Rheumatology

Arthritis

Latest AI and machine learning research in arthritis for healthcare professionals.

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Showing 121-140 of 2,542 articles

Unsupervised Machine Learning of Inflammatory Bowel Disease Case Reports Reveals Decades of Evolving Research Themes.

BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) case reports provide rich longitudinal insights but have rarely been analyzed using quantitative text-mining approaches. This study applied unsupervised machine learning to PubMed-indexed IBD case reports to identify long-term thematic structures spanning 60 years and evaluate whether major historical milestones in IBD care can be reconstructed...

Jun 27 2026 42365648

The functional relevance of human leukocyte antigens in the development of cord blood derived advanced cellular therapies: A new direction of public cord blood banks.

CBUs have been applied as alternative source of HSCs transplantation. The increasing preference for haploidentical HSC transplantation has resulted in a reduced application of CBUs worldwide. Banked CBUs in public CBBs have been processed with the highest quality standards, representing a valuable biologic source for potential production of ATMPs. The aim of this study was to characterize the HLA ...

Jun 27 2026 42364409
Corneal nerve regeneration: treatments and monitoring approaches.

BACKGROUND: Diagnostics and therapeutics for corneal nerve pathologies are rapidly evolving, with continual advancements in imaging, laser, machine le...

Jun 25 2026 42343826
Programmed cell death-related gene S100A9 promotes macrophage M1 polarization and chondrocyte apoptosis in rheumatoid arthritis.

BACKGROUND: Rheumatoid arthritis (RA) is a heterogeneous chronic autoimmune disease. Its high disability rate has a serious impact on individuals and ...

Jun 25 2026 42351193
An intelligent point-of-care photoacoustic and ultrasound dual-modality imaging system for Rheumatoid arthritis in fingers: Technical development and initial clinical test.

Aiming at an intelligent point-of-care imaging technology for rheumatology clinics, a fully automatic 3D photoacoustic (PA) and ultrasound (US) dual-m...

Jun 24 2026 42389548
Identification of a 10-protein plasma signature for preclinical gout risk beyond serum urate: a robustness-first proteomic study in 33,147 normouricaemic individuals.

BACKGROUND: Gout risk assessment is currently reactive, relying on hyperuricaemia. However, a significant clinical gap exists for individuals who deve...

Jun 24 2026 42343390
Identification of Diagnostic Biomarkers Among Metabolism-related Genes in Rheumatoid Arthritis: Insights into Immune Landscape and Molecular Subtype Characterization.

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and joint destruction. Metabolic reprogramming and im...

Jun 24 2026 42340574
Effects of biologic and targeted synthetic disease modifying antirheumatic drugs (b/tsDMARDs) on patient-reported outcome domains in rheumatoid arthritis: a systematic review and network meta-analyses.

INTRODUCTION: Evidence from head-to-head comparisons of biologic/targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) on patient-repo...

Jun 24 2026 42342282
Identification of small-molecule TNF-α inhibitor candidates using machine learning-guided screening and multiscale molecular modelling.

Lumbar disc herniation (LDH) is a major cause of chronic low back pain, in which tumor necrosis factor-alpha (TNF-α) plays a central role in inflammat...

Jun 24 2026 42342749
Combining Network Pharmacology, Machine Learning, Molecular Docking, and Experimental Validation to Explore the Mechanism of Danggui-Shaoyao-San in treating Rheumatoid arthritis.

BACKGROUND: Danggui-Shaoyao-San (DSS) demonstrates clinical efficacy in rheumatoid arthritis (RA), but its bioactive constituents and molecular mechan...

Jun 23 2026 42337901
Natural language processing to enhance rheumatoid arthritis care in clinical studies: a scoping review of applications, data, approaches, challenges and future directions.

Structured claims or EMR datasets have limitations, such as lacking important clinical variables, upcoding, or potential coding errors. Unstructured d...

Jun 22 2026 42329422
Development of Data-Driven Models for Just-in-Time Digital Self-Management Advice to Improve Physical Functioning in Hip and Knee Osteoarthritis: Protocol for the e-cOAch Cross-Over Study.

BACKGROUND: Clinical guidelines recommend a stepped-care strategy for patients with hip and knee osteoarthritis that begins with nonoperative approach...

Jun 22 2026 42330486
Deep Learning-based Quantification of Knee Effusion-Synovitis Volume on MRI - Technique Development and Validation.

OBJECTIVE: To develop and validate a deep learning (DL) model for automatic quantification of knee effusion-synovitis volume (ESV) on MRI, assess corr...

Jun 22 2026 42331136
Detection of rheumatoid arthritis-associated interstitial lung disease: a systematic review and meta-analysis.

BACKGROUND: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) often has an insidious onset with few or no respiratory symptoms, so ea...

Jun 22 2026 42324528
Multidimensional immunoinflammatory profiles associated with rheumatoid arthritis-associated interstitial lung disease: a cross-sectional exploratory study.

OBJECTIVE: To investigate the associations of non-invasive peripheral blood inflammatory indices, cytokines, and lymphocyte subsets with the risk of r...

Jun 20 2026 42322541
Optimising biologic therapy in psoriasis: dose adjustment, treatment duration, and tapering-an expert perspective.

INTRODUCTION: Biologic therapies have transformed the management of moderate-to-severe psoriasis; however, long-term treatment requires optimization s...

Jun 20 2026 42323205
Prognostic prediction models for psoriatic arthritis in psoriasis: A systematic review.

BACKGROUND: Psoriatic arthritis is a chronic inflammatory arthropathy that affects up to 22% of individuals with psoriasis. Identifying patients at hi...

Jun 18 2026 42312903
Toward Cost-efficient Adaptive Clinical Trials in Knee Osteoarthritis with Reinforcement Learning.

Osteoarthritis (OA) is the most common musculoskeletal disease, with knee OA (KOA) being one of the leading causes of disability and a significant eco...

Jun 18 2026 42313597
Factors Associated With an LLM Arriving at the Same Diagnosis as a Musculoskeletal Specialist.

INTRODUCTION: Large language models (LLMs) can generate plausible diagnoses from patient symptom descriptions and convey complex medical information i...

Jun 17 2026 42299823
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