Anesthesiology

[Reflections on surgical management strategies for locally advanced gastric cancer after neoadjuvant immunotherapy].

Neoadjuvant immunotherapy is reshaping the treatment landscape of locally advanced gastric cancer (GC). The central clinical challenge has expanded from whether immunotherapy can enhance treatment efficacy to accurate identification of patients who are most likely to benefit and optimization of the subsequent surgical intervention. Accumulating evidence indicates that perioperative immunotherapy-b...

Skin-to-skin contact improves sleep stability in preterm infants.

BACKGROUND: Sleep supports neurophysiological maturation in preterm infants, yet the impact of developmental care interventions on sleep remains poorly quantified. Skin-to-skin contact (SSC) improves physiological stability, but its effects on sleep structure measured with automated methods are unclear. We hypothesized that SSC increases sleep duration and reduces sleep fragmentation. METHODS: In ...

Real-Time AI Voice Translation for International Medical Conferences and Beyond: Enabling Multilingual Scientific Exchange.

BACKGROUND: Language barriers continue to limit participation in international medical communication, and recent advances in artificial intelligence n...

Machine learning combined with fMRI identifies dynamic brain network alterations in post-stroke depression: A dual-center cross-sectional study.

OBJECTIVE: Post-stroke depression (PSD) is under-recognized and associated with poorer rehabilitation outcomes and quality of life. We characterized P...

Defining 'psychedelic'.

Humphry Osmond coined the term 'psychedelic' in 1956, conjoining 'psyche' for 'soul' and 'delic' for 'to manifest' or 'illuminate'. Soul-illumination ...

Knowledge and perception of artificial intelligence among operating room staff in educational hospitals: a cross-sectional survey.

BACKGROUND: Successful implementation of artificial intelligence (AI) in healthcare depends not only on technological performance but also on the read...

What predicts prolonged length of stay after surgery for cervical spondylotic myelopathy? A QOD CSM study.

OBJECTIVE: Cervical spondylotic myelopathy (CSM) is a leading cause of spinal cord dysfunction requiring surgical intervention. Prolonged length of st...

Global research trends in perioperative pressure injury prevention: A bibliometric analysis from repositioning to technology-assisted strategies.

BACKGROUND: Perioperative pressure injuries remain a major patient safety challenge, particularly among critically ill and immobilised patients. Altho...

Postoperative Nocardia cyriacigeorgica infection after glioblastoma resection: correlating metagenomic next-generation sequencing with conventional microbiology.

Postoperative nocardial infection after cranial surgery is rare and difficult to diagnose because Nocardia spp. grow slowly in conventional culture. M...

Rapid Resolution of Hypoxemia is Common and Associated with Lower Mortality Among Intubated Patients with Acute Hypoxemic Respiratory Failure.

ObjectiveTo evaluate the prevalence, clinical trajectory, and biologic phenotype of patients with rapidly improving acute hypoxemic respiratory failur...

Pharmacological evidence for propagation dynamics of TMS-evoked potentials in the human brain.

BACKGROUND: Transcranial magnetic stimulation-evoked potentials (TEPs) propagate from the stimulation site to distributed brain networks, with early p...

Biomarkers of nivolumab benefit in resectable non-small cell lung cancer.

Perioperative nivolumab significantly improved event-free survival (EFS) compared with placebo in patients with resectable non-small cell lung cancer ...

Diagnostic decision-making, vertebral augmentation, and osteoporosis therapy in vertebral compression fractures: a narrative review.

Vertebral compression fractures (VCFs) represent the most prevalent osteoporotic fracture and constitute a growing cause of morbidity, mortality, and ...

Manual and automated capture of analgesic-responsive facial pain behaviors of unrestrained mice in a trigeminal neuralgia model.

Trigeminal neuralgia (TN), a devastating neuropathic pain condition, profoundly affects human well-being. Despite an initial response to carbamazepine...

Evaluating Retrieval-Augmented Large Language Models on Anesthesiology Board-Style Questions: Benchmark Study.

BACKGROUND: Open-source, mid-scale large language models (LLMs) have emerged as scalable, privacy-preserving alternatives to ultra-large foundation mo...

Correction: Hypoxemia prediction in pediatric patients under general anesthesia using machine learning: A retrospective observational study and external validation.

[This corrects the article DOI: 10.1371/journal.pone.0339276.].

Machine learning-based prediction of intraoperative blood transfusion in major surgery: exploiting clinical variables and systemic inflammatory indices.

BACKGROUND: Intraoperative blood transfusion is common in major surgery. Predicting transfusion risk may improve perioperative management, optimize bl...

Artificial Intelligence in Anesthesiology: Do Not Throw Caution to the Wind.

An interpretable multimodal biomechanical-radiological model for predicting fixation failure in osteoporotic hip fractures: A retrospective cohort study.

This study aimed to develop and validate a multimodal prediction model integrating biomechanical and radiological variables to predict internal fixati...

AI-Based Spatiotemporal Analysis Reveals Distinct Neuronal Markers of Morphine Response during Chronic Pain in Mice.

Treatment of chronic pain often relies on long term use of analgesics, such as opioids like morphine. However, the habit-forming natures of such subst...