Latest AI and machine learning research in allergy & immunology for healthcare professionals.
RATIONALE AND OBJECTIVES: The non-invasive biomarkers for predicting progression-free survival (PFS) in patients with hepatocellular carcinoma (HCC) treated with immunotherapy and molecular targeted therapy combined with transarterial chemoembolization (IMT-MTT-TACE) are urgently needed to identify individuals who are likely to benefit from this treatment regimen. This study aims to develop a non-...
Air pollution (AP), intensified by industrialization and urbanization, is a key environmental factor linked to rheumatoid arthritis (RA). However, its molecular and immunological impact on RA remains unclear. This study integrates epidemiological data, bioinformatics, single-cell transcriptomics, and animal models to investigate how AP contributes to the development of RA. Global epidemiological a...
Exosomes, nano-sized extracellular vesicles secreted by almost all cell types, have emerged as biologically compatible vehicles for targeted drug deli...
Chimeric antigen receptor (CAR)-T cell immunotherapy shows significant success in hematologic malignancies. However, it faces critical challenges in s...
BACKGROUND: Current relevance of positive patch-test reactions guides management in allergic contact dermatitis (ACD), yet its clinical predictors and...
BACKGROUND: Leptomeningeal metastasis (LM) is a fatal complication of advanced cancer with limited therapeutic options and poor prognosis. Immune chec...
Esophageal squamous cell carcinoma (ESCC) lacks a standardized classification system, resulting in inconsistent clinical management and a suboptimal p...
The advent of immunotherapy and targeted therapy has revolutionized oncology treatment in recent years, marking a transformative shift toward precisio...
Lipid nanoparticle (LNP)-mRNA technology has profoundly transformed the biomedical landscape, establishing itself as a highly versatile and powerful p...
Monoclonal gammopathies span a continuum from monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) to overt...
The primary approach to the treatment of seasonal allergic diseases involves minimizing exposure to allergens and initiating early personalized therap...
G-protein-coupled receptors (GPCRs) are a diverse family of seven-transmembrane domain receptors that play pivotal roles in various physiological and ...
UNLABELLED: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is characterized by heightened inflammation and immune dysregulation,...
BACKGROUND: Current atopic dermatitis (AD) therapy selection does not account for molecular drivers of disease, contributing to inadequate disease con...
Infectious diseases remain a major global public health concern, demanding rapid and accurate identification of pathogens. Although conventional diagn...
Immune checkpoint blockade, particularly programmed cell death protein 1 inhibition, has redefined the management of classic Hodgkin lymphoma (cHL), a...
Chimeric antigen receptor natural killer (CAR-NK) cell therapy is an emerging cancer treatment offering advantages over CAR-T therapy, including reduc...
BACKGROUND: Endocrine-disrupting chemicals (EDCs) are common environmental pollutants that affect human health. These chemicals have been linked to th...
BACKGROUND: There is increasing interest in the use of artificial intelligence (AI) to assist with respiratory diagnosis and risk prediction. Fuzzy lo...
BACKGROUND: The response of resectable non-small cell lung cancer (NSCLC) to neoadjuvant immunotherapy is heterogeneous. Machine learning can integrat...