Anxiety & Stress

Integrative transcriptional regulatory networks governing cereal root responses to heavy metals and drought.

Cereal root systems perceive the onset of drought and heavy metal toxicity, which rapidly triggers signal transduction and extensive transcriptional reprogramming that underpins plant stress tolerance. This review discusses the transcriptional basis of root responses to abiotic stresses, emphasizing key regulatory genes and networks that orchestrate hormone signaling, redox dynamics, ion homeostas...

Scalable Left Ventricular ROI Annotation for Stress Perfusion Cardiac MRI using Deep Learning with Visual Refinement.

Accurate extraction of the left ventricular (LV)-centred region of interest (ROI) in stress perfusion cardiovascular magnetic resonance (CMR) remains challenging due to low signal-to-noise ratio (SNR), motion artefacts, high-dimensional image data, and limited annotated datasets. Efficient ROI localisation is an important preprocessing step for reducing irrelevant anatomical content and improving ...

The readiness-anxiety paradox in artificial intelligence adoption among nursing students: a multidimensional regression analysis.

AIM: This study examined the relationship between medical artificial intelligence readiness and AI-related anxiety among nursing students following su...

Differential Effects of Prenatal Depression and Anxiety on Infant Sleep: Dual-Pathway Mechanisms Involving the HPA Axis and the Gut-Brain Axis.

STUDY OBJECTIVES: Prenatal psychological distress is associated with adverse offspring outcomes, including infant sleep disturbances and altered gut m...

Polystyrene nanoplastics trigger ferroptosis to aggravate ulcerative colitis: Integrated Multi-Database Bioinformatics, Machine Learning, and Experimental Validation.

BACKGROUND: Polystyrene is a common pollutant in microplastics, which can enter the human body in many ways. At the same time, the incidence of ulcera...

Reducing catastrophic forgetting in CNNs for plant stress classification using continual learning.

Plants face a range of biotic and abiotic stresses that reduce yield, and in agricultural countries like Bangladesh, manual detection of these stresse...

Ethical cognition, AI anxiety, and attitudes toward artificial intelligence: validation of the GAAIS, AT-EAI, and AIAS in an Albanian higher-education context.

BACKGROUND: Cross-cultural psychometric evidence on instruments measuring attitudes toward artificial intelligence (AI) remains scarce in transitional...

Integrative network toxicology and single-cell analysis implicates a potential TGFBR1-centered fibroblast remodeling axis in Benzo[a]pyrene-related atrial fibrillation.

BACKGROUND: Benzo[a]pyrene (BaP), an air pollution-related polycyclic aromatic hydrocarbon, may intersect with molecular pathways relevant to atrial f...

The Cancer Metallome Continuum: A Framework for Understanding Metal Dysregulation from Carcinogenesis to Therapeutic Resistance.

Metals and metalloids play essential roles in cancer biology, influencing redox balance, epigenetic regulation, immune responses, and cell death throu...

Systems-Level Developmental Reprogramming Under Waterlogging Stress in Cowpea Revealed by Integrated Phenotypic, Physiological, and Transcriptomic Analysis.

Cowpea (Vigna unguiculata (L.) Walp.) is a climate-resilient grain legume that contributes to nutritional and food safety in a variety of production r...

A predictive framework for assessing naproxen-mediated changes in Nitzschia dubia fucoxanthin levels via machine learning-driven dielectric sensing.

Naproxen (Nap), a widely used non-steroidal anti-inflammatory drug, can disturb algal physiology under sufficiently high exposure conditions. In this ...

Discrimination of generalized anxiety and major depressive disorders by machine learning of resting-state functional MRI.

OBJECTIVE: To address the clinical difficulty of differentiating Generalized Anxiety Disorder (GAD) from Major Depressive Disorder (MDD), this study a...

A machine learning-based screening tool for classifying post-traumatic stress disorder in firefighters: Firefighter Latent Risk Evaluation (FLARE).

BACKGROUND: The prevalence of post-traumatic stress disorder (PTSD) among South Korean firefighters is likely to be under-reported because of stigma a...

The Emerging Roles of AI in Self-Directed Stress Management: Systematic Review.

BACKGROUND: Stress is widespread and carries substantial mental health, social, and economic burdens. Yet, access to clinician-led stress management r...

6PPD-quinone exposure and Alzheimer's disease: insights from integrative network pharmacology, transcriptomics, machine learning, and molecular docking.

OBJECTIVES: To systematically investigate the molecular associations between 6PPD-quinone (6PPD-Q), an environmental transformation product of the tir...

How mathematics anxiety relates to mathematical ability in AI agent-supported instruction: the moderating role of executive function.

Mathematical ability is widely recognized as a core indicator of students' cognitive development and academic achievement. However, in classroom envir...

Artificial intelligence and academic anxiety? a meta-analysis.

BACKGROUND: Academic anxiety negatively impacts students' performance and well-being. Although AI technologies are increasingly used in education, fin...

A randomised controlled trial comparing effectiveness of audio-visual aid and ai-personalised video self-modelling interventions to reduce dental fear and anxiety in paediatric patients.

PURPOSE: Paediatric dental anxiety remains a significant challenge in clinical practice, often impacting co-operation and treatment outcomes. This ran...

When attention falters: Brain, breathing, and behavioral signals of lapses in interoceptive attention.

Mind‑body practices, such as meditation and yoga, involve paying attention to breathing sensations. During these practices, individuals report "intero...

Assessment of global research trends on technological and AI-driven strategies for mitigating climate-induced heat stress based on 20 years bibliometric database.

Climate-induced heat stress has emerged as a serious global challenge due to rising temperatures, frequent heatwaves, and rapid urbanisation. These ch...