Latest AI and machine learning research in alzheimer's disease for healthcare professionals.
Metabolic dysfunction-associated steatohepatitis (MASH) is a complex liver disease whose pathogenesis involving endoplasmic reticulum (ER) stress and ferroptosis. However, key regulatory genes remain poorly understood, hindering the development of effective therapeutic targets. This study aims to identify genes linked to ER stress and ferroptosis through bioinformatics and experimental validation,...
Alzheimer's disease (AD) is a neurodegenerative disorder that severely impairs cognitive function across various age groups, ranging from early to late sixties. It progresses from mild to severe stages, so an accurate diagnostic tool is necessary for effective intervention and treatment planning. This work proposes a novel AD classification architecture that integrates depthwise separable convol...
PURPOSE OF REVIEW: This review explores the use of brain age estimation from MRI scans as a biomarker of brain health. With disorders like Alzheimer's...
PURPOSE OF REVIEW: Cardiac amyloidosis is characterized by systolic and diastolic abnormalities due to deposition of amyloid fibril within the myocard...
Heterogeneity is a fundamental characteristic of brain diseases, distinguished by variability not only in brain atrophy but also in the complexity of ...
Alzheimer's disease (AD) and atherosclerosis (AS) are two interacting diseases mostly affecting aged adults. AD is characterized by the deposition of ...
MRI brain scans alone are not a definitive measure of dementia. Deep-learning algorithms (DLA) and professional human opinion are necessary for diagno...
The objective of this study was to compare twenty-six polysomnography (PSG) parameters between the groups utilizing automatic scoring (AS) software an...
Stochastic gradient descent (SGD) performed in an asynchronous manner plays a crucial role in training large-scale machine learning models. However, t...
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Recent studies have identified intercellular networks for material exchange by bridge-like nanotubular structures, yet their existence in neurons rema...
BACKGROUND: Alzheimer's disease (AD) is a severe neurodegenerative disorder, yet its molecular mechanisms remain incompletely understood. It is known ...
BACKGROUND: At present, the world is in the background of severe aging population challenges. Mild cognitive impairment (MCI), an intermediate state b...
Age-related macular degeneration (AMD) is a multifactorial retinal disease influenced by complex molecular mechanisms, including genetic susceptibilit...
OBJECTIVE: Cortical regions such as parietal area H (PH) and the fundus of the superior temporal sulcus (FST) are involved in higher visual function a...
Alzheimer's disease (AD), the most common form of dementia, is marked by cognitive decline and amyloid-beta (Aβ) plaque deposition in the brain. Micro...
INTRODUCTION: In 2024, 11 European scientific societies/organizations and one patient advocacy association have defined a patient-centered biomarker-b...
Diagnosing Alzheimer's disease based on gene expression data extracted from microarrays is still an open field of research. Due to the availability of...
The recent approval of anti-amyloid pharmaceuticals for the treatment of Alzheimer's disease (AD) has created a pressing need for the ability to accur...
Single-cell RNA sequencing has demonstrated that the presence of parenchymal amyloid plaques and intracellular hyperphosphorylated tau pathology is as...