Atherosclerosis

Bibliometric analysis of research hotspots in coronary artery CT fractional flow reserve for diagnosing myocardial ischemia in coronary artery disease.

OBJECTIVE: This study aimed to conduct a comprehensive bibliometric analysis to map the global research landscape, identify evolving hotspots, and forecast future trends in the application of coronary computed tomography-derived fractional flow reserve (CT-FFR) for diagnosing myocardial ischemia in coronary artery disease (CAD). METHODS: A systematic literature search was performed in the Web of S...

Screening of atherosclerosis diagnostic markers based on lymphangiogenesis-related genes and analysis of immunological characteristics.

BACKGROUND: Atherosclerosis (AS) was a major cause of cardiovascular disease, and traditional diagnostic methods often fail to detect AS promptly and accurately. Formation of new lymphatic vessels, or lymphangiogenesis, is a crucial process in the development of many diseases. However, the value of lymphangiogenesis-related genes (LRGs) as potential diagnostic markers for AS remained incompletely ...

Coronary computed tomography angiography to guide percutaneous coronary intervention: proceedings from the 1st CCTA-guided PCI summit in the United States.

Coronary computed tomography angiography (CCTA) can be used beyond diagnostic purposes to support the preprocedural planning of percutaneous coronary ...

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and the characteristics of carotid artery plaques: a retrospective study and machine learning model construction.

BACKGROUND: Low-echo plaques are closely related to stroke. Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NH...

Machine learning derived abdominal aortic calcification is associated with physical frailty in community-dwelling adults: the UK Biobank Imaging Study.

Clinical cardiovascular disease (CVD) is often present in frail individuals. However, it remains unclear whether subclinical CVD, e.g., abdominal aort...

Interpretability of multimodal neural networks for prediction of visual acuity in patients with branch retinal vein occlusion.

Branch retinal vein occlusion (BRVO) can cause persistent visual impairment, and predicting long-term best-corrected visual acuity (BCVA) after anti-v...

Cardiometabolic multimorbidity and atrial fibrillation: insights from traditional statistical and artificial intelligence approaches.

BACKGROUND: Cardiometabolic multimorbidity (CMM) is increasingly prevalent among patients with atrial fibrillation (AF), yet its independent impact on...

Single-cell RNA sequencing in ovarian cancer: decoding the tumor microenvironment for personalized therapy.

Ovarian cancer (OC) remains a leading cause of mortality among gynecological malignancies, largely due to profound inter- and intra-tumoral heterogene...

Decoding the Genetic Architecture of Acute Coronary Syndrome: A Review on Integrated Medical Modeling.

UNLABELLED: Genetic mutations contribute significantly to the complexity of understanding Acute Coronary Syndrome (ACS). Artificial Intelligence (AI) ...

Targeting the Myocardial Microenvironment: Novel Antiviral Strategies and Therapeutic Perspectives for Coxsackievirus B-Induced Myocarditis.

Coxsackievirus B3 is a primary cause of viral myocarditis, with ≈20% of cases progressing to dilated cardiomyopathy. Despite its clinical significance...

Super learner model for predicting carotid plaque regression in type 2 diabetes on PCSK9 inhibitors.

OBJECTIVES: Evidence regarding the effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on carotid plaque regression in patient...

EMBC Special Issue: Non-invasive BP Estimation via Carotid-Brachial-Radial Coupling: A Physics-Informed Asymmetric Cycle Network Approach.

Photoplethysmogram (PPG) based cuffless blood pressure (BP) monitoring holds significant potential to revolutionize hypertension management. However, ...

Trusting Generative AI for Health Advice: Preregistered Survey Experiment.

BACKGROUND: Generative artificial intelligence (AI) systems are increasingly used for health information seeking, yet it remains unclear how the publi...

Burden trajectories of stroke attributable to lipid-glucose dysfunction and biomarker validation: evidence from the global burden of disease (GBD) 2023 and the China health and retirement longitudinal study (CHARLS).

BACKGROUND: Metabolic dysfunction is an important contributor to stroke burden and may also help identify individuals at higher future risk of stroke....

Contrastive Machine Learning to Quantify Hypertensive Multiorgan Damage and Identify New Disease Phenotypes: A Multinational Multimodal Study.

BACKGROUND: Hypertension induces structural and functional damage in multiple organs. Evidence of subclinical damage increases risk of vascular events...

Integrating epidemiological and transcriptomic data reveals novel lipid metabolic drivers of obstructive sleep apnea.

BACKGROUND: Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep and is frequently accompanied by dyslipi...

Identifying Patients at Elevated Risk of Stroke After.

BACKGROUND: Transcarotid artery revascularization (TCAR) has assumed a significant role in the surgical treatment of extracranial carotid occlusive di...

A machine learning-based framework for predicting hypertension using serum hematological factors.

Hypertension (HTN) is a leading global cause of cardiovascular disease (CVD) and all-cause mortality, underscoring the need for early detection and in...

Association between visceral adiposity index and delayed union/nonunion after tibial or femoral shaft fractures: a single-center retrospective cohort study.

BACKGROUND: Delayed union and nonunion remain clinically important complications after tibial and femoral shaft fractures. Although traditional risk f...

Integrating 2.5D multi-modal CT imaging with serum triglycerides for early risk stratification in hypertriglyceridemia-induced acute pancreatitis: A multicenter study.

OBJECTIVES: To develop and externally validate a clinical-radiological framework that fuses 2.5D deep learning features from dual-phase computed tomog...