Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Showing 101-120 of 6,921 articles

OpenIO: An open framework for AI-native immunotherapy.

We propose Open Immune Oncology (OpenIO), a framework integrating generative AI and omics to advance precision oncology. By leveraging biological scaling laws and foundation models, we aim to transition immunotherapy from empirical screening to rational, AI-native engineering of therapeutic interventions.

Jun 25 2026 42349428

Deciphering Allergen Peptides for Dermatological and Cosmetic Applications with Explainable Artificial Intelligence.

This study explores the potential of explainable artificial intelligence to advance our understanding of allergen peptides in the context of dermatology and cosmetics. We present a hybrid deep learning framework that integrates Temporal Convolutional Networks (TCN) and stacked Long Short-Term Memory (LSTM) architectures, enhanced with Evolutionary Scale Modeling (ESM) embeddings, to decode allerge...

Jun 25 2026 42345568
Benzo(a)pyrene aggregating lung inflammation via inducing IL1R1 expression in asthma: Insights from network toxicology, single-cell transcriptomics, and Mendelian randomization.

OBJECTIVE: Exposure to benzo(a)pyrene (BaP) negatively affects lung inflammation in patients with asthma. However, there is a lack of systematic resea...

Jun 25 2026 42349175
Generative Artificial Intelligence and Prompt Engineering in Asthma-Related Settings.

Generative artificial intelligence (AI) is rapidly emerging as a valuable tool in medicine, with increasing use in asthma and allergy practice. Large ...

Jun 25 2026 42349677
The development of a computational model for predicting sensitization potential in cosmetics.

The analysis and testing allergenic ingredients in cosmetics are crucial for quality and safety control. This study presents an improved method based ...

Jun 25 2026 42349865
A prediction model based on tumor immune microenvironment for immunotherapy response in gastric cancer.

This study aimed to develop a robust prediction model- using machine-learning algorithms based on the core indicators of the tumor immune microenviron...

Jun 25 2026 42350633
Dynamic gut microbiota shift in chronic liver disease progression: machine learning models and the E/Er ratio as a predictive biomarker.

BACKGROUND: Chronic liver disease (CLD) and its progression to compensated cirrhosis (CC), decompensated cirrhosis (DC), and acute-on-chronic liver fa...

Jun 25 2026 42351186
Identification of T-cell exhaustion-related biomarkers in aortic dissection via integrated multi-omics analysis and mendelian randomization.

BACKGROUND: Aortic dissection (AD) is a life-threatening cardiovascular emergency characterized by high acute mortality. While immune dysregulation is...

Jun 25 2026 42351206
Bridging the rural logistics penalty: quantifying structural costs and designing policy mechanisms for home TCM delivery to older adults with chronic respiratory diseases.

BACKGROUND: Equitable access to prescribed therapies remains challenging for older adults with chronic respiratory diseases (CRDs) in rural China. Liq...

Jun 24 2026 42343367
Molecular characteristics and modifications of glioblastoma affecting the efficacy of immunotherapy.

Glioblastoma is a highly aggressive brain tumor characterized by complex genetic, molecular, and epigenetic features that present significant challeng...

Jun 24 2026 42341896
An immunological panacea for cancer-related cachexia.

Cancer cachexia, responsible for up to 30% of cancer deaths, has transitioned conceptually from a mere nutritional deficit into a highly coordinated, ...

Jun 24 2026 42342529
Cough biomarkers for diagnosis and monitoring of respiratory disease: a systematic review.

Cough is a common and physiologically informative component of respiratory morbidity, but its potential for diagnosing and monitoring disease is not t...

Jun 24 2026 42342266
Screening of atherosclerosis diagnostic markers based on lymphangiogenesis-related genes and analysis of immunological characteristics.

BACKGROUND: Atherosclerosis (AS) was a major cause of cardiovascular disease, and traditional diagnostic methods often fail to detect AS promptly and ...

Jun 23 2026 42337638
Machine learning-based integration develops a novel lysosome-related prognostic signature associated with prognosis and immune infiltration landscape in acute myeloid leukemia.

BACKGROUND: Lysosomes are essential for intracellular degradation and recycling, and changes in their function significantly contribute to tumor growt...

Jun 23 2026 42334654
A Two-Stage, Semi-Supervised Deep Learning Framework for the Detection and Classification of Ambient Pollen using Evanescent Wave Scattering.

Airborne pollen, an aeroallergen, impacts human health, particularly as climate change shifts pollen dynamics, requiring accurate monitoring to suppor...

Jun 23 2026 42337390
Quality of AI chatbot-generated information on hypersensitivity pneumonitis for clinical and patient use.

BACKGROUND AND AIM: Hypersensitivity pneumonitis (HP) is a complex, immüne mediated interstitial lung disease in which accurate diagnosis and long ter...

Jun 22 2026 42329012
From in silico screening to mechanism: computational advances in developing anti-allergic agents for food allergy.

Food allergy represents a significant global health concern with considerable socioeconomic impacts. While natural bioactive components offer promisin...

Jun 22 2026 42330160
PCT-Anchored Machine Learning for Pre-Culture Identification of Gram-Negative Sepsis in Children: A Four-Site Study.

OBJECTIVE: Procalcitonin (PCT) has moderate accuracy for bacteremia detection but is infrequently used in pediatric emergency departments, partly due ...

Jun 22 2026 42320014
Scenario-based multi-parametric QC for quality control of complex algorithms used in clinical care.

Complex algorithms and prediction models are increasingly being developed, investigated and applied for clinical use in medical laboratories and beyon...

Jun 22 2026 42321983
Expression of the High Affinity Neurotensin Receptor Defines an Immune‑cold, Poor‑prognosis Colorectal Cancer Subtype.

OBJECTIVE: We investigated neurotensin receptor 1 (NTSR1) as a potential mediator of the mechanical immune barrier that contributes to T-cell exclusio...

Jun 22 2026 42322125
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