Psychiatry

Bipolar Disorder

Latest AI and machine learning research in bipolar disorder for healthcare professionals.

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A Quantitative Electrostatic Potential Descriptor Enables Deep Learning-Accelerated Discovery of High-Performance Lithium-Ion Battery Electrolytes.

Rational electrolyte design for high-energy-density lithium-ion batteries (LIBs) urgently demands precise and quantitative molecular descriptors of solvation power to enable deep learning (DL)-accelerated screening, yet such descriptors remain lacking. Here, we introduce the electrostatic potential ratio |ESPmin|/ESPmax (ESPratio) as a quantitative descriptor capturing the balance between electron...

Jul 9 2026 42424155

Machine learning model based on spontaneous brain activity detected by functional MRI for distinguishing unipolar depression from bipolar disorder.

BACKGROUND: The therapeutic strategies for bipolar disorder (BD) and unipolar depression (UD) are quite different. However, the majority of patients with BD often present with a depressive episode as their initial symptom and are misdiagnosed as UD. To date, no reliable tool has been able to accurately differentiate BD patients from UD patients. METHODS: The spontaneous brain activity derived from...

Jul 9 2026 42425243
Baseline metabolic signature predicts cognitive improvement and longitudinal glycerophospholipid shifts track recovery in first-episode drug-naïve schizophrenia.

BACKGROUND: Cognitive impairment is a core yet treatment-resistant feature of schizophrenia (SZ), and reliable biomarkers predicting cognitive improve...

Jul 9 2026 42425477
Predicting Psychiatric Readmission of Children and Adolescents Using Machine Learning.

INTRODUCTION: Recurrent psychiatric hospitalizations in youth are costly and burdensome to patients and families. While postdischarge planning rarely ...

Jul 8 2026 42421253
Neural-network deep potential models for lithium adsorption on C-N-O-modified carbon materials.

Machine-learned interatomic potentials are developed for C-N-O-Li systems that are relevant to lithium-ion battery anode materials. The training datab...

Jul 8 2026 42300628
Machine learning-driven correction of handgrip strength: a novel biomarker for neurological and health outcomes in the UK Biobank.

Handgrip strength (HGS) is a significant biomarker for overall health, offering a simple, cost-effective method for assessing muscle function. Lower H...

Jul 8 2026 42419349
Bioinformatics analysis reveals the characteristics of immune microenvironment in major depressive disorder and vitiligo.

BACKGROUND: Major depressive disorder (MDD) and vitiligo often occur together, worsening patient outcomes. However, the shared pathogenic mechanisms r...

Jul 8 2026 42418414
Capturing omega sign in the clinical assessment of depression by deep learning.

The omega sign is a melancholic facial expression, resembling the Greek letter omega "Ω". To study static omega sign (visible full-blown Ω-shaped or v...

Jul 7 2026 42414259
Ecological assessment of transdiagnostic clinical symptoms in serious mental illness with daily smartphone surveys.

Clinical symptoms in serious mental illness (SMI) fluctuate dynamically, yet standard interview-based assessments are limited in tracking these change...

Jul 6 2026 42409775
Analysis of electrohysterogram signals for predicting obstetric outcome using machine learning methods: a scoping review.

PURPOSE: Efficiently detecting obstetric outcomes, such as preterm birth or mode of delivery, is crucial for enhancing mother and newborn health. Proa...

Jul 6 2026 42410377
Neuroimaging-derived biotypes of self-reported insomnia symptoms are differentially associated with affective symptoms.

BACKGROUND: Sleep problems are among the most prevalent health complaints during adolescence and show a reciprocal relationship with the development o...

Jul 3 2026 42398825
Urinary Volatile Organic Compound Metabolites and Depressive Symptoms Among U.S. Adults With Cardiovascular-Kidney-Metabolic Syndrome Stages 0-3: NHANES-Based Associations and In Silico Multi-Omics Insights.

BACKGROUND: Depression is a major global public health burden, and environmental pollutants are increasingly associated with depressive symptoms. Vola...

Jul 3 2026 42398862
Accelerated brain aging in Veterans with posttraumatic stress symptoms and mild traumatic brain injury.

Exposure to trauma and mild traumatic brain injury (mTBI), which often co-occur and can both trigger acute and chronic pathophysiological processes, h...

Jul 2 2026 42434106
Prediction of Clinically Significant Depressive Symptoms at 2-Year Follow-Up in Older Adults: Machine Learning Study Using the English Longitudinal Study of Ageing.

BACKGROUND: Depression in older adults is often underdiagnosed due to atypical symptom presentation and generational stigma, leading to delayed interv...

Jul 2 2026 42390822
Association of lipid profiles with suicide attempts in young adults with first-episode drug-naive major depressive disorder: a gender-specific analysis.

Major depressive disorder (MDD) is strongly associated with suicide risk. While lipid metabolism dysregulation is implicated in MDD pathophysiology, i...

Jun 30 2026 42380411
A Review of Failure Modes and Safety Strategies of Lithium-Ion Batteries from Materials to Systems.

Lithium-ion batteries (LIBs) have rapidly proliferated due to their high energy density, fast charging capability, and long cycle life. However, intri...

Jun 30 2026 42376912
Esketamine multi-omic biomarker evaluation in major depressive disorder (EMBER-MDD): concept, objectives and methodologies of a non-clinical investigator-initiated study.

Treatment resistance (TR) in major depressive disorder (MDD) affects a substantial minority of patients and is hard to recognize early, delaying inten...

Jun 30 2026 42377483
Therapeutic Interaction Features of AI Chatbots in Depression Interventions: Systematic Review and Meta-Analysis.

BACKGROUND: Depression is a prevalent mental health disorder and a leading cause of disability worldwide, creating substantial personal and societal b...

Jun 30 2026 42379144
Programmable optoelectronic memristors for energy-efficient adaptive binarized spiking neural networks.

Hardware realization of brain-inspired vision critically relies on neuromorphic devices that couple sensing, computation, and adaptive learning, yet s...

Jun 29 2026 42370436
Graph Convolutional Neural Network based Depression Detection using Brain Functional Connectivity Measures.

The structural and functional connectivity of the brain network is a combination of complex connections and interconnections among neurons of differen...

Jun 29 2026 42371895
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