Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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From Tasks to Topology: Dorsal and Ventral Streams Emerge in Optimized Neural Networks

The primate visual system is organized into dorsal and ventral pathways, classically linked to visuo...

Targeting peptide–MHC complexes with designed T cell receptors and antibodies

Class I major histocompatibility complexes (MHCs), expressed on the surface of all nucleated cells, ...

Self-supervised AI reveals a lethal discohesive phenotype in lung adenocarcinoma

Applications of artificial intelligence (AI) to histopathology are now common, but most require supe...

A transcription factor-responsive enhancer discovery platform for targeted immunotherapy

Synthetic enhancers with high specificity are crucial for therapeutic gene control. Although existin...

DPCMHC: efficient prediction of MHC-peptide binding affinity by deep learning based on dual-padding convolution

Predicting peptide binding affinities to major histocompatibility complex class I (MHCI) is a crucia...

ROSIE-Enabled Spatial Mapping Reveals Architectural Fragmentation and Immune Reprogramming in Lung Adenocarcinoma Evolution

The progression of lung adenocarcinoma (LUAD) from precancerous lesions to invasive carcinoma entail...

Ensemble-DeepSets: an interpretable deep learning framework for single-cell resolution profiling of immunological aging

Immunological aging (immunosenescence) drives increased susceptibility to infections and reduced vac...

Successful Predictive Modeling of Pollen Fitness Phenotypes Is Enabled by Measures of Expression Specificity

The ability to predict phenotypes from genotypes in multicellular organisms remains limited despite ...

Assessing Inflammatory Protein Biomarkers in COPD Subjects with and without Alpha-1 Antitrypsin Deficiency

Individuals homozygous for the Alpha-1 Antitrypsin (AAT) Z allele (Pi*ZZ) exhibit heterogeneity in C...

MUTATE: A Human Genetic Atlas of Multi-organ AI Endophenotypes using GWAS Summary Statistics

Artificial intelligence (AI) has been increasingly integrated into imaging genetics to provide inter...

Machine learning models predict long COVID outcomes based on baseline clinical and immunologic factors

The post-acute sequelae of SARS-CoV-2 (PASC), also known as long COVID, remain a significant health ...

A Deep Learning–Based Automated Detection of Mucus Plugs in Chest CT

This study presents a novel two stage deep learning algorithm for automated detection of mucus plugs...

Automated Detection of Faciobrachial Dystonic Seizures Related Events in LGI1 Autoimmune Encephalitis Patients with Wearables

To evaluate the potential of wrist-worn wearable devices to detect and quantify Faciobrachial Dyston...

Expanding cholera serosurveillance to vaccinated populations

Mass oral cholera vaccination campaigns targeted at subnational areas with high incidence are centra...

Blood Immuno-metabolic Biomarker Signatures of Depression and Affective Symptoms in Young Adults

Depression is associated with alterations in immuno-metabolic biomarkers, but it remains unclear whe...

Revolutionizing COPD and Asthma Management with Artificial Intelligence

The integration of artificial intelligence (AI) into the management of chronic obstructive pulmonary...

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