Latest AI and machine learning research in allergy & immunology for healthcare professionals.
PURPOSE: Endoscopically identifying eosinophilic esophagitis (EoE) is difficult due to its rare incidence and subtle morphology. We aimed to develop a robust and accurate convolutional neural network (CNN) model for EoE identification and classification in endoscopic images. MATERIALS AND METHODS: We collected 548 endoscopic images from 81 patients with EoE and 297 images from 37 normal patients. ...
The discovery of natural killer (NK) cells stands among the fundamental milestones in modern immunology. To mark the 50-year anniversary of the first publications on NK cells in 1975, a symposium was held at Karolinska Institutet in Stockholm, Sweden, on October 14, 2025. The symposium brought together scientists from across generations to reflect on the field's historical roots and future directi...
Purpose To evaluate the predictive value of myosteatosis as an opportunistic finding in coronary artery calcium (CAC) CT scans for clinically diagnose...
PURPOSE: Missing information is common in real-world claims data, particularly on behavioral confounders, for example, smoking. Often one category of ...
OBJECTIVES: Detection of antinuclear antibody (ANA) via indirect immunofluorescence (IIF) on HEp-2 cells is a screening test for the serological diagn...
Recent advancements in cancer immunotherapy have transformed clinical oncology, with monoclonal antibodies (mAbs), immune checkpoint inhibitors, adopt...
INTRODUCTION: Proton pump inhibitors (PPIs) are widely used to treat acid-related disorders; however, treatment response varies significantly due to C...
Identifying conserved, immunogenic proteins that confer protection against Streptococcus pneumoniae (pneumococcus) colonization could enable developme...
Artificial intelligence (AI) is increasingly transforming health care, particularly in solid organ transplantation, where it addresses complex challen...
BACKGROUND: Pharmacotyping, the ex vivo measurement of tumor cell responses to drugs, is particularly important for cancers lacking actionable genomic...
BACKGROUND: Hymenoptera venom immunotherapy is an established treatment for severe allergic reactions, aiming to modulate the immune response and redu...
In contrast to the MSI-H subtype, most microsatellite-stable (MSS) colorectal cancer (CRC) patients exhibit poor prognosis and limited responsiveness ...
Lung adenocarcinoma (LUAD) displays significant morphological and molecular heterogeneity both within and between tumors. This heterogeneity, coupled ...
BACKGROUND: Primary immunodeficiencies (PIDs) are rare disorders caused by immune system defects that are commonly screened using multi-parameter flow...
A Whole Slide Image (WSI) is a high-resolution digital image created by scanning an entire glass slide containing a biological specimen, such as tissu...
Recent innovations in skin microphysiological systems (MPSs) have gained momentum following regulatory advances such as the FDA Modernization Act 2.0 ...
Circulating cell-free DNA (cfDNA) has firmly established itself as a cornerstone of liquid biopsy, advancing the noninvasive diagnosis and monitoring ...
Aging and age-related diseases are a major public health concern, driving interest in anti-aging research. While small molecules and natural compounds...
Immunotherapy, a therapeutic strategy aimed at modulating the host immune system, has undergone rapid evolution over recent decades, particularly in o...
Mushrooms are rich in structurally diverse bioactive compounds that exert potent immunomodulatory effects, making them promising candidates for next-g...