Cardiovascular

Atherosclerosis

Latest AI and machine learning research in atherosclerosis for healthcare professionals.

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Coronary CT angiography evaluation with artificial intelligence for individualized medical treatment of atherosclerosis: a Consensus Statement from the QCI Study Group.

Coronary CT angiography is widely implemented, with an estimated 2.2 million procedures in patients with stable chest pain every year in Europe alone. In parallel, artificial intelligence and machine learning are poised to transform coronary atherosclerotic plaque evaluation by improving reliability and speed. However, little is known about how to use coronary atherosclerosis imaging biomarkers to...

Aug 1 2025 40751112

Pre-interventional transesophageal echocardiography as a reliable predictor of residual shunt following patent foramen ovale closure.

BACKGROUND: Closure of a patent foramen ovale (PFO) is an effective strategy in the prevention of recurrent stroke after cryptogenic stroke. Residual shunt (RS) is a common issue following PFO closure and may affect safety and efficacy. Transesophageal echocardiography (TEE) is the key diagnostic tool, but standardized assessment of morphological parameters to prevent RS remains challenging. AIMS:...

Jul 24 2025 40705044
Emerging innovations in ophthalmic drug delivery for diabetic retinopathy: a translational perspective.

Diabetic retinopathy (DR) is a progressive microvascular complication of diabetes and a leading cause of vision impairment worldwide. Despite advancem...

Jul 20 2025 40685494
Incidental Finding of Coronary and Non-Coronary Artery Calcium: What Do Clinicians Need To Know?

PURPOSE OF REVIEW: This review summarizes the role of incidentally and non-incidentally discovered coronary artery calcification (CAC) and the evolvin...

Jul 12 2025 40650862
Development and validation of a prognostic model for predicting survival and immunotherapy benefits in melanoma based on metabolism-relevant genes.

Skin cutaneous melanoma (SKCM) is a fatal form of skin cancer. Metabolism-related genes (MRGs) comprise a group of genes that possess the ability to m...

Jul 12 2025 40652057
Identification of diagnostic biomarkers and dissecting immune microenvironment with crosstalk genes in the POAG and COVID-19 nexus.

An underlying association between primary open-angle glaucoma (POAG) and COVID-19 has been hypothesized, but the causal link and shared mechanisms rem...

Jul 12 2025 40652070
Screening and investigating the regulatory mechanisms of oxidative stress-related biomarkers in thoracic aortic aneurysms.

Excess reactive oxygen species leading to oxidative stress has been identified as a significant factor in cardiovascular disease. However, the molecul...

Jul 11 2025 40643772
Modelling key ecological factors influencing the distribution and content of silymarin antioxidant in Silybum marianum L.

The increasing demand for natural medicine has increased the significance of Silybum marianum as a valuable medicinal plant. It is used to restore liv...

Jul 11 2025 40644415
Exploration and validation of the prognostic value of mitophagy and mitochondrial dynamics-related genes in cervical cancer.

The mechanisms underlying mitophagy and mitochondrial dynamics (MD) in cervical cancer (CC), a disease with a high mortality rate, remain poorly under...

Jul 10 2025 40640353
Inflammatory, fibrotic and endothelial biomarker profiles in COVID-19 patients during and following hospitalization.

Survivors of severe COVID-19 often suffer from long-term respiratory issues, but the molecular drivers of this damage remain unclear. This study explo...

Jul 10 2025 40640381
Automated Laser Modified EndoGraft (ALMEG).

OBJECTIVES: To describe the technical details of a new and innovative method for modifying endografts to treat complex aortic aneurysms, especially in...

Jul 7 2025 40624798
Machine learning identifies KRT8 dysregulation and endothelial remodeling in Moyamoya disease.

Moyamoya disease (MMD) is a rare occlusive cerebrovascular disease, and its pathological mechanism remains unclear at present. The abnormal vascular r...

Jul 7 2025 40624255
Predictive modeling and machine learning show poor performance of clinical, morphological, and hemodynamic parameters for small intracranial aneurysm rupture.

Small intracranial aneurysms (SIAs) (< 5 mm) are increasingly detected due to advanced imaging, but predicting rupture risk remains challenging. Ruptu...

Jul 5 2025 40617943
Early transcriptional responses reveal cell type-specific vulnerability and neuroprotective mechanisms in the neonatal ischemic hippocampus.

Neonatal hypoxic-ischemic (H-I) brain injury, a leading cause of neurodevelopmental disabilities, severely affects the metabolically active and neurog...

Jul 5 2025 40618091
Novel CAC Dispersion and Density Score to Predict Myocardial Infarction and Cardiovascular Mortality.

BACKGROUND: Coronary artery calcification (CAC) provides robust prediction for major adverse cardiovascular events (MACE), but current techniques disr...

Jul 4 2025 40613107
Quantitative CT Imaging in Chronic Obstructive Pulmonary Disease.

Chronic obstructive pulmonary disease (COPD) is a highly heterogeneous condition characterized by diverse pulmonary and extrapulmonary manifestations....

Jul 4 2025 40613687
Predicting carotid atherosclerosis in latent autoimmune diabetes in adult patients using machine learning models: a retrospective study.

BACKGROUND: Latent autoimmune diabetes in adults (LADA) is a slowly progressing form of diabetes with autoimmune origins. Patients with LADA are at an...

Jul 3 2025 40610930
Network-based machine learning reveals cardiometabolic multimorbidity patterns and modifiable lifestyle factors: a community-focused analysis of NHANES 2015-2018.

Cardiometabolic Multimorbidity (CMM) has emerged as one of the primary threats to human health globally due to its high incidence, disability, and mor...

Jul 3 2025 40610956
Deep learning framework for cardiorespiratory disease detection using smartphone IMU sensors.

Respiratory and cardiovascular diseases represent a significant global health burden, underscoring the need for innovative, accessible, and cost-effec...

Jul 3 2025 40614516
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