Atherosclerosis

Biofilm architecture and dynamics of the oral ecosystem.

The oral cavity, being a nutritionally enriched environment, has been proven to be an ideal habitat for biofilm development. Various microenvironments, including dental enamel, supra- and subgingival surfaces, salivary fluid, and the dorsal surface of the tongue, harbor diverse microbes. These biofilms typically consist of four major layers. Depending on the food, age, clinical state, and lifestyl...

Deep learning and radiomics-based vascular calcification characterization in dental cone beam computed tomography as a predictive tool for cardiovascular disease: a proof-of-concept study.

OBJECTIVES: This study evaluated an automated deep learning method for detecting calcifications in the extracranial and intracranial carotid arteries and vertebral arteries in cone beam computed tomography (CBCT) scans. Additionally, a model utilizing CBCT-derived radiomics imaging biomarkers was evaluated to predict the cardiovascular diseases (CVD) of stroke and heart attack.

Actuation-Mediated Compression of a Mechanoresponsive Hydrogel by Soft Robotics to Control Release of Therapeutic Proteins.

Therapeutic proteins, the fastest growing class of pharmaceuticals, are subject to rapid proteolytic degradation in vivo, rendering them inactive. Sop...

Evaluation of a machine learning-based metabolic marker for coronary artery disease in the UK Biobank.

BACKGROUND AND AIMS: An in silico quantitative score of coronary artery disease (ISCAD), built using machine learning and clinical data from electroni...

Radiomics and deep learning features of pericoronary adipose tissue on non-contrast computerized tomography for predicting non-calcified plaques.

BACKGROUND: Inflammation of coronary arterial plaque is considered a key factor in the development of coronary heart disease. Early the plaque detecti...

Cytotoxicity, Antiadipogenic, Low-Density Lipoprotein Oxidation Inhibitory Activities, and Acute Toxicity Study of Hydroethanolic Leaf and Bark Extracts.

Obesity is increasingly taking an important stage as a cause of death worldwide, and interventions with a good cost-effectiveness ratio are needed. ...

Artificial intelligence-derived coronary artery calcium scoring saves time and achieves close to radiologist-level accuracy accuracy on routine ECG-gated CT.

Artificial Intelligence (AI) has been proposed to improve workflow for coronary artery calcium scoring (CACS), but simultaneous demonstration of impro...

Individual risk assessment for rupture of abdominal aortic aneurysm using artificial intelligence.

OBJECTIVE: This study aimed to develop a prediction tool to identify abdominal aortic aneurysms (AAAs) at increased risk of rupture incorporating demo...

Onset and long-term duration of immunity provided by a single vaccination with recombinant a Marek's disease virus with REV-LTR insertion.

Marek's Disease (MD), caused by Marek's disease virus (MDV), is a highly contagious lymphoproliferative disease in poultry. Despite the fact that MD h...

A bibliometric analysis of abdominal aortic aneurysm (2014-2024).

BACKGROUND: Abdominal aortic aneurysm (AAA) is a localized bulge of the abdominal aorta, which mainly manifests as a pulsatile mass in the abdomen. On...

Machine learning-based radiomic features of perivascular adipose tissue in coronary computed tomography angiography predicting inflammation status around atherosclerotic plaque: a retrospective cohort study.

OBJECTIVES: This study expolored the relationship between perivascular adipose tissue (PVAT) radiomic features derived from coronary computed tomograp...

Artificial intelligence in emergency neuroradiology: Current applications and perspectives.

Emergency neuroradiology provides rapid diagnostic decision-making and guidance for management for a wide range of acute conditions involving the brai...

3D electron microscopy for analyzing nanoparticles in the tumor endothelium.

Delivering medical agents to diseased tissues has been challenging, leading researchers to study the in vivo transport process in the body for improvi...

Integration of bulk/scRNA-seq and multiple machine learning algorithms identifies PIM1 as a biomarker associated with cuproptosis and ferroptosis in abdominal aortic aneurysm.

BACKGROUND: Abdominal aortic aneurysm (AAA) is a serious life-threatening vascular disease, and its ferroptosis/cuproptosis markers have not yet been ...

Revolutionary drug repositioning: the preventive and therapeutic potential of metformin and other antidiabetic drugs in age-related macular degeneration.

Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly worldwide. Anti-vascular endothelial growth factor (anti-VEGF...

TELEPROM Psoriasis: Enhancing patient-centered care and health-related quality of life (HRQoL) in moderate-to-severe plaque psoriasis.

BACKGROUND AND PURPOSE: Psoriasis is a chronic, immune-mediated inflammatory skin disease that significantly impacts patients' quality of life. The in...

Prediction of Two Year Survival Following Elective Repair of Abdominal Aortic Aneurysms at A Single Centre Using A Random Forest Classification Algorithm.

OBJECTIVE: The decision to electively repair an abdominal aortic aneurysm (AAA) involves balancing the risk of rupture, peri-procedural death, and lif...

Genomic analysis, culturing optimization, and characterization of bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce.

Advances in bacteriophage genome sequencing and regulatory approvals of some bacteriophages in various applications have renewed interest in these ant...

Heparin in sepsis: current clinical findings and possible mechanisms.

Sepsis is a clinical syndrome resulting from the interaction between coagulation, inflammation, immunity and other systems. Coagulation activation is ...

Cell-free plasma telomere length correlated with the risk of cardiovascular events using machine learning classifiers.

This retrospective study explored the association between circulating cell-free plasma telomere length (cf-TL) and coronary artery disease (CAD) and h...