Cardiovascular

Atherosclerosis

Latest AI and machine learning research in atherosclerosis for healthcare professionals.

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Showing 761-780 of 5,364 articles

Association between atherogenicity indices and prediabetes: a 5-year retrospective cohort study in a general Chinese physical examination population.

BACKGROUND AND OBJECTIVE: Atherogenicity indices have emerged as promising markers for cardiometabolic disorders, yet their relationship with prediabetes risk remains unclear. This study aimed to comprehensively evaluate the associations between six atherogenicity indices and prediabetes risk in a Chinese population, and explore the predictive value of these atherosclerotic parameters for prediabe...

May 21 2025 40399916

Intercellular communication in the brain via dendritic nanotubular network.

Recent studies have identified intercellular networks for material exchange by bridge-like nanotubular structures, yet their existence in neurons remains unexplored within the brain. Here, we identified long, thin dendritic filopodia that establish direct dendrite-to-dendrite contacts, forming dendritic nanotubes (DNTs) in mammalian brains. Using super-resolution microscopy, we characterized their...

May 21 2025 40475405
Associations of the Hs-CRP/HDL-C ratio with stroke among US adults: Evidence from NHANES 2015-2018.

BACKGROUND: The high-sensitivity C-reactive protein (Hs-CRP)-to-high-density lipoprotein cholesterol (HDL-C) ratio, which integrates insights into inf...

May 20 2025 40404075
Integrating Artificial Intelligence and Precision Therapeutics for Advancing the Diagnosis and Treatment of Age-Related Macular Degeneration.

Age-related macular degeneration (AMD) is a multifactorial retinal disease influenced by complex molecular mechanisms, including genetic susceptibilit...

May 20 2025 40428167
Contemporary Prevention and Management of Postoperative Delirium in Cardiac Surgery Patients.

This review examines the prevention and management of postoperative delirium in cardiac surgery patients, a frequent complication linked with signific...

May 19 2025 40398532
Layer-Specific Colocalization of Microglia with Amyloid Plaques in the Middle Temporal Gyrus Predicts Cognitive Decline in Alzheimer's Disease.

Alzheimer's disease (AD), the most common form of dementia, is marked by cognitive decline and amyloid-beta (Aβ) plaque deposition in the brain. Micro...

May 19 2025 40423635
Study on Liver Sinusoidal Endothelial Cell Fenestrations Based on Cellular Omics-Structure Integration Technology and Its Application in Metabolic Diseases.

This study developed a new Cellular Omics-Structural Integration (COSI) technology platform to address the limitation of traditional technologies in s...

May 19 2025 40475559
Cardiovascular imaging in 2024: review of current research and innovations.

Cardiovascular imaging saw significant advancements in 2024, impacting technology, pathophysiology, and clinical applications. This review provides a ...

May 17 2025 40469529
High-Resolution Spatial Profiling of Microglia Reveals Proximity Associated Immunometabolic Reprogramming in Alzheimer's Disease.

Single-cell RNA sequencing has demonstrated that the presence of parenchymal amyloid plaques and intracellular hyperphosphorylated tau pathology is as...

May 16 2025 40462993
Nucleic acid spheres for treating capillarisation of liver sinusoidal endothelial cells in liver fibrosis.

Liver sinusoidal endothelial cells (LSECs) lose their characteristic fenestrations and become capillarized during the progression of liver fibrosis. M...

May 15 2025 40374623
Direct evaluation of antiplatelet therapy in coronary artery disease by comprehensive image-based profiling of circulating platelets.

Coronary artery disease (CAD) is a leading cause of death globally. Antiplatelet therapy remains crucial in preventing and treating CAD-associated thr...

May 15 2025 40374642
Circulating fibroblast growth factor 21 is associated with blood pressure in the Chinese population: a community-based study.

BACKGROUND: Our research team previously found that fibroblast growth factor (FGF) 21, a circulating hormone, was significantly associated with athero...

May 12 2025 40356318
Serum sclerostin as a marker of microvascular and macrovascular complications among children and adolescents with type 1 diabetes mellitus.

BACKGROUND: Uncontrolled diabetes mellitus (DM) accelerates atherosclerosis and vascular diseases, leading to micro- and macrovascular complications. ...

May 12 2025 40353858
Multi-centric AI Model for Unruptured Intracranial Aneurysm Detection and Volumetric Segmentation in 3D TOF-MRI.

The aim of this study was to develop an open-source nnU-Net-based AI model for combined detection and segmentation of unruptured intracranial aneurysm...

May 12 2025 40355691
Switching Therapy to the Second Brand of Generic Atorvastatin: A 6-Month Retrospective Cohort, Real-World Study.

INTRODUCTION: High levels of low-density lipoprotein-cholesterol (LDL) is a major risk factor for cardiovascular diseases. While treatment with atorva...

May 11 2025 40349283
An All-in-one Nanohole Array for Size-Exclusive Trapping and High-Throughput Digital Counting of Single Extracellular Vesicles for Non-invasive Cancer Screening.

The analysis of single small extracellular vesicles (sEVs) could distinguish the heterogeneity of sEVs thus better extract tumor-related signatures. C...

May 11 2025 40350375
Iron-dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP-1 monocytes.

Atherosclerosis leading to cardiovascular diseases remains a dominant medical problem. In the early stages of this disease, the interaction between ci...

May 11 2025 40350792
Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib.

Fruquintinib (FRUZAQLA) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (-1, -2, and -3). Tw...

May 10 2025 40346878
Preoperative BOLD cerebrovascular reactivity correlates with intraoperative STA-MCA bypass flow and influences postoperative CVR improvement.

INTRODUCTION: The superficial temporal artery-middle cerebral artery (STA-MCA) flow augmentation bypass is effective for treating Moyamoya vasculopath...

May 10 2025 40347485
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