Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Showing 148-168 of 5,393 articles
Disulfide bond-related gene signature development for bladder cancer prognosis prediction and immune microenvironment characterization.

Bladder cancer is the fourth most common malignant tumor in men, with limited therapeutic biomarkers...

Immunological biomarkers and gene signatures predictive of radiotherapy resistance in non-small cell lung cancer.

INTRODUCTION: A significant challenge in treating non-small cell lung cancer (NSCLC) is its inherent...

Unbiased Quantification of Persistent Postural and Motor Deficits Following Spinal Cord Injury in Mice.

Spinal cord injury (SCI) causes multifaceted postural and motor impairments that are challenging to ...

Biophysical modeling for accurate T cell specificity prediction of viral and tumor antigens.

Accurate predictions of T cell receptor (TCR) specificity remain an important open problem in immuno...

Immunotyping the Tumor Microenvironment Reveals Molecular Heterogeneity for Personalized Immunotherapy in Cancer.

The tumor microenvironment (TME) significantly influences cancer prognosis and therapeutic outcomes,...

Comparative Evaluation of ChatGPT and ChatGLM Performance in Response to Common Queries on Pediatric Atopic Dermatitis.

BACKGROUND: Atopic dermatitis (AD) is a prevalent chronic and recurrent skin condition in children. ...

Factors Influencing the Binding of HIV-1 Protease Inhibitors: Insights from Machine Learning Models.

HIV-1 protease inhibitors are crucial for antiviral therapies targeting acquired immunodeficiency sy...

Baseline Radiomics as a Prognostic Tool for Clinical Benefit from Immune Checkpoint Inhibition in Inoperable NSCLC Without Activating Mutations.

Checkpoint inhibitors (ICIs) are key therapies for NSCLC, but current selection criteria, such as e...

[Current status and trends of perioperative immunotherapy for gastric cancer].

In recent years,immunotherapy,particularly immune checkpoint inhibitors,has been widely used in the ...

Immunogenic cell death biomarkers for sepsis diagnosis and mechanism via integrated bioinformatics.

Immunogenic cell death (ICD) has been implicated in sepsis, a condition with high mortality, through...

High Throughput Meta-analysis of Antimicrobial Peptides for Characterizing Class Specific Therapeutic Candidates: An In Silico Approach.

The increasing incidence of antimicrobial resistance is becoming a serious concern worldwide and req...

High-fidelity in silico generation and augmentation of TCR repertoire data using generative adversarial networks.

Engineered T-cell receptor (eTCR) systems rely on accurately generated T-cell receptor (TCR) sequenc...

The development of predictive biomarkers and immunologic markers for breast cancer: current status and future perspectives.

Breast cancer is the leading cause of cancer-related mortality among women worldwide. The developmen...

Oral ENPP1 inhibitor designed using generative AI as next generation STING modulator for solid tumors.

Despite the STING-type-I interferon pathway playing a key role in effective anti-tumor immunity, the...

Single-cell multimodal analysis reveals tumor microenvironment predictive of treatment response in non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) constitutes over 80% of lung cancer cases and remains a leading c...

Construction and Multi-dimensional Validation of a Lactylation-Related Signature for Glioblastoma Multiforme Prognostic and Therapeutic Purposes.

Glioblastoma multiforme, one of the most malignant types of brain tumor, heavily relies on glycolyti...

Single-cell and bulk transcriptome analyses reveal elevated amino acid metabolism promoting tumor-directed immune evasion in colorectal cancer.

INTRODUCTION: Colorectal cancer (CRC), the third most common cancer worldwide, often shows limited r...

Immunopeptidomics-guided discovery and characterization of neoantigens for personalized cancer immunotherapy.

Neoantigens have emerged as ideal targets for personalized cancer immunotherapy. We depict the pan-c...

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