Alzheimer's Disease

Deep convolutional neural network-based identification and biological evaluation of MAO-B inhibitors.

Parkinson's disease (PD) is one of the most prominent motor disorder of adult-onset dementia connected to memory and other cognitive abilities. Individuals with this vicious neurodegenerative condition tend to have an elevated expression of Monoamine Oxidase-B (MAO-B) that catalyzes the oxidative deamination of aryalkylamines neurotransmitters with concomitant reduction of oxygen to hydrogen perox...

A deep learning approach for non-invasive Alzheimer's monitoring using microwave radar data.

Over 50 million people globally suffer from Alzheimer's disease (AD), emphasizing the need for efficient, early diagnostic tools. Traditional methods like Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) scans are expensive, bulky, and slow. Microwave-based techniques offer a cost-effective, non-invasive, and portable solution, diverging from conventional neuroimaging practices. This ...

Automated Neural Architecture Search for Cardiac Amyloidosis Classification from [18F]-Florbetaben PET Images.

Medical image classification using convolutional neural networks (CNNs) is promising but often requires extensive manual tuning for optimal model defi...

Pain Assessment for Patients with Dementia and Communication Impairment: Feasibility Study of the Usage of Artificial Intelligence-Enabled Wearables.

BACKGROUND: Recent studies on machine learning have shown the potential to provide new methods with which to assess pain through the measurement of si...

Deep learning-based binary classification of beta-amyloid plaques using 18 F florapronol PET.

PURPOSE: This study aimed to investigate a deep learning model to classify amyloid plaque deposition in the brain PET images of patients suspected of ...

Explainability of CNN-based Alzheimer's disease detection from online handwriting.

With over 55 million people globally affected by dementia and nearly 10 million new cases reported annually, Alzheimer's disease is a prevalent and ch...

Can robots lie? A posthumanist approach to robotic animals and deceptive practices in dementia care.

Robotic animals are designed to resemble real, living animals, but at the same time, dementia care guidelines and policies often emphasize the value o...

3-1-3 Weight averaging technique-based performance evaluation of deep neural networks for Alzheimer's disease detection using structural MRI.

Alzheimer's disease (AD) is a progressive neurological disorder. It is identified by the gradual shrinkage of the brain and the loss of brain cells. T...

Early diagnosis of Alzheimer's Disease based on multi-attention mechanism.

Alzheimer's Disease is a neurodegenerative disorder, and one of its common and prominent early symptoms is language impairment. Therefore, early diagn...

Multi-modality artificial intelligence-based transthyretin amyloid cardiomyopathy detection in patients with severe aortic stenosis.

PURPOSE: Transthyretin amyloid cardiomyopathy (ATTR-CM) is a frequent concomitant condition in patients with severe aortic stenosis (AS), yet it often...

Integrated Ultrasound-Enrichment and Machine Learning in Colorimetric Lateral Flow Assay for Accurate and Sensitive Clinical Alzheimer's Biomarker Diagnosis.

The colloidal gold nanoparticle (AuNP)-based colorimetric lateral flow assay (LFA) is one of the most promising analytical tools for point-of-care dis...

Criticality of Nursing Care for Patients With Alzheimer's Disease in the ICU: Insights From MIMIC III Dataset.

Alzheimer's disease (AD) patients admitted to intensive care units (ICUs) exhibit varying survival outcomes due to the unique challenges in managing A...

AI-driven innovations in Alzheimer's disease: Integrating early diagnosis, personalized treatment, and prognostic modelling.

Alzheimer's disease (AD) presents a significant challenge in neurodegenerative research and clinical practice due to its complex etiology and progress...

Automated classification of Alzheimer's disease, mild cognitive impairment, and cognitively normal patients using 3D convolutional neural network and radiomic features from T1-weighted brain MRI: A comparative study on detection accuracy.

OBJECTIVES: Alzheimer's disease (AD) is a common neurodegenerative disorder that primarily affects older individuals. Due to its high incidence, an ac...

Predicting Adherence to Computer-Based Cognitive Training Programs Among Older Adults: Study of Domain Adaptation and Deep Learning.

BACKGROUND: Cognitive impairment and dementia pose a significant challenge to the aging population, impacting the well-being, quality of life, and aut...

A Novel Method to Identify Mild Cognitive Impairment Using Dynamic Spatio-Temporal Graph Neural Network.

Resting-state functional magnetic resonance imaging (rs-fMRI) has been widely used in the identification of mild cognitive impairment (MCI) research, ...

Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning.

Systemic amyloidosis involves the deposition of misfolded proteins in organs/tissues, leading to progressive organ dysfunction and failure. Congo red ...

Mild cognitive impairment prediction based on multi-stream convolutional neural networks.

BACKGROUND: Mild cognitive impairment (MCI) is the transition stage between the cognitive decline expected in normal aging and more severe cognitive d...

Comorbidity-based framework for Alzheimer's disease classification using graph neural networks.

Alzheimer's disease (AD), the most prevalent form of dementia, requires early prediction for timely intervention. Current deep learning approaches, pa...

A Pre-Voiding Alarm System Using Wearable Ultrasound and Machine Learning Algorithms for Children With Nocturnal Enuresis.

Nocturnal enuresis is a bothersome condition that affects many children and their caregivers. Post-voiding systems is of little value in training a ch...