Geriatrics

Alzheimer's Disease

Latest AI and machine learning research in alzheimer's disease for healthcare professionals.

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Geriatrics Subcategories: Alzheimer's Disease Medicare
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Random field image representations speed up binary discrimination of brain scans and estimate a phenotype glioblastoma cancer cell model.

MRI brain scans alone are not a definitive measure of dementia. Deep-learning algorithms (DLA) and professional human opinion are necessary for diagnosis. Yet, sample sizes are prohibitively large to train a typical DLA, which itself takes considerable computation time to produce diagnostically useful information from contrasting image features. We introduce analytic simplifications to this proces...

May 22 2025 40470222

A Comparative Analysis Of Automatic And Manual Scoring Methods In Polysomnography.

The objective of this study was to compare twenty-six polysomnography (PSG) parameters between the groups utilizing automatic scoring (AS) software and manual scoring (MS) technique. Two MS groups, each comprising technicians with sleep scoring experience ranging from 5 to 8 years, were established. One group consisted of three technicians while the other included four technicians. PSG record of t...

May 21 2025 40396963
Towards Understanding the Generalizability of Delayed Stochastic Gradient Descent.

Stochastic gradient descent (SGD) performed in an asynchronous manner plays a crucial role in training large-scale machine learning models. However, t...

May 21 2025 40397624
Intercellular communication in the brain via dendritic nanotubular network.

Recent studies have identified intercellular networks for material exchange by bridge-like nanotubular structures, yet their existence in neurons rema...

May 21 2025 40475405
A pathway-informed disease-related gene identification approach and its application to screen novel risk genes for Alzheimer's disease.

BACKGROUND: Alzheimer's disease (AD) is a severe neurodegenerative disorder, yet its molecular mechanisms remain incompletely understood. It is known ...

May 21 2025 40406678
Machine learning applied to mild cognitive impairment: bibliometric and visual analysis from 2015 to 2024.

BACKGROUND: At present, the world is in the background of severe aging population challenges. Mild cognitive impairment (MCI), an intermediate state b...

May 21 2025 40470497
Integrating Artificial Intelligence and Precision Therapeutics for Advancing the Diagnosis and Treatment of Age-Related Macular Degeneration.

Age-related macular degeneration (AMD) is a multifactorial retinal disease influenced by complex molecular mechanisms, including genetic susceptibilit...

May 20 2025 40428167
Functional MRI Analysis of Cortical Regions to Distinguish Lewy Body Dementia From Alzheimer's Disease.

OBJECTIVE: Cortical regions such as parietal area H (PH) and the fundus of the superior temporal sulcus (FST) are involved in higher visual function a...

May 19 2025 40384035
Layer-Specific Colocalization of Microglia with Amyloid Plaques in the Middle Temporal Gyrus Predicts Cognitive Decline in Alzheimer's Disease.

Alzheimer's disease (AD), the most common form of dementia, is marked by cognitive decline and amyloid-beta (Aβ) plaque deposition in the brain. Micro...

May 19 2025 40423635
AI-based staging, causal hypothesis and progression of subjects at risk of Alzheimer's disease: a multicenter study.

INTRODUCTION: In 2024, 11 European scientific societies/organizations and one patient advocacy association have defined a patient-centered biomarker-b...

May 19 2025 40458467
Alzheimer's diagnosis by an efficient pipelined gene selection model based on statistical and biological data analysis.

Diagnosing Alzheimer's disease based on gene expression data extracted from microarrays is still an open field of research. Due to the availability of...

May 18 2025 40403352
Brain metabolic imaging-based model identifies cognitive stability in prodromal Alzheimer's disease.

The recent approval of anti-amyloid pharmaceuticals for the treatment of Alzheimer's disease (AD) has created a pressing need for the ability to accur...

May 17 2025 40382421
High-Resolution Spatial Profiling of Microglia Reveals Proximity Associated Immunometabolic Reprogramming in Alzheimer's Disease.

Single-cell RNA sequencing has demonstrated that the presence of parenchymal amyloid plaques and intracellular hyperphosphorylated tau pathology is as...

May 16 2025 40462993
Early detection of Alzheimer's disease progression stages using hybrid of CNN and transformer encoder models.

Alzheimer's disease (AD) is a neurodegenerative disorder that affects memory and cognitive functions. Manual diagnosis is prone to human error, often ...

May 14 2025 40368958
The two cut-offs approach for plasma p-tau217 in detecting Alzheimer's disease in subjective cognitive decline and mild cognitive impairment.

BACKGROUND: The study aimed to explore the applicability of plasma phosphorylated tau (p-tau)217 in identifying patients with subjective cognitive dec...

May 11 2025 40357140
Integrating Fine-Tuned LLM with Acoustic Features for Enhanced Detection of Alzheimer's Disease.

Dementia represents a global public health concern, with the early detection of Alzheimer's disease, the most prevalent form of dementia, being of par...

May 9 2025 40343819
Study on the effect and mechanism of PM on the expression of alzheimer's-like lesions related proteins in SH-SY5Y cells.

Fine particulate matter (PM) is recognized as one of the most harmful environmental pollutants to human health. Current research indicates that PM exh...

May 9 2025 40348349
Neuroprotective Effects of Shrimp Oil Against Oxidative Stress in Chronic Cerebral Hypoperfusion Rats.

Shrimp oil is rich in polyunsaturated fatty acids and astaxanthin, which possesses high antioxidant activity. This study aimed to investigate the impa...

May 8 2025 40341803
Interpretable MRI-Based Deep Learning for Alzheimer's Risk and Progression.

Timely intervention for Alzheimer's disease (AD) requires early detection. The development of immunotherapies targeting amyloid-beta and tau underscor...

May 7 2025 40385384
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