Anxiety & Stress

Advances in root phenotyping: high-throughput imaging, computational tools and integrative approaches for crop improvement.

Climate change increasingly threatens global agriculture by intensifying abiotic stresses and destabilizing crop productivity, necessitating a deeper understanding of root-mediated traits governing resource acquisition and stress resilience. Here, we synthesize recent advances in root-centered plant phenomics, emphasizing how high-throughput phenotyping (HTP) enables high-resolution, scalable char...

Diagnostic value of machine-learning using conventional magnetic resonance imaging markers for pediatric idiopathic intracranial hypertension: a retrospective study.

BACKGROUND: Pediatric idiopathic intracranial hypertension can be challenging to diagnose; magnetic resonance imaging (MRI) signs are considered supportive, while lumbar puncture remains the diagnostic reference. OBJECTIVE: We evaluated whether a compact set of conventional magnetic resonance imaging markers, analyzed with supervised machine-learning, can assist in the diagnosis of idiopathic intr...

Application and effectiveness of artificial intelligence in adolescent mental health support and therapy: a scoping review.

BACKGROUND: Adolescents are highly vulnerable to mental health conditions, yet traditional counseling models may not fully address their evolving need...

Unraveling the molecular landscape of chronic radiation injury: From oxidative stress signaling to translational modeling (Review).

The expanding footprint of human radiation exposure, driven by advances in interventional diagnostics, the resurgence of the nuclear industry and the ...

Development of an interpretable machine learning model for predicting stress urinary incontinence following the delivery of a first child.

INTRODUCTION: The goal of this research is to use machine learning (ML) techniques to create a risk prediction model for postpartum stress urinary inc...

The role of nitrogen dioxide in the prevalence of adverse cardiovascular and cerebrovascular diseases in China: a national multi-pollutant geospatial analysis.

INTRODUCTION: Cardiovascular and cerebrovascular diseases (CCVDs) pose a severe global health threat, particularly among middle-aged and elderly popul...

Real‑World Clinical Characterization of Major Depressive Disorder and Treatment‑Resistant Depression Supported by Natural Language Processing: Multicenter Observational Study From the MOOD Project.

BACKGROUND: Major depressive disorder (MDD) and treatment-resistant depression (TRD) are heterogeneous conditions in which key clinical details are sp...

Understanding Blood-Injection-Injury Phobia: Do Not Miss the Point.

Needle and blood-injection-injury phobia is commonly encountered in the perioperative setting. It can significantly disrupt operating room throughput,...

Determinants of the Acceptance of Health-Related Use of Artificial Intelligence in the General Population: A Cross-Sectional Study.

The successful integration of artificial intelligence (AI) in healthcare hinges on user acceptance, which is influenced by cognitive, emotional, and c...

Targeting metabolic dysregulation in postmenopausal breast cancer: Synergistic effects of nutrition-based interventions and exercise on molecular and cellular pathways.

Postmenopausal females diagnosed with breast cancer who are undergoing aromatase inhibitor (AI) therapy often exhibit metabolic disturbances, which ma...

Risk prediction of depression- and anxiety-related psychological distress in a large multistage survey sample of Chinese adults: a multi-algorithm ensemble machine-learning model with SHAP.

OBJECTIVE: To develop an interpretable ensemble machine-learning model to support risk stratification of elevated depression- and anxiety-related psyc...

Integrating network pharmacology, molecular docking, machine learning, and experimental validation: puerarin improves sepsis-induced acute kidney injury via the Sirt1-Nrf2-HO-1 pathway.

Acute kidney injury (AKI) associated with sepsis has a high clinical mortality rate, and there is a lack of effective therapeutic targets; uncontrolle...

Decoding shared pathogenic networks of oxidative stress in neuropsychiatric disorders to prioritize multi-target therapeutics from natural products.

BACKGROUND: Neurodegenerative and psychiatric disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and ...

Beyond anxiety reduction: Psychological transformation and systemic contradictions in generative-AI-mediated language learning - A cultural-historical activity theory perspective.

This study explores the psychological transformation and contradictions arising from Generative AI (Gen-AI)-mediated language learning. Using Cultural...

An explainable machine learning framework for analyzing and predicting mental health problems among university students in Bangladesh.

Mental health problems (MHPs) among university students are an increasing public health concern globally, including in Bangladesh. While machine learn...

Differential cerebral white matter tract alterations in generalized anxiety disorder revealed by ultra-high-field 7 T diffusion-weighted imaging.

Generalized anxiety disorder (GAD) is characterized by chronic worry and emotional dysregulation, yet its underlying white matter (WM) microstructural...

Who Laughs, and Who Doesn't? Predicting Humor Skills From Personality, Social Anxiety, and Laughter Dispositions of Gelotophobia, Gelotophilia, and Katagelasticism.

Laughter-related dispositions, including gelotophobia (fear of being laughed at), gelotophilia (enjoyment of being laughed with), and katagelasticism ...

Reducing listening anxiety in blended learning: The role of AI-driven feedback and strategy in EFL education.

This mixed-methods study examined listening strategies, anxiety, and achievement among 436 vocational college EFL students in an AI-augmented blended ...

Polystyrene Microplastics Drive Chondrotoxicity in Osteoarthritis through Inducing ER Stress and Apoptosis via NFKB1 Activation.

Polystyrene microplastics (PS-MPs), recognized as widespread environmental contaminants, have been identified within human articular tissues. However,...

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation.

Antibiotic treatment failure, often driven by non-genetic mechanisms such as tolerance and persistence, remains a major global health challenge. β $\b...