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Alternative Medicine

Latest AI and machine learning research in alternative medicine for healthcare professionals.

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CIA-net: Cross-modality interaction and aggregation network for ovarian tumor segmentation from multi-modal MRI.

Magnetic resonance imaging (MRI) is an essential examination for ovarian cancer, in which ovarian tumor segmentation is crucial for personalized diagnosis and treatment planning. However, ovarian tumors often present with mixed cystic and solid regions in imaging, posing additional difficulties for automatic segmentation. In clinical practice, radiologists use T2-weighted imaging as the main modal...

Dec 11 2025 41406671

Lipidomics-driven insights into acupuncture mechanisms: From dynamic signaling networks to multi-dimensional regulations.

This review summarizes lipidomics as a key approach to dissect the multi-dimensional regulatory mechanisms of acupuncture, and reveals the role of lipid networks serve as critical 'molecular transducers' in the conversion of mechanical stimulation to biochemical signals. It systematically illustrates how lipid molecules mediate acupuncture's integrative regulation of the 'metabolic-immune-neurolog...

Dec 11 2025 41485437
Decoding plant physiology through systems biology: Integrative multi-omics and computational perspectives for next-generation crop design.

The convergence of high-resolution multi-omics technologies with computational systems biology is transforming plant physiology by enabling predictive...

Dec 10 2025 41376168
Major depressive disorder and Hashimoto's thyroiditis: Shared immunometabolic signatures revealed by integrative transcriptomics.

Major depressive disorder (MDD) and Hashimoto's thyroiditis (HT) frequently co-occur, yet their shared molecular underpinnings remain unclear. We perf...

Dec 7 2025 41365448
Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review).

Alternative splicing (AS) is one of the principal mechanisms of post‑transcriptional regulation that confers transcriptomic plasticity and proteomic d...

Dec 5 2025 41347834
Evaluating the Role of Artificial Intelligence in Fetal Medicine: Opportunities, Evidence, and Challenges, A Narrative Review.

Artificial intelligence has emerged as a promising tool in fetal medicine, with applications in prenatal imaging, anomaly detection, and biometric ana...

Dec 4 2025 41576327
Integrated m6A reader network in acute myeloid leukemia: prognostic modeling, immune modulation, and functional validation of YTHDF3.

Emerging evidence highlights RNA N6-methyladenosine (m6A) modifications as pivotal regulators of tumorigenesis, yet the synergistic roles of m6A reade...

Dec 4 2025 41349468
Multi-omic biomarker detection in ovarian cancer.

Ovarian cancer remains one of the most lethal gynecologic malignancies, largely because of late-stage diagnosis and the absence of reliable biomarkers...

Dec 3 2025 41349936
Digital Dentistry in Clinical Practice: A Scoping Review of Current Capabilities and Future Directions.

Digital technologies are transforming oral healthcare by enhancing prevention, diagnostics, treatment, and maintenance procedures. However, few compre...

Nov 29 2025 41319579
A comprehensive image dataset of jute diseases.

This Data Descriptor presents the Jute Diseases Image Dataset; a curated collection of 1390 high-resolution images aimed at supporting the development...

Nov 28 2025 41438649
Reveal a risk and potential mechanism for keratoconus progression with isotretinoin: Toxicogenomic, transcriptomics and real-world evidence insights.

PURPOSE: Limited clinical data and unstable animal models hinder understanding isotretinoin-induced keratoconus. We addressed this by integrating phar...

Nov 22 2025 41285218
Explainable machine learning algorithm for classifying resting-state functional MRI in amyotrophic lateral sclerosis.

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects multiple brain systems. Altered brain function can b...

Nov 21 2025 41308261
Bridging tradition and innovation: Acupuncture for depression through clinical efficacy and neurobiological insights.

BACKGROUND: To elucidate the research progress on acupuncture therapy as a complementary and alternative medicine treatment for depression by reviewin...

Nov 19 2025 41265714
Digital Eye: Deep Learning for Detecting Physeal Fractures of the Pediatric Distal Radius.

BACKGROUND: Distal radial fractures (DRFs) are some of the most common pediatric injuries, often involving the physis. Diagnostic accuracy can be chal...

Nov 8 2025 41488804
Genomics of drug target prioritization for complex diseases.

Drug development faces persistent challenges, with high attrition rates and unexpected adverse effects contributing to clinical trial failures. The re...

Nov 6 2025 41198831
Few-shot learning and explainable AI for colon cancer histopathology: A prototypical network with multi-technique interpretability.

BACKGROUND: Colon cancer diagnosis from histopathology is challenging due to limited annotated data and the lack of interpretability in deep models. O...

Nov 3 2025 41232395
Precision medicine in orthopaedics: A review of current technologies and future directions.

PURPOSE: To synthesise the paradigm shift towards precision medicine in orthopaedics, where individual anatomical, biomechanical, molecular and kinema...

Nov 1 2025 41174934
Artificial intelligence, machine learning and omic data integration in osteoarthritis.

OBJECTIVE: Artificial intelligence (AI), particularly its subfield of machine learning (ML), offer promising tools for integrating and interpreting hi...

Oct 28 2025 41167326
Multimodal deep learning for acute myocardial infarction detection from 12-lead electrocardiogram: a multi-centre study with cross-hospital validation.

AIMS: Acute myocardial infarction (AMI) remains a leading global cause of mortality, where timely diagnosis is critical to enable early intervention. ...

Oct 27 2025 41624556
Multi-modal deep-learning troponin prediction from electrocardiograms and demographic data.

AIMS: Electrocardiograms (ECGs) and troponin (Tn) testing are essential tools for the diagnosis and management of cardiac conditions. Prompt diagnosis...

Oct 27 2025 41624563
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