Psychiatry

Anxiety & Stress

Latest AI and machine learning research in anxiety & stress for healthcare professionals.

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Integration of Transcriptomics With Interpretable Artificial Intelligence for Identifying Molecular Signatures of Physiological Stress in Sleep Deprivation.

Sleep deprivation induces systemic physiological stress accompanied by transcriptomic remodelling and immune dysregulation, yet objective molecular indicators for its assessment remain insufficient. This study integrated blood transcriptomic analysis with an interpretable machine learning framework to identify and validate candidate molecular signatures associated with sleep deprivation and their ...

Jun 1 2026 42216239

Screening and comprehensive analysis of endoplasmic reticulum stress-related biomarkers in atherosclerosis.

Atherosclerosis (AS) is a chronic inflammatory vascular disorder in which endoplasmic reticulum stress (ERS) plays a crucial regulatory role. However, the biological and translational relevance of ERS-related gene networks in AS remains largely unexplored. This study aimed to identify a robust ERS-related gene signature for AS. We integrated multiple GEO datasets and applied machine learning algor...

Jun 1 2026 42224166
Mechanistic Insights into PET-MPs-Aggravated Ischemic Stroke via Integrated Computational-Experimental Approaches.

Microplastics, especially the environmentally pervasive polyethylene terephthalate microplastics (PET-MPs), are important environmental pollutants, an...

May 31 2026 42219954
Predicting risk of mental health deterioration using multimodal data from the UK biobank.

INTRODUCTION: Prospective prediction of mental health risk is critical for early intervention to reduce the burden of depression, anxiety, and cogniti...

May 31 2026 42225233
Core body temperature is associated with visual representations of social group members.

Core body temperature (CBT) reflects a physiological state that may correspond with variation in social perception. In two exploratory studies, we exa...

May 31 2026 42218833
Effectiveness of AI and rule-based conversational agents for depression, anxiety and stress: A meta-analysis.

Depression, anxiety, and stress are significant global health burdens worsened by restricted access to care. Conversational agents (CAs), encompassing...

May 29 2026 42209800
Psychosocial Stress in the Chinese Community: Speech Analytics Through Linguistic and Acoustic Fusion Using Machine Learning.

BACKGROUND: Family caregivers experience significant stress due to intensive caregiving activities, making them highly susceptible to adverse psychoso...

May 29 2026 42214077
A recurrent interferon, stress, and survival axis identifies a rare malignant programme across glioblastoma single-cell, spatial, and longitudinal cohorts.

Glioblastoma exhibits profound intratumoral heterogeneity and rapid adaptation under stress, complicating durable therapeutic control. Here, a biologi...

May 29 2026 42214146
The impact of an artificial intelligence (AI)-assisted education program on mental health, social support and quality of life in older individuals with head and neck cancer: study protocol of a randomized controlled trial.

BACKGROUND: Head and neck cancer (HNC) is a common malignant tumor, and its treatment often leads to functional impairments in speech, swallowing, and...

May 29 2026 42215892
Multimodal phenotypic classification of generalized anxiety and panic using structural MRI data and psychosocial factors: machine learning results from the German National Cohort (NAKO) study.

Anxiety disorders are common and impairing mental health conditions. Using data from 26,378 adults in the German National Cohort Study (NAKO), we inve...

May 28 2026 42209472
Unraveling EFL students' technology self-efficacy, emotions and behavioral intentions in leveraging large language models: the serial mediation of perceptions and attitudes.

With the growing momentum to integrate artificial intelligence (AI) into education, large language models (LLMs) have shown great potential for Englis...

May 27 2026 42204630
Dynamic Mechanics and Longitudinal Changes in Temporomandibular Joint Structural Integrity.

BACKGROUND: Longitudinal changes in temporomandibular joint (TMJ) structures may reflect joint contact mechanics and jaw loading behaviours (Mechanobe...

May 27 2026 42200304
Machine learning-assisted meta-analysis reveals melatonin crosstalk regulating plant growth plasticity under heavy metal stress.

Heavy metal (HM) pollution is a traditional and ongoing global ecological issue that requires continuous attention. Although studies have focused on h...

May 27 2026 42203996
Deepfake perpetrator conversation for adults with sexual abuse-related posttraumatic stress disorder: intervention development and multiple baseline study protocol.

Background: A conversation between a victim and a perpetrator of sexual abuse has the potential to reduce posttraumatic stress disorder (PTSD) symptom...

May 26 2026 42189904
Predictive modeling and network analysis uncover novel regulators of multi-stress tolerance in Saccharomyces cerevisiae.

BACKGROUND: Understanding molecular responses to multi-stress conditions in Saccharomyces cerevisiae is crucial for optimizing industrial strains and ...

May 26 2026 42192287
Generative AI's Impact on the Mental Health of Medical Students: Scenario Analysis.

BACKGROUND: Generative artificial intelligence (AI) is quickly changing medical education, even as medical students still face high levels of stress, ...

May 26 2026 42190258
The association between generative artificial intelligence use and foreign language classroom anxiety.

This study examines the association between Generative Artificial Intelligence use and foreign language classroom anxiety (FLCA) among undergraduates ...

May 25 2026 42184800
Development and validation of the student readiness and anxiety scale for AI-assisted biology teaching (SRAS-AIBT).

As the use of artificial intelligence in education increases, determining student readiness and anxiety has become a necessity; however, the lack of a...

May 25 2026 42185485
Hallmarks of epithelial-mesenchymal plasticity in cancer.

Cancer stem cells (CSCs) drive tumour initiation, progression, metastasis, and therapy resistance through their remarkable plasticity, enabling dynami...

May 25 2026 42185888
Advances in root phenotyping: high-throughput imaging, computational tools and integrative approaches for crop improvement.

Climate change increasingly threatens global agriculture by intensifying abiotic stresses and destabilizing crop productivity, necessitating a deeper ...

May 24 2026 42178486
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