Geriatrics

Alzheimer's Disease

Latest AI and machine learning research in alzheimer's disease for healthcare professionals.

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Geriatrics Subcategories: Alzheimer's Disease Medicare
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Multimodal Ordinal Modeling of Alzheimer's Disease Severity Using Structural MRI and Clinical Data

Neurodegenerative diseases such as Alzheimer's disease (AD) require accurate and scalable tools for ...

Candidate Molecular Subtypes of Cognitive Resilience in Alzheimers Disease: A Multi-Cohort Machine Learning and Neuroimaging Study

Background: Cognitive resilience (CR) in Alzheimers disease (AD) refers to preserved cognitive funct...

Sleep EEG Signal Criticality as a Non-Invasive Predictor of Cognitive Decline in Dementia

Early detection of neurodegeneration remains a critical clinical challenge. This study investigates ...

Transition-Based Digital Twin Modelling for Alzheimer's Disease under Sparse Longitudinal Data

Alzheimer's disease (AD) progression is highly heterogeneous and is typically observed through spars...

Immediate to longer-term neurophysiological impact of acute neural network disruption

Despite substantial interest in how neural systems recover over time after acute neurological events...

Multilingual Detection of Alzheimer's Disease from Speech: A Cross-Linguistic Transfer Learning Approach

The development of multilingual Alzheimer's Disease Dementia (AD) detection models presents signific...

Cross-scale spatially-aware generative modeling of transcriptomic programs underlying neurodegenerative brain organization

Neurodegenerative disorders such as Alzheimer's disease exhibit highly organized patterns of regiona...

Predicting the timing of first sustained cognitive worsening in Alzheimer's disease using real-world clinical data and machine learning

Background: Cognitive assessments are sparsely documented in electronic health records (EHRs), limit...

Multiplex Proteomics of Lewy Body Dementia Reveals Cerebrospinal Fluid Biomarkers of Clinical and Neuropathological Heterogeneity

Lewy body dementia (LBD), which encompasses Parkinson's disease dementia (PDD) and Dementia with Lew...

Towards A Foundation Model for Clinical Voice Biomarkers

Vocal biomarkers, encompassing voice and speech, have largely been developed for individual conditio...

A Multi-Agent RAG Framework for Biomedical Literature Analysis

Background: The biomedical literature is expanding at an unprecedented rate, with over 4,000 new art...

Comparing Pathway-Informed Polygenic Risk Score Strategies: A multi-cohort evaluation of Amyloid-β

Objective: To systematically evaluate pathway-informed polygenic risk score (PRS) strategies and det...

Wearable and Interview-based Assessment of Psychological Risk in Alzheimers Caregivers: Machine Learning vs. Large Language Models

Spousal caregivers of individuals with Alzheimers disease and related dementias frequently experienc...

CSV-ViT: A Vision Transformer with the Variable-sized Cortical Supervertices for Detection of Alzheimer's Disease Pathologies

Confirming Alzheimer's disease (AD) typically relies on positron emission tomography (PET), which re...

A Multimodal Framework for Dementia Detection via Linguistic and Acoustic Representation Learning

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dement...

ARMA-C3: A Contrastive ARMA Convolutional Framework for Unsupervised and Semi-supervised Classification

In biomedical and neurodegenerative disorders, accurate and early disease identification remains cha...

Does the sequence of a disordered protein encode small molecule binding paths?

Ligand binding to intrinsically disordered proteins resists description in terms of conventional bin...

Predicting Autopsy-Confirmed Neuropathology across Clinical, Neuroimaging, and CSF Biomarkers using Machine Learning

Accurate in vivo prediction of neuropathology is critical for advancing diagnosis and treatment of A...

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