Anxiety & Stress

Association of lipid profiles with suicide attempts in young adults with first-episode drug-naive major depressive disorder: a gender-specific analysis.

Major depressive disorder (MDD) is strongly associated with suicide risk. While lipid metabolism dysregulation is implicated in MDD pathophysiology, its specific relationship with suicide attempts (SA), particularly regarding sex-specific patterns, requires precise quantification. This study examined associations between lipid profiles and SA in young adults with first-episode, drug-naïve (FEDN) M...

Trajectory analysis of sleep disorders and anxiety-depression in female breast cancer patients undergoing chemotherapy: based on group-based Multi-Trajectory Model and machine learning.

BACKGROUND: Sleep disorders and anxiety-depression symptoms can significantly impair the quality of life and treatment adherence among breast cancer patients undergoing chemotherapy, while also increasing the risk of disease recurrence and mortality. Early identification of the progression trajectory and underlying causes of these symptoms is essential for providing personalized interventions for ...

Noninvasive and minimally invasive approaches for acute and chronic stress assessment in dairy cattle.

In modern dairy production, cattle are routinely exposed to a wide range of management-related, environmental, and biological stressors all of which c...

From molecular mechanisms to digital surveillance: the 2010-2025 evolution of benzodiazepine and Z-drug misuse research.

The misuse of benzodiazepines (BZDs) and Z-drugs poses significant global public health challenges. This study maps the scientific evolution and parad...

Integrative transcriptional regulatory networks governing cereal root responses to heavy metals and drought.

Cereal root systems perceive the onset of drought and heavy metal toxicity, which rapidly triggers signal transduction and extensive transcriptional r...

Scalable Left Ventricular ROI Annotation for Stress Perfusion Cardiac MRI using Deep Learning with Visual Refinement.

Accurate extraction of the left ventricular (LV)-centred region of interest (ROI) in stress perfusion cardiovascular magnetic resonance (CMR) remains ...

The readiness-anxiety paradox in artificial intelligence adoption among nursing students: a multidimensional regression analysis.

AIM: This study examined the relationship between medical artificial intelligence readiness and AI-related anxiety among nursing students following su...

Differential Effects of Prenatal Depression and Anxiety on Infant Sleep: Dual-Pathway Mechanisms Involving the HPA Axis and the Gut-Brain Axis.

STUDY OBJECTIVES: Prenatal psychological distress is associated with adverse offspring outcomes, including infant sleep disturbances and altered gut m...

Polystyrene nanoplastics trigger ferroptosis to aggravate ulcerative colitis: Integrated Multi-Database Bioinformatics, Machine Learning, and Experimental Validation.

BACKGROUND: Polystyrene is a common pollutant in microplastics, which can enter the human body in many ways. At the same time, the incidence of ulcera...

Reducing catastrophic forgetting in CNNs for plant stress classification using continual learning.

Plants face a range of biotic and abiotic stresses that reduce yield, and in agricultural countries like Bangladesh, manual detection of these stresse...

Ethical cognition, AI anxiety, and attitudes toward artificial intelligence: validation of the GAAIS, AT-EAI, and AIAS in an Albanian higher-education context.

BACKGROUND: Cross-cultural psychometric evidence on instruments measuring attitudes toward artificial intelligence (AI) remains scarce in transitional...

Integrative network toxicology and single-cell analysis implicates a potential TGFBR1-centered fibroblast remodeling axis in Benzo[a]pyrene-related atrial fibrillation.

BACKGROUND: Benzo[a]pyrene (BaP), an air pollution-related polycyclic aromatic hydrocarbon, may intersect with molecular pathways relevant to atrial f...

The Cancer Metallome Continuum: A Framework for Understanding Metal Dysregulation from Carcinogenesis to Therapeutic Resistance.

Metals and metalloids play essential roles in cancer biology, influencing redox balance, epigenetic regulation, immune responses, and cell death throu...

Systems-Level Developmental Reprogramming Under Waterlogging Stress in Cowpea Revealed by Integrated Phenotypic, Physiological, and Transcriptomic Analysis.

Cowpea (Vigna unguiculata (L.) Walp.) is a climate-resilient grain legume that contributes to nutritional and food safety in a variety of production r...

A predictive framework for assessing naproxen-mediated changes in Nitzschia dubia fucoxanthin levels via machine learning-driven dielectric sensing.

Naproxen (Nap), a widely used non-steroidal anti-inflammatory drug, can disturb algal physiology under sufficiently high exposure conditions. In this ...

Discrimination of generalized anxiety and major depressive disorders by machine learning of resting-state functional MRI.

OBJECTIVE: To address the clinical difficulty of differentiating Generalized Anxiety Disorder (GAD) from Major Depressive Disorder (MDD), this study a...

Dine in or take out dataset: user behavior in an interactive virtual reality café.

We present the Dine In or Take Out Dataset, a virtual reality dataset collected using a Meta Quest Pro, to understand how predominantly Gen Z individu...

A machine learning-based screening tool for classifying post-traumatic stress disorder in firefighters: Firefighter Latent Risk Evaluation (FLARE).

BACKGROUND: The prevalence of post-traumatic stress disorder (PTSD) among South Korean firefighters is likely to be under-reported because of stigma a...

The Emerging Roles of AI in Self-Directed Stress Management: Systematic Review.

BACKGROUND: Stress is widespread and carries substantial mental health, social, and economic burdens. Yet, access to clinician-led stress management r...

How mathematics anxiety relates to mathematical ability in AI agent-supported instruction: the moderating role of executive function.

Mathematical ability is widely recognized as a core indicator of students' cognitive development and academic achievement. However, in classroom envir...