Allergy & Immunology

Comparison of Indocyanine Green Versus Isosulfan Blue in Melanoma Sentinel Node Biopsy.

BACKGROUND: Sentinel lymph node biopsy (SLNB) is the standard for staging melanoma. Traditional dual...

From phenotypes to trajectories: Machine learning in asthma beyond labels.

Constructing a corpus of hematologic pathology notes for the fine-tuning of BERT models for named entity recognition.

BACKGROUND: Microscopic, immunologic, and chemical testing play a major role in the diagnostic proce...

Clinical and immunological significance of FOXO1 as a biomarker of improved response to immune checkpoint plus tyrosine kinase inhibitor therapy in metastatic renal cell carcinoma.

BACKGROUND: Predicting response to immune checkpoint inhibitor plus tyrosine kinase inhibitor (IO+TK...

Integrated spatial transcriptomics and pan-cancer XGBoost modeling uncover spatial drivers of immune exclusion and predict immunotherapy response.

Immunotherapy has revolutionized cancer treatment, yet characterizing the spatial complexity of the ...

mRNA vaccines in cancer immunotherapy: current progress and perspectives in solid tumors and hematologic malignancies.

The unprecedented success of mRNA vaccines during the COVID-19 pandemic has accelerated the developm...

From prediction to precision: how immunopeptidomics advances neoantigen discovery.

T cell recognition of peptides presented by class I and II human leukocyte antigen (HLA) molecules i...

Integrating Bulk RNA-Seq and Spatial Transcriptomics Data to Reveal Distinct Immune Escape Mechanism and Immunotherapy Based on Post-Translational Modification in Head and Neck Squamous Cell Carcinoma.

Post-translational modification (PTM) plays a crucial role in head and neck squamous cell carcinoma ...

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action.

Vagus nerve stimulation (VNS) is an established neuromodulatory therapy approved for epilepsy, depre...

Models Integrating Disease Heterogeneity and MPA Exposure Predict Systemic and Renal Efficacy of Mycophenolate in Pediatric Lupus Nephritis.

OBJECTIVES: This study aimed to develop and validate integrated prediction models for pediatric lupu...

Adult patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still's disease.

Autoinflammation of unknown origin remains amongst the most enigmatic of systemic autoinflammatory d...

Short-chain fatty acid-producing microbes differentiate non-infectious and infectious neutropenic fever in leukemia.

UNLABELLED: Neutropenic fever (NF) is often the first sign of infection in patients with hematologic...

Animal Models of Allergen Immunotherapy for Allergic Airway Inflammation.

Allergen immunotherapy (AIT) is currently the only disease-modifying therapy for allergic airway inf...

Gene expression and machine learning techniques uncover corneal biomarkers associated with oxidative stress in the myopia progression.

This study aimed to identify and validate corneal biomarkers underlying myopia using human corneal t...

Neoantigen Targeting as a Novel Approach for Therapy-Resistant Tumors.

Neoantigens have emerged as central targets in the development of individualized cancer vaccines, as...

Virtual cell/virtual cell like: The key to unlocking a new era of HIV/AIDS treatment ?

Virtual Cell (VC) technology, as an interdisciplinary frontier at the intersection of systems biolog...

Nanoparticle-based immunotherapeutic strategies to overcome cancer drug resistance: From biological barriers to artificial intelligence-driven design.

Although cancer immunotherapy has revolutionized oncology, its clinical efficacy remains substantial...

AI-driven body composition atlas reveals its association with NSCLC immunotherapy outcome and molecular background: a multicenter study.

Although previous studies have linked body composition to immunotherapy efficacy, comprehensive mult...

Benchmarking Hybrid CNN-Transformer Versus Pure Transformer Architectures for Accelerated Hyperpolarized 129Xe MRI Reconstruction.

BACKGROUND: Hyperpolarized 129Xe MRI faces technical challenges including low signal-to-noise ratio ...

Identification of MHC ligands through allele-guided isolation combined with machine learning for improved MHC assignment using ARDisplay-I.

The isolation of MHC ligands and subsequent analysis by mass spectrometry is considered the gold sta...

Etiologic diagnosis of seasonal allergic rhinitis supported by artificial intelligence: the @IT-2020 project.

BACKGROUND: A precise etiological diagnosis of seasonal allergic rhinitis (SAR) is essential for a t...