Cardiovascular

Atherosclerosis

Latest AI and machine learning research in atherosclerosis for healthcare professionals.

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Showing 381-400 of 5,172 articles

Development and validation of a novel deep learning coronary artery plaque quantification model.

BACKGROUND: Coronary Computed Tomography Angiography (CCTA) is an established tool for assessing coronary artery disease. CCTA determined total coronary artery plaque volume predicts cardiovascular events, but manual quantification is impractical for routine use. Deep learning-based methods offer a promising solution for automated plaque volume assessment. METHODS: We developed and validated a nov...

May 14 2026 42135689

Non-traditional metabolic indices predict incident circadian syndrome in middle-aged and older Chinese adults: a nationwide prospective cohort study and machine learning analysis.

BACKGROUND: Circadian syndrome (CircS) augments the conventional metabolic syndrome construct by adding disturbed sleep and depressive features. Whether composite metabolic indices that combine insulin-resistance, atherogenic-lipid, and inflammatory signals can forecast CircS prior to its onset has not been systematically investigated. The present work evaluated eight such composite markers in a p...

May 13 2026 42129743
Predicting anemia treatment outcomes in maintenance hemodialysis patients using multiple machine learning models.

BACKGROUND: Based on machine learning prediction models, we explored the anemia treatment attainment of patients on maintenance hemodialysis (MHD) and...

May 13 2026 42129786
Cellular Senescence as a Systems-Level Driver of Cardiovascular Ageing.

Cellular senescence is increasingly recognized as a fundamental driver of cardiovascular ageing; however, its molecular heterogeneity, cell-type speci...

May 13 2026 42134737
Machine learning for risk stratification of postoperative corneal edema in East Asian cataract patients: a model for precision ophthalmology.

PURPOSE: To develop and validate machine learning (ML) models for predicting early postoperative corneal edema (CE) after phacoemulsification in patie...

May 13 2026 42126536
High scan-rescan repeatability of AI-enabled coronary plaque quantification from coronary CT angiography.

OBJECTIVES: To evaluate the reproducibility of plaque quantification from serial cardiac computed tomography (CCTA) scans by a systematic side-by-side...

May 12 2026 42120754
Real-world insights into coronary CTA prognostication: value of semiquantitative scores.

PURPOSE: Several semiquantitative coronary computed tomography angiography (CCTA) scores including different parameters describing stenosis degree, pl...

May 12 2026 42118201
Molecular mechanism leading to human coronary atherosclerosis assessed by proteomic analysis and RNA sequences.

BACKGROUND AND AIMS: Atherosclerosis results from cellular and extracellular changes in the arterial wall, preceded by molecular shifts that initiate ...

May 12 2026 42119148
Dissecting the pathobiology of suspected sepsis through a comparative analysis of endothelial inflammatory and clinical prediction models.

Sepsis remains a formidable challenge in critical care, and is characterized by profound circulatory and cellular abnormalities driven by both systemi...

May 12 2026 42120425
Development and validation of a digital biomarker for peripheral artery disease.

Peripheral artery disease (PAD) is a common manifestation of atherosclerotic cardiovascular disease (ASCVD) that is underdiagnosed in clinical practic...

May 12 2026 42120557
Machine learning-based prediction of diabetic retinopathy using clinlabomics: a multi-center study.

BACKGROUND: Diabetic retinopathy (DR) is a leading cause of vision loss, yet conventional retinal screening remains costly and resource-intensive. Thi...

May 11 2026 42116016
A TyG-UHR-based machine learning model for screening lean MAFLD: development and external validation.

BACKGROUND: Lean metabolic dysfunction-associated fatty liver disease (MAFLD) is increasingly recognized but often goes unnoticed during health checku...

May 11 2026 42116045
Cardiovascular Risk Stratification in Youth-Onset Type 2 Diabetes Using Machine Learning.

BACKGROUND: The rising incidence of youth-onset type 2 diabetes mellitus (T2DM), along with the risk of early cardiovascular complications, is concern...

May 11 2026 42117144
Mechanisms driving thoracic aortic aneurysm instability.

Thoracic aortic aneurysms arise from a combination of biological and mechanical factors. Current clinical guidelines use size and rate of expansion to...

May 11 2026 42113285
Single-cell profiling identifies a pro-tumoral VCAN positive macrophage subset and defines a prognostic signature in glioblastoma.

Glioblastoma (GBM), the most aggressive primary brain tumor, develops within a tumor microenvironment (TME) dominated by tumor-associated macrophages ...

May 9 2026 42105040
SPISE index and ensemble machine learning refine cardiovascular risk stratification in stage 0-3 CKM syndrome.

BACKGROUND: While the single-point insulin sensitivity estimator (SPISE) shows promise as an insulin resistance biomarker, its association with cardio...

May 8 2026 42101474
From Lumen to Myocardium With Artificial Intelligence: A Clinician's Guide to Comprehensive Cardiac CT.

Coronary artery disease assessment has long focused on stenosis severity, yet luminal narrowing alone fails to capture ischemic burden, plaque vulnera...

May 8 2026 42101950
Development and external validation of an interpretable machine-learning model for HFpEF comorbidity risk in COPD patients.

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) and Heart Failure with preserved Ejection Fraction (HFpEF) frequently coexist, leading to inc...

May 8 2026 42104441
DIGITAL TECHNOLOGIES FOR DENTAL PLAQUE ASSESSMENT: A SYSTEMATIC REVIEW AND META-ANALYSIS OF CORRELATION COEFFICIENTS.

OBJECTIVES: This systematic review and meta-analysis aimed to evaluate the strength of the associations between digital technologies and reference met...

May 7 2026 42556893
Spermidine suppresses liver fibrosis by remodeling the communication signal between liver sinusoidal endothelial cells and hepatic stellate cells.

Hepatic fibrosis is a pivotal stage in which chronic liver disease progresses from reversible injury to decompensation. Liver sinusoidal endothelial c...

May 7 2026 42098063
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