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Bioterrorism

Latest AI and machine learning research in bioterrorism for healthcare professionals.

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When Are Reasoning-Based Guardrails Not Efficient? ResponseGuard: A Fast Vision-Language Guard for Real-Time Moderation

A vision-language AI assistant returns its answer as a stream of generated tokens. Therefore, a safety guard that watches that answer has to keep up with the stream and stop a harmful reply before a user reads it. Recent vision-language guardrails instead generate a chain of thought before they issue a verdict. They believe that step-by-step reasoning yields a safer guard. This design makes the gu...

Jul 23 2026 2607.21401v1

Learning shared forecast-error structure to improve ensemble forecasts of seasonal respiratory outbreaks

Real-time forecasts of seasonal respiratory outbreaks are critical for public health preparedness and healthcare planning. Multi-model ensembles, which combine predictions from individual models, have become a leading approach for operational outbreak forecasting. Their success, however, depends in part on the assumption that component models make sufficiently independent errors. Here, we examined...

The hypoxic response extends lifespan through a bioaminergic and peptidergic neural circuit.

A coordinated response to stress is crucial for promoting the short- and long-term health of an organism. The perception of stress, frequently through...

CAR T cell foundation model predicts immunotherapy response

Single-cell transcriptomics resolves CAR T-cell states, yet translating heterogeneous cellular signals into patient-level therapeutic response remains...

Causal Discovery of Radiation Response Mechanisms in Human Cells

Next-generation sequencing technologies, including RNA-sequencing, provide genome-wide measurements of gene expression and enable broad explorations o...

Jul 15 2026 2607.13994v1
Global co-hotspots of dengue, malaria, and yellow fever: a comparative spatiotemporal analysis across 142 countries

Abstract Dengue, malaria, and yellow fever remain major mosquito-borne public health threats in tropical and subtropical regions. Yet most global spat...

Ecological Cascades and Future Hantavirus Spillover Risk in a Changing Climate

Anthropogenic climate change is reshuffling global biodiversity and accelerating zoonotic spillover at the human-wildlife interface. The 2026 multi-co...

Integrating planetary health and environmental justice into high school construction career education: protocol for a randomized controlled trial of the Ecosystem Justice Translator

Introduction: Climate change disproportionately affects disadvantaged communities, yet construction workforce education rarely addresses interconnecte...

Development and Evaluation of Artificial Intelligence-Assisted Decision Support System for Public Health Emergency Classification and Escalation in Kenya

Background Timely assessment, classification, and escalation of public health events are essential for effective outbreak response, yet decision-makin...

A metacognitive response of the face and the heart in rats

Humans make emotional facial expressions and have a cardiac response when they catch themselves in a mistake or receive feedback about task performanc...

Generative AI Models Reveal Dynamic Views of Aging (DyViA) Phenotypes in Healthy Individuals

Background and objectives: In recent years, the need to develop analytical strategies for healthy aging has assumed great importance. In this study, w...

Predicting Therapeutic Outcome via Aligning Patient-Specific Knowledge Graph and Gene-Level Perturbation Representations

Accurate prediction of patient-specific therapeutic response from pre-treatment transcriptomes is hindered by the scarcity of matched clinical respons...

Jul 6 2026 2607.04557v1
Graph Representation Learning of Longitudinal Medical Imaging Trajectories for Treatment Response Prediction

In patients with breast cancer, pathological complete response (pCR) has been established as a clinically meaningful surrogate marker for long-term ou...

Jul 6 2026 2607.04912v1
TRACE: A Concept Bottleneck Model for Longitudinal 3D Glioblastoma Response Assessment

Longitudinal glioblastoma response assessment requires comparing subtle tumor changes across MRI time points using structured clinical criteria such a...

Jun 29 2026 2606.30313v1
EpiESM-GA: Resource-Efficient Protein Foundation Model Features for Equitable B-Cell Epitope Prediction

Prediction of B-cell epitopes can assist in reducing costly wet-lab screening in vaccine design, diagnostics, and antibody discovery. However, current...

Predicting county-level diagnosed diabetes prevalence in the United States using explainable gradient boosting and geographic interpretation

Diagnosed diabetes affects approximately 38.4 million Americans, but its burden is not evenly distributed across U.S. counties. Existing machine-learn...

Cross-Attention Multimodal Learning for Predicting Response to Neoadjuvant Imatinib in Gastrointestinal Stromal Tumors: A Multicenter Retrospective Study

Background: Response to neoadjuvant imatinib in gastrointestinal stromal tumors (GISTs) is highly variable and cannot be reliably predicted using curr...

Jun 24 2026 2606.25579v1
Inferring and Predicting Clade-Level Relative Transmission Fitness in Seasonal Influenza A Using Differential Population Growth Rate and Deep Learning

Seasonal influenza A evolves rapidly, allowing newly emerged clades to replace previously dominant lineages and complicate surveillance and vaccine ev...

Jun 21 2026 2606.22279v1
Tox21mer, A transformer foundation model for Tox21 high-throughput concentration-response curves data

The U.S. Tox21 collaboration has generated a large reference library of high-throughput concentration-response assays. Here we present Tox21mer, a 43....

A Transformer-derived transcriptomic score associates with ex-vivo drug response in AML

Background Drug-tolerant persister (DTP) cell states have been implicated in relapse across multiple cancers, including acute myeloid leukaemia (AML) ...

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