Rheumatology

Arthritis

Latest AI and machine learning research in arthritis for healthcare professionals.

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Next-Generation Bioelectric Medicine: Harnessing the Therapeutic Potential of Neural Implants.

Bioelectric medicine leverages natural signaling pathways in the nervous system to counteract organ dysfunction. This novel approach has potential to address conditions with unmet needs, including heart failure, hypertension, inflammation, arthritis, asthma, Alzheimer's disease, and diabetes. Neural therapies, which target the brain, spinal cord, or peripheral nerves, are already being applied to ...

Dec 16 2020 34476364

Population-Scale CT-based Body Composition Analysis of a Large Outpatient Population Using Deep Learning to Derive Age-, Sex-, and Race-specific Reference Curves.

Background Although CT-based body composition (BC) metrics may inform disease risk and outcomes, obtaining these metrics has been too resource intensive for large-scale use. Thus, population-wide distributions of BC remain uncertain. Purpose To demonstrate the validity of fully automated, deep learning BC analysis from abdominal CT examinations, to define demographically adjusted BC reference curv...

Nov 24 2020 33231527
Knee Acoustic Emissions as a Digital Biomarker of Disease Status in Juvenile Idiopathic Arthritis.

In this paper, we quantify the joint acoustic emissions (JAEs) from the knees of children with juvenile idiopathic arthritis (JIA) and support their u...

Nov 19 2020 34713044
Development of LC-MS/MS determination method and backpropagation artificial neural networks pharmacokinetic model of febuxostat in healthy subjects.

WHAT IS KNOWN AND OBJECTIVE: Febuxostat is a well-known drug for treating hyperuricemia and gout. The published methods for determination of febuxosta...

Nov 17 2020 33201513
Association of a Serum Protein Signature With Rheumatoid Arthritis Development.

OBJECTIVE: The pathophysiologic events that precede the onset of rheumatoid arthritis (RA) remain incompletely understood. This study was undertaken t...

Nov 10 2020 32770634
-Related Infections and their Significance: A 9-Year Retrospective Study.

INTRODUCTION: is a Gram-positive, catalase- and oxidase-negative, microaerophilic, nonmotile bacteria species rarely associated with human infections...

Nov 9 2020 33850708
Activity Prediction of Small Molecule Inhibitors for Antirheumatoid Arthritis Targets Based on Artificial Intelligence.

Rheumatoid arthritis (RA) is a chronic autoimmune disease, which is compared to "immortal cancer" in industry. Currently, SYK, BTK, and JAK are the th...

Nov 4 2020 33146518
Predictive Factors for Blood Transfusion after Total Knee Arthroplasty.

 The present paper aims to (1) verify the incidence and volume of blood transfusion among patients undergoing unilateral cemented total knee arthropl...

Nov 2 2020 34483390
Improving Quantitative Magnetic Resonance Imaging Using Deep Learning.

Deep learning methods have shown promising results for accelerating quantitative musculoskeletal (MSK) magnetic resonance imaging (MRI) for T2 and T1ρ...

Sep 29 2020 32992372
The optimisation of deep neural networks for segmenting multiple knee joint tissues from MRIs.

Automated semantic segmentation of multiple knee joint tissues is desirable to allow faster and more reliable analysis of large datasets and to enable...

Sep 28 2020 33075675
Deep Learning in Gait Parameter Prediction for OA and TKA Patients Wearing IMU Sensors.

Quantitative assessments of patient movement quality in osteoarthritis (OA), specifically spatiotemporal gait parameters (STGPs), can provide in-depth...

Sep 28 2020 32998329
Enabling early detection of osteoarthritis from presymptomatic cartilage texture maps via transport-based learning.

Many diseases have no visual cues in the early stages, eluding image-based detection. Today, osteoarthritis (OA) is detected after bone damage has occ...

Sep 21 2020 32958644
An Artificial Neural Network Model for Assessing Frailty-Associated Factors in the Thai Population.

Frailty, one of the major public health problems in the elderly, can result from multiple etiologic factors including biological and physical changes ...

Sep 18 2020 32961919
Imaging of OA - From disease modification to clinical utility.

Multiple disease-modifying osteoarthritis drug (DMOAD) trials were done in the last two decades, but no pharmacological agent has yet been approved by...

Sep 15 2020 32943330
Genomic risk scores for juvenile idiopathic arthritis and its subtypes.

OBJECTIVES: Juvenile idiopathic arthritis (JIA) is an autoimmune disease and a common cause of chronic disability in children. Diagnosis of JIA is bas...

Sep 4 2020 32887683
ANTIPROLIFERATIVE PROPERTIES OF ETHANOLIC AND AQUEOUS GRAVIOLA LEAF EXTRACTS ON TONGUE SQUAMOUS CELL CARCINOMA CELL LINE-25.

BACKGROUND: commonly known as Graviola, soursop or guanabana, is an evergreen tree native to the tropics with a long history of use in ethnomedicine ...

Aug 21 2020 34337375
Applications of Artificial Intelligence in Musculoskeletal Imaging: From the Request to the Report.

Artificial intelligence (AI) will transform every step in the imaging value chain, including interpretive and noninterpretive components. Radiologists...

Aug 18 2020 32809857
Digital health technologies: opportunities and challenges in rheumatology.

The past decade in rheumatology has seen tremendous innovation in digital health technologies, including the electronic health record, virtual visits,...

Jul 24 2020 32709998
Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients.

Baricitinib is an oral Janus kinase (JAK)1/JAK2 inhibitor approved for the treatment of rheumatoid arthritis (RA) that was independently predicted, us...

Jun 24 2020 32473600
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