Latest AI and machine learning research in allergy & immunology for healthcare professionals.
BACKGROUND: Osteoarthritis (OA) is a chronic degenerative joint disease characterized by the progressive deterioration of articular cartilage, significantly impacting the quality of life in middle-aged and elderly populations. The Ras and Hippo signaling pathways play critical roles in regulating cell proliferation, differentiation, and stress responses; however, their interactive mechanisms in OA...
PURPOSE: Antibody-drug conjugates (ADC) targeting trophoblast cell surface antigen 2 (TROP-2) and cMET are entering clinical trials in non-small cell lung cancer (NSCLC). Their translation depends on reliable biomarker assessment, a task still dominated by subjective visual scoring and inconsistent reproducibility. EXPERIMENTAL DESIGN: We built a modular Artificial Intelligence (AI) pipeline that ...
Asthma is a chronic inflammatory airway disease characterized by barrier dysfunction and excessive inflammatory response. In this study, we identified...
Myeloid cells-including macrophages, monocytes, neutrophils and dendritic cells-are metabolically plastic sentinels that shape the tumor microenvironm...
BACKGROUND: ∼60%-70% of patients with metastatic non-small cell lung cancer (NSCLC) have relatively low tumor mutational burden (TMB), with limited bi...
BACKGROUND: Patch testing, the gold standard for allergic contact dermatitis (ACD) diagnosis, suffers from inter-observer variability. We developed a ...
PURPOSE OF REVIEW: The review examines the application of machine learning (ML) and large language models (LLMs) to asthma management. We sought to id...
Chloroplastic proteins play pivotal roles in optimizing photosynthesis, particularly under fluctuating environmental conditions. Ribulose-1,5-bisphosp...
BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is an aggressive tumor with high metastatic potential and therapeutic resistance, yet the role of ...
Endometrial cancer (EC) is the most common gynaecological malignancy worldwide, yet the prognosis for advanced and recurrent disease remains poor, hig...
OBJECTIVES: This study aimed to use machine learning to explore Behçet's syndrome (BS) heterogeneity by integrating immunocyte subpopulations and clin...
Malignant tumors, including osteosarcoma (OS), are major non-communicable chronic diseases driven by systemic inflammation and oxidative stress. While...
Trypanosomatids, including the genera Trypanosoma and Leishmania, are protozoan parasites of significant medical and veterinary relevance. These organ...
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a five-year survival rate below 10%. Regulatory cell death (RCD) plays ...
Neoantigens are critical targets for cancer immunotherapy, yet the relationship between experimentally validated neoantigen burden and antigen process...
BACKGROUND: Artificial intelligence (AI) is emerging as a critical tool for nurse practitioners delivering pediatric and adolescent and young adult (A...
BACKGROUND: Disulfidptosis is a novel form of glucose starvation-induced cell death, yet its prognostic implications in gastric cancer (GC) remain lar...
PURPOSE: Non-small cell lung cancer (NSCLC) remains a major clinical challenge, with Programmed death-ligand 1 (PD-L1) expression serving as a crucial...
BACKGROUND: The indoor environment has been implicated as a critical factor in the development of allergic diseases. However, the interplay among indo...
OBJECTIVE: Glioblastoma (GBM) is the most aggressive type of intracranial malignant tumor, known for its extremely poor prognosis. Lactylation, a newl...