Latest AI and machine learning research in atherosclerosis for healthcare professionals.
Clinical translation of nanomedicines remains constrained by a persistent gap between static preclinical assays and the dynamic shear environment of the human vasculature. This review argues that fluid shear stress is an underappreciated contributor to clinical attrition, acting alongside well-established factors including biomarker-target mismatch, enhanced permeability and retention heterogeneit...
Inflammation contributes to atherosclerosis and vascular remodeling, but the immune pathways associated with distinct carotid ultrasound phenotypes, including carotid intima-media thickness (cIMT), maximal plaque thickness (MPT), and arterial stiffness remain incompletely characterized. We investigated associations between circulating immune biomarkers and carotid ultrasound measures in a stroke-f...
BACKGROUND: The role of the microcirculation in cardiovascular health in males and females is not fully understood. Skin microvascular function can be...
Hypertension and diabetes are major risk factors for heart disease, which remains among the leading causes of morbidity and mortality worldwide. Heart...
BACKGROUND: Older adults with metabolic dysfunction-associated steatotic liver disease have elevated cardiovascular disease (CVD) risk, yet convention...
Individuals with LDL cholesterol (LDL-C) ≥ 190 mg/dL face a markedly increased risk of major adverse cardiovascular events (MACE). Traditional risk ca...
BACKGROUND: Complete revascularisation has been associated with improved short-term outcomes in patients with coronary artery disease, but whether the...
OBJECTIVE: The aim of this study was to develop and validate an anatomy-driven model that predicts gross-total resection (GTR) of skull base chondrosa...
Micro- and nanoplastics (MNPs) have been detected in human renal and urinary tissues and are increasingly recognized as potential environmental contri...
OBJECTIVE: Metabolic syndrome (MetS) is a cluster of metabolic disorders linked to cancer development and progression. The pituitary gland plays a cen...
BACKGROUND: CT angiography (CTA) is a key investigation in cerebrovascular disease. However, CTA is not always available and it also requires intraven...
Cardiorenal syndrome (CRS) describes the bidirectional deterioration of cardiac and renal function, in which dysfunction of one organ induces or perpe...
The population of Vietnam remains underrepresented in global genomic databases. Here, we present VN1K, a resource of multi-omics and phenotypic inform...
OBJECTIVES: To evaluate the reproducibility of quantitative plaque characterization between energy-integrating detector (EID)-CT and photon-counting d...
Keratins (KRTs) are intermediate filament proteins expressed in epithelial cells and serve as diagnostic cancer biomarkers. They serve pivotal roles i...
To evaluate the prognostic significance of nutritional-inflammatory biomarkers in non-small cell lung cancer (NSCLC) patients with bone metastases. Th...
RATIONALE AND OBJECTIVES: To develop and validate the performance and prognostic value of a deep-learning (DL) model for carotid plaque component quan...
Hyperuricemia (HUA) imposes a growing public health burden, calling for better risk stratification tools. In this cross-sectional study of 4906 Chines...
Histological analysis is essential for understanding disease pathology and the microenvironment, particularly in Alzheimer's disease (AD), characteriz...
BACKGROUND: Muscle-invasive bladder cancer (MIBC) is an aggressive and heterogeneous malignancy with limited biomarkers to guide patient stratificatio...