Latest AI and machine learning research in allergy & immunology for healthcare professionals.
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with diverse clinical phenotypes. Although a variety of drugs are available, the current clinical treatment still cannot meet the needs of patients with AD. In this study, we designed a series of polypeptides through a new drug discovery technology combined with big data and artificial intelligence in our polypeptide library and ...
Acylation modification plays a crucial role in modulating head and neck squamous cell carcinoma (HNSCC) progression, and their specific prognostic implications in HNSCC have not been thoroughly investigated. Eleven acylation modifications (AM) (crotonylation, lactylation, succinylation, benzoylation, butyrylation, malonylation, glutarylation, 2-hydroxyisobutyrylation, β-hydroxybutyrylation, palmit...
BACKGROUND: Despite antiretroviral therapy (ART), 10-40 % of people living with HIV (PLWH) fail to normalize CD4+ T cells, known as immune non-respond...
A robust predictive biomarker is critical for identifying patients with NSCLC who may benefit from immunotherapy. This study developed a CT-based habi...
PURPOSE OF REVIEW: The purpose of this study is to describe why this review is timely and relevant. Endotyping, the organization of rhinologic inflamm...
BACKGROUND: Asthma is the most common chronic disease in children. Suboptimal asthma control is prevalent and causes significant health care costs. El...
OBJECTIVE: To identify the most influential features of asthma control in children and to assess whether feature selection improves model performance....
Self-diagnosis-the capacity of a system to detect and correct its own failures-is a defining property of adaptive systems. In the brain, recursive sel...
BACKGROUND: Smooth muscle (SM) invasion represents a critical feature of prostate cancer (PCa) progression and metastasis. This study aimed to develop...
Lung sound analysis is critical for diagnosing respiratory diseases such as asthma, bronchiectasis, bronchiolitis, COPD, LRTI, pneumonia, and URTI. Tr...
BACKGROUND: The peripheral blood film (PBF) analysis traditionally relies on manual microscopy (MM), a labour-intensive method with inter-observer var...
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a dense stroma and dysfunctional vasculature, limiting drug delivery and immune infiltrati...
PURPOSE: To evaluate the measurement variability and reproducibility of prone imaging with quantitative computed tomography (QCT) compared with supine...
Immune checkpoint inhibitors have partially improved treatment outcomes for patients with head and neck squamous cell carcinoma (HNSCC), but the respo...
Vaccination is an effective approach that saves the lives of millions of people. Computer tools and technologies have recently helped design novel, sa...
The tumor immune microenvironment (TIME) critically impacts cancer progression and immunotherapy response. Multiplex immunofluorescence (mIF) is a pow...
With the advent of novel cancer treatment options such as immunotherapy, studying the tumour immune micro-environment (TIME) is crucial to inform on p...
Electronic nose is an emergent technique for noninvasive disease detection via breath analysis, which is, however limited by the sensitivity and selec...
PURPOSE OF REVIEW: Immediate hypersensitivity disorders, such as asthma, food intolerance, and anaphylaxis, have risen dramatically since the 20th cen...