Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Showing 501-520 of 6,930 articles

CXCL9 as a key feature for deep learning-based immune subtyping and prediction of immune checkpoint blockade response in triple-negative breast cancer.

BACKGROUND: Immune checkpoint blockade (ICB) therapy has provided a promising treatment option for patients with triple-negative breast cancer (TNBC). However, existing efficacy prediction strategies based on programmed death-ligand 1 (PD-L1) expression and Tumor Mutational Burden (TMB) have significant limitations, leading to inaccurate patient selection. METHODS: This study integrated multi-omic...

Feb 26 2026 41759266

Recent insights for fish allergens: novel processing techniques and detection technology.

Fish allergy is a common food-related allergic reaction that can lead to serious health issues and poses a significant challenge to global food safety. To facilitate a clear understanding of risk prevention and control for fish allergy, we provide a comprehensive overview of the mechanism underlying fish allergy and the properties of fish allergens, with a dedicated focus on innovative processing ...

Feb 26 2026 41748462
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy.

Cancer immunotherapy, which leverages the immune system to combat tumor cells, has made significant advancements in oncology treatment in recent years...

Feb 25 2026 41736575
Comprehensive assessment of postoperative metachronous liver metastasis risk in colon cancer based on inflammatory indicators: a multicenter prospective study.

OBJECTIVE: Insidiousness is a hallmark of metachronous liver metastasis. Owing to the absence of a comprehensive machine-learning model integrating sy...

Feb 25 2026 41738596
Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next-Generation Approaches.

Advances in immunotherapy, particularly with immune checkpoint inhibitors, have improved clinical outcomes in various cancer subtypes; however, resist...

Feb 25 2026 41740058
Ultrasound-Responsive Serotonylation and Hallmark Pathway Gene Signatures Reveal Tumor Microenvironment Vulnerabilities and Prognostic Subtypes in Colorectal Cancer.

BACKGROUND: Focused ultrasound, low-intensity focused ultrasound, and microbubble-enhanced sonoporation are examples of ultrasound-based cancer therap...

Feb 25 2026 41742646
Applied immunoinformatics in modern vaccine design: a comprehensive review of available computational tools.

The rapid evolution of computational biology has transformed vaccine design from a largely empirical process into a rational, data-driven discipline. ...

Feb 25 2026 41747335
A machine learning model integrating circulating Temra cell transcriptional profiles to predict immunotherapy efficacy.

BACKGROUND: While immunotherapy has transformed treatment paradigms for cancer, durable response rates remain below 30%. Currently available biomarker...

Feb 25 2026 41747737
Transcriptome Profiling of Peripheral Blood for Inflammatory Subtype Classification and Diagnostic Model Construction in Asthma.

OBJECTIVE: This study aimed to identify inflammatory subtypes of asthma using peripheral blood transcriptomics and to derive candidate biomarkers supp...

Feb 24 2026 41732097
From guidelines to algorithms: the future of AI-augmented asthma care.

PURPOSE OF REVIEW: Artificial intelligence (AI) has emerged as an increasingly accessible and influential resource within both public and clinical dom...

Feb 24 2026 41733145
The rise of artificial intelligence in respiratory primary care and pulmonology: a scoping review.

Artificial intelligence (AI) is rapidly advancing respiratory disease management, from diagnosis to population lung health. This scoping review synthe...

Feb 24 2026 41730897
Breaking resistance in BRAF-mutant Melanoma: Novel strategies and biomarkers for optimizing targeted therapies.

In metastatic melanoma with a BRAFV600 mutation, inhibitors of BRAF and MEK have improved survival. Resistance may be acquired through late genetic al...

Feb 23 2026 41740779
Integrating B-mode ultrasound radiomics and clinical variables to predict 26-week progression-free survival in advanced hepatocellular carcinoma under targeted immunotherapy.

BACKGROUND: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality globally, with over 905,700 new cases and 830,200 de...

Feb 23 2026 41729219
ChatGPT Health performance in a structured test of triage recommendations.

ChatGPT Health launched in January 2026 as OpenAI's consumer health tool, reaching millions of users. Here, we conducted a structured stress test of t...

Feb 23 2026 41731097
A review of ageing related biomarkers in breath.

The growing ageing population presents significant challenges for healthcare systems, particularly in monitoring age-related physiological decline. Ag...

Feb 21 2026 41730370
MAPping dynamic heterogeneity in supercooled glass-formers.

A central question in glass physics is whether dynamic heterogeneity of supercooled liquids can be inferred from static structure. Successful models b...

Feb 21 2026 41717966
Emerging trends and converging evidence in tumor evolution: A comprehensive review.

BACKGROUND: Tumor evolution is a spatiotemporal dynamic process orchestrated by the interplay of genetic mutations, epigenetic reprogramming, and bidi...

Feb 20 2026 41747370
Immunotherapy in Triple-Negative Breast Cancer: From Molecular Mechanisms to Precision Medicine-Overcoming Resistance and Optimizing Clinical Outcomes.

Triple-negative breast cancer (TNBC) is the most violent type of breast cancer, in which estrogen receptors (ER), progesterone receptors (PR), and hum...

Feb 20 2026 41724338
Identifying microbial protease allergens through protein language model-guided homology.

Emerging research links the gut, skin, and oral microbiomes to allergies, with serine proteases (SPs) identified as potential allergens. This study le...

Feb 20 2026 41722567
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