumor...
BACKGROUND: Large language models use machine learning to produce natural language. These models have a range of potential applications in health care...
Early postoperative recurrence is a major cause of treatment failure in patients with locally advanced gastric cancer (LAGC), yet current staging syst...
Immunotherapy has seen success in treating patients with cancer, but variable responses underscore the need for effective patient stratification and t...