Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Showing 721-740 of 6,930 articles

Identification of uridine phosphatase 1 as a potential therapeutic target in gastric cancer by integrated bioinformatics analysis and experimental validation.

Gastric cancer remains a major global health challenge, and its early diagnosis and prognosis prediction pose significant challenges to the current clinical treatment of gastric cancer. Finding gastric cancer biomarkers is essential to comprehending its pathophysiology and creating novel targeted treatments. Following the acquisition and processing of the gastric cancer sample, the single-cell RNA...

Aug 26 2025 40855937

Identification of key genes in intracranial aneurysm via WGCNA: insights into immune microenvironment and therapeutic targets.

BACKGROUND: Intracranial aneurysms (IA) are prevalent vascular lesions whose rupture causes subarachnoid hemorrhage with high disability and mortality. Although cell adhesion molecules help maintain vascular integrity, their roles in IA pathogenesis remain incompletely defined. High-throughput bioinformatics offers a means to elucidate these mechanisms. METHODS: Transcriptomic datasets of IA tissu...

Aug 25 2025 40851533
Convergence: Multi-omics and AI are reshaping the landscape biomedical research.

This special volume of Biochimica et Biophysica Acta - Molecular Basis of Disease showcases a transformative era in biomedical research, driven by the...

Aug 25 2025 40865690
LYnet: Computational identification of tumor T cell antigens using convolutional and recurrent neural networks.

BACKGROUND: Immunotherapy represents a paradigm shift in oncology, offering advantages in efficacy and specificity over traditional therapies. Key to ...

Aug 19 2025 40876398
Function of chemokines in embryo implantation.

Embryo implantation centrally involves the maternal immune system's specific acceptance of the semi-allogeneic embryo. Despite advances in assisted re...

Aug 5 2025 40769846
Selenium biofortification: integrating one health and sustainability.

Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivi...

Aug 2 2025 40751944
A machine learning-driven transcriptomic study reveals the key role of Romo1 in reversing central sensitization through stellate ganglion block in migraine: An interventional study based on a recurrent migraine rat model.

OBJECTIVES/BACKGROUND: This study utilized a nitroglycerin (NTG)-induced chronic migraine rat model to explore the therapeutic effects and underlying ...

Aug 1 2025 40747904
A machine learning platform for genotype-specific cardiotoxicity risk prediction using patient-derived iPSC-CMs.

INTRODUCTION: Drug-induced Torsades de Pointes (TdP) has led to withdrawal of several drugs from the market. Individuals with inherited cardiac channe...

Jul 22 2025 40706985
Artificial intelligence in smartphone video analysis for equine asthma diagnostic support.

BACKGROUND: Equine asthma is a prevalent respiratory disease that negatively impacts horses' health and athletic performance. Traditional diagnostic m...

Jul 21 2025 40686060
AI Prognostication in Nonsmall Cell Lung Cancer: A Systematic Review.

The systematic literature review was performed on the use of artificial intelligence (AI) algorithms in nonsmall cell lung cancer (NSCLC) prognosticat...

Jul 18 2025 40679809
Can a Rule-Based Expert System Diagnose Nasal Obstruction from Nasoendoscopy Videos?

Nasal obstruction has multiple causes requiring specialist endoscopy for diagnosis. A rule-based expert system (RB-ES), which applies five "if-then" r...

Jul 16 2025 40669854
Tuning antibody stability and function by rational designs of framework mutations.

Artificial intelligence and machine learning models have been developed to engineer antibodies for specific recognition of antigens. These approaches,...

Jul 13 2025 40653772
iALP: Identification of Allergenic Proteins Based on Large Language Model and Gate Linear Unit.

The rising incidence of allergic disorders has emerged as a pressing public health issue worldwide, underscoring the need for intensified research and...

Jul 13 2025 40652417
Integrative analysis of multi-omics data and gut microbiota composition reveals prognostic subtypes and predicts immunotherapy response in colorectal cancer using machine learning.

Colorectal cancer (CRC) exhibits substantial heterogeneity in molecular subtypes and clinical outcomes. We performed an integrative analysis of multi-...

Jul 12 2025 40652009
Development and validation of a prognostic model for predicting survival and immunotherapy benefits in melanoma based on metabolism-relevant genes.

Skin cutaneous melanoma (SKCM) is a fatal form of skin cancer. Metabolism-related genes (MRGs) comprise a group of genes that possess the ability to m...

Jul 12 2025 40652057
Artificial Intelligence Performance in Pediatric Asthma.

OBJECTIVE: Asthma is the most common chronic disease of childhood, characterized by symptoms such as wheezing, shortness of breath, and coughing. With...

Jul 11 2025 40643318
Comprehensive multi-omics and machine learning framework for glioma subtyping and precision therapeutics.

Glioma is a highly heterogeneous and aggressive brain tumour that demands an integrated understanding of its molecular and immunological landscape. We...

Jul 10 2025 40640380
Automated detection of air trapping from mechanical ventilation waveform through interpretable dual-channel 1D convolutional neural network.

. Air trapping is a major symptom of respiratory diseases like chronic obstructive pulmonary disease and asthma, and has always been a significant pro...

Jul 10 2025 40588005
Single-cell spatial transcriptomics reveals immunotherapy-driven bone marrow niche remodeling in AML.

Given the graft-versus-leukemia effect observed with allogeneic hematopoietic stem cell transplantation in refractory or relapsed acute myeloid leukem...

Jul 9 2025 40632867
Computation strategies and clinical applications in neoantigen discovery towards precision cancer immunotherapy.

Neoantigens, which are tumor-specific peptides generated by malignant cells, can be presented to T cells to elicit immune responses. Owing to their tu...

Jul 9 2025 40629481
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