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Alternative Medicine

Latest AI and machine learning research in alternative medicine for healthcare professionals.

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What's the Meta Now? More Updates on the Problems with Systematic Reviews.

BACKGROUND: Systematic reviews are intended to provide trustworthy evidence synthesis, yet previous iterations of this living review have identified numerous recurring problems in their conduct and reporting. This article presents the third version and second update of the living systematic review examining issues raised across the academic literature. METHODS: Using consistent eligibility criteri...

Jun 27 2026 42364666

Integrative machine learning and experimental validation reveal the molecular mechanisms of 2-bromo-4,6-dinitroaniline nephrotoxicity: CD45 and cyclophilin C as early response biomarkers of renal tubular injury.

2-Bromo-4,6-dinitroaniline (BDNA), a synthetic intermediate of brominated azo dyes, poses potential nephrotoxicity risks; however, its early molecular injury mechanisms remain elusive. This study integrated network toxicology prediction, machine learning algorithms (least absolute shrinkage and selection operator [LASSO], support vector machine recursive feature elimination [SVM-RFE], and random f...

Jun 27 2026 42364781
State-of-the-art technologies for the digital transformation of healthcare services - a systematic scoping review.

BACKGROUND: The implementation of digital technologies within health services promises increased performance, quality, and efficiency. However, eviden...

Jun 27 2026 42365262
A fully optimized deep learning framework for explainable and efficient kidney stone detection in computed tomography imaging.

PURPOSE: To develop and rigorously evaluate a hyperparameter-optimized custom convolutional neural network for kidney stone detection on axial compute...

Jun 27 2026 42362935
Machine learning-enhanced nano-QSAR and multiscale modeling for predictive nanomedicine: applications in herbal therapeutics and neglected tropical diseases.

Nanomedicine has transformed targeted drug delivery, yet the complexity of nano-bio interactions continues to hinder rational nanoparticle design. Pre...

Jun 26 2026 42360577
Clinical applications of digital twin technology in In Vitro Fertilisation.

BACKGROUND: Digital twin technology, originating from aerospace and manufacturing industries, has emerged as a transformative tool in healthcare. In v...

Jun 26 2026 42361654
The complementary roles of oversight, education, and collaboration in the responsible integration of artificial intelligence in radiation medicine: White paper of (CADRA).

Artificial intelligence (AI) is poised to fundamentally transform radiation medicine, with growing influence across clinical decision-making, workflow...

Jun 25 2026 42349037
Integrative multi-omics and single-cell analysis identifies EGFR pathway activation and metabolic reprogramming as potential synthetic lethal vulnerabilities in resistance to the FGFR inhibitor AZD4547.

BACKGROUND: Although fibroblast growth factor receptor (FGFR) inhibitors (FGFRi) have demonstrated clinical promise, the inevitable emergence of acqui...

Jun 25 2026 42351126
Annexin A2 as a Therapeutic Target of Artemisiae Scopariae Herba-derived Quercetin in Preventing Malignant Progression from Primary Sclerosing Cholangitis to Cholangiocarcinoma: An Integrative Study.

ETHNOPHARMACOLOGICAL RELEVANCE: Artemisiae Scopariae Herba (ASH) is traditionally used to treat cholestatic liver diseases and exhibits anti-tumour po...

Jun 24 2026 42341858
Automation in the IVF laboratory in 2026: four technology domains, an asymmetric evidence base, and the case for parallel development with clinician-side automation.

BACKGROUND: Operator-dependent laboratory tasks-embryo selection, vitrification and warming, and intracytoplasmic sperm injection (ICSI)-have been the...

Jun 24 2026 42337202
Drug repositioning as an antivirulence strategy: Ketoprofen targets quorum sensing and biofilm in Serratia sp.

Serratia sp. are opportunistic Gram-negative bacteria capable of forming robust biofilms and expressing a wide range of quorum sensing (QS)-regulated ...

Jun 23 2026 42334552
Large reasoning models as thinking machines for medicine.

Conventional artificial intelligence has achieved remarkable feats in identifying associations and predictive patterns, yet its limitations in causal ...

Jun 23 2026 42337060
Human Resource Management, Complementarity and Hospital Performance: Evidence From the English NHS.

This study investigates the role of complementary clusters of human resource management (HRM) practices in explaining the persistent productivity vari...

Jun 22 2026 42330310
Childhood exposure to traffic-related air pollution and lung function at age 10 years: evidence of nutritional modification in a birth cohort.

BACKGROUND: Exposure to traffic-related air pollution has been associated with impaired lung function in children, yet heterogeneity in susceptibility...

Jun 22 2026 42330695
Interpersonal neural synchrony in joint music-making and conversation: toward an integrative Marr-level account.

Joint music-making and conversation are two fundamental forms of human interaction. A growing number of hyperscanning studies have examined interperso...

Jun 22 2026 42331124
Emerging robotic platforms in urologic surgery: a bibliometric and visualization analysis of global trends and research hotspots.

Robot-assisted surgery has become an important component of modern urologic practice, and the emergence of alternative robotic platforms has accelerat...

Jun 22 2026 42324375
MTA-Swin: A Multi-Token Attention Swin Transformer for Brain Tumor Classification with Leakage-Free MRI Benchmarking.

Brain tumors represent a major global health challenge, and accurate classification of brain tumors is essential for effective diagnosis and treatment...

Jun 22 2026 42324433
Beyond surgical risk: Multidimensional predictors of postoperative arm morbidity after breast cancer treatment.

BACKGROUND: Postoperative upper-limb morbidity following breast cancer treatment is common and clinically significant, encompassing pain, functional i...

Jun 20 2026 42330687
Molecular mechanism by which perfluorooctane sulfonate regulates the initiation and progression of prostate cancer via the ENTPD5-adenine axis.

Perfluorooctane sulfonate (PFOS), a persistent member of the per- and polyfluoroalkyl substances family, has been increasingly associated with adverse...

Jun 19 2026 42319417
An Attention-Enhanced ViT-HLNN Hybrid Ensemble Framework for Multi-Class Gastrointestinal Disease Classification.

Gastrointestinal (GI) diseases such as polyps, esophagitis, and ulcerative colitis pose significant diagnostic challenges due to subtle visual pattern...

Jun 19 2026 42321239
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