Arthritis

Precision Transfusion Medicine in the Omics Era.

Transfusion medicine has practiced a form of precision medicine for decades through compatibility testing, infectious disease screening, component manufacturing, traceability, and hemovigilance. Yet blood is still often treated primarily as a commodity, collected, processed, stored, and transfused, rather than as a dynamic biologic product rich in molecular information. This Perspective argues tha...

AI-based CT quantification reveals small airway loss and vascular simplification in rheumatoid arthritis-associated lung disease.

OBJECTIVES: To investigate pulmonary structural changes in patients with rheumatoid arthritis (RA) using an artificial intelligence (AI)-based CT segmentation model and evaluate the diagnostic potential of quantitative imaging biomarkers. METHODS: This cross-sectional study included 556 non-smoking RA patients and 472 non-smoking healthy controls. An AI-based CT segmentation model was used to quan...

Computational intelligence using nailfold videocapillaroscopy for the prediction of carotid intima-media thickness in rheumatoid arthritis: a cohort-based study.

Despite continuously evolving medical advances, CVD risk in Rheumatoid Arthritis (RA) remains paradoxically high to date. Carotid intima-media thickne...

Immunoglobulin Heavy Constant Mu as a Shared Gene in Periodontitis and Rheumatoid Arthritis: A Bioinformatic Analysis.

INTRODUCTION AND AIMS: Rheumatoid arthritis (RA) and periodontitis (PD) are two inflammatory diseases sharing immunopathogenic features and a common i...

Identifying predictor factors for asthma using machine learning: evidence from the English Longitudinal Study of Ageing.

BACKGROUND: Asthma is a common chronic inflammatory airway disease. Accumulating evidence highlights the roles of demographic, lifestyle, and comorbid...

Identification and validation of novel diagnostic biomarkers across multiple tissues in osteoarthritis.

BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease characterized by synovial inflammation, cartilage degradation, and subchondral bone re...

Processed meat intake and incident gout: Integrated evidence from epidemiology, plasma proteomics, and machine learning.

INTRODUCTION: Gout is a common metabolic inflammatory disorder whose incidence parallels modern dietary shifts. Although processed meat intake is link...

MMP9 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced osteoarthritis cartilage damage via regulating the p38 MAPK pathway: A mechanistic study based on network toxicology and multi-omics.

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a highly toxic persistent organic pollutant (POP), is associated with musculoskeletal disorders, yet its m...

Identification and Experimental Verification of Key Genes Related to the Ras Signaling Pathway and the Hippo Signaling Pathway in Osteoarthritis Based on Transcriptome Data.

BACKGROUND: Osteoarthritis (OA) is a chronic degenerative joint disease characterized by the progressive deterioration of articular cartilage, signifi...

Early prediction of joint space narrowing in rheumatoid arthritis using AI-quantified bilateral joint space asymmetry on hand radiography.

PURPOSE: Joint space narrowing (JSN) in rheumatoid arthritis (RA) can progress even during clinical remission. Conventional imaging lacks sensitivity ...

Psoriatic Disease Across Dimensions: Global Epidemiology, Comorbidity, and Artificial Intelligence in Treatment Prediction.

The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2025 annual meeting featured a new "Soapbox: Rapid fire presentati...

BHOD: a bone health optimized dietary pattern designed for osteoporosis prevention.

Existing dietary patterns were not specifically designed to target osteoporosis and lack the precision required for effective prevention. We aimed to ...

AI-assisted Radiomic Model for Cervical Cancer Recurrence Prediction: A Multicenter Retrospective Study with Experimental Validation.

Purpose To evaluate the value of a nomogram model incorporating clinical parameters, hematologic inflammatory biomarkers, and MRI radiomic features in...

Review of the SWIR Windows to Study Osteoarthritis.

Due to minimal absorption and scattering, light at select wavelengths in the short wavelength infrared (SWIR: 1000-2500 nm) region can be utilized for...

Integrative Genomic and Clinical Profiling of Colorectal Cancer Liver Metastases to Guide Personalized Surgery and Liver Transplantation.

BACKGROUND/AIM: Colorectal cancer liver metastases (CRLM) remain a leading cause of cancer-related mortality. Although hepatic resection is the only e...

Elucidating the mechanism of taurine in alleviating osteoarthritis progression based on bioinformatics, machine learning algorithm, and experimental validation.

BACKGROUND: Ferroptosis, a form of regulated cell death driven by iron-dependent lipid peroxidation, plays a pivotal role in chondrocyte death and the...

Artificial intelligence in rheumatology: a cross-sectional Scopus-based analysis.

Artificial intelligence (AI) is increasingly used in clinical medicine. Rheumatology is well-suited to AI applications due to diagnostic complexity of...

Artificial intelligence (AI)-assisted diagnosis of skin diseases: From image classification to dermatology-specific multimodal clinical reasoning.

Artificial intelligence (AI) in dermatology has moved beyond the early paradigm of single-image classification. Dermatological diagnosis is achieved b...

Identification of distinct subgroups in Chinese patients with Behçet's syndrome via cluster analysis of immune cells and clinical features.

OBJECTIVES: This study aimed to use machine learning to explore Behçet's syndrome (BS) heterogeneity by integrating immunocyte subpopulations and clin...

Deep learning-based effusion-synovitis volume measured on MRI is associated with osteoarthritis progression: A longitudinal analysis of data from the osteoarthritis initiative.

OBJECTIVE: To investigate whether the 48-month change in effusion-synovitis volume (ΔESV) is associated with concurrent knee osteoarthritis progressio...