Brain Cancer

A neural controller for online laser power adjustment during the heat therapy process in the presence of nanoparticles.

The present research evaluated the efficiency of a control approach to control the temperature of a breast tumor mass in the presence of nanoparticles exposed to laser radiation. However, if the radiation is carried out in open loop manner it may result in excessive temperature rise healthy cells that exist in the vicinity of tumor's cells. This may lead to the death of healthy cells. So, using cl...

Classification of High-Grade Glioma into Tumor and Nontumor Components Using Support Vector Machine.

BACKGROUND AND PURPOSE: Current imaging assessment of high-grade brain tumors relies on the Response Assessment in Neuro-Oncology criteria, which measure gross volume of enhancing and nonenhancing lesions from conventional MRI sequences. These assessments may fail to reliably distinguish tumor and nontumor. This study aimed to classify enhancing and nonenhancing lesion areas into tumor-versus-nont...

Expert system classifier for adaptive radiation therapy in prostate cancer.

A classifier-based expert system was developed to compare delivered and planned radiation therapy in prostate cancer patients. Its aim is to automatic...

RABiT-II: Implementation of a High-Throughput Micronucleus Biodosimetry Assay on Commercial Biotech Robotic Systems.

We demonstrate the use of high-throughput biodosimetry platforms based on commercial high-throughput/high-content screening robotic systems. The cytok...

Improved image quality with simultaneously reduced radiation exposure: Knowledge-based iterative model reconstruction algorithms for coronary CT angiography in a clinical setting.

BACKGROUND: The aim of this study was to assess the potential for radiation dose reduction using knowledge-based iterative model reconstruction (K-IMR...

A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma.

BACKGROUND: We have identified molecules that exhibit synthetic lethality in cells with loss of the neurofibromin 1 (NF1) tumor suppressor gene. Howev...

Advantages of Synthetic Noise and Machine Learning for Analyzing Radioecological Data Sets.

The ecological effects of accidental or malicious radioactive contamination are insufficiently understood because of the hazards and difficulties asso...

Learning MRI-based classification models for MGMT methylation status prediction in glioblastoma.

BACKGROUND AND OBJECTIVE: The O-methylguanine-DNA-methyltransferase (MGMT) promoter methylation has been shown to be associated with improved outcomes...

F-Choline Positron Emission Tomography/Computed Tomography and Multiparametric Magnetic Resonance Imaging for the Detection of Early Local Recurrence of Prostate Cancer Initially Treated by Radiation Therapy: Comparison With Systematic 3-Dimensional Transperineal Mapping Biopsy.

PURPOSE: To compare the diagnostic performance of F-fluorocholine positron emission tomography/computed tomography (FCH-PET/CT), multiparametric prost...

Evaluation of topical bevacizumab as an adjunct to mitomycin C augmented trabeculectomy.

PURPOSE: To investigate the safety and synergistic effect of topical bevacizumab after trabeculectomy surgery with mitomycin C (MMC).

Impact of robotics and a suspended lead suit on physician radiation exposure during percutaneous coronary intervention.

BACKGROUND: Reports of left-sided brain malignancies among interventional cardiologists have heightened concerns regarding physician radiation exposur...

Enhanced photostability, radical scavenging and antitumor activity of indole-3-carbinol-loaded rose hip oil nanocapsules.

This study aimed to develop poly(ε-caprolactone) nanocapsules loaded with indole-3-cabinol (I3C) using rose hip oil (RHO) or medium chain triglyceride...

Cancer Care Access and Outcomes for American Indian Populations in the United States: Challenges and Models for Progress.

Low socioeconomic and health care access realities of being American Indian/Alaskan Native (AI/AN) in the United States combined with decades of data ...

Exploring Value From the Patient's Perspective Between Modern Radiation Therapy Modalities for Localized Prostate Cancer.

PURPOSE: Patients' perspectives on their treatment experiences have not been compared between modern radiation modalities for localized prostate cance...

U.S. Department of Defense Multiple-Parameter Biodosimetry Network.

The U.S. Department of Defense (USDOD) service members are at risk of exposure to ionizing radiation due to radiation accidents, terrorist attacks and...

A Randomized Phase 2 Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy-Induced Esophagitis During the Treatment of Lung Cancer: Results of NRG Oncology RTOG 1012.

PURPOSE: Randomized trials have shown that honey is effective for the prevention of radiation-induced mucositis in head and neck cancer patients. Beca...

Patterns of Recurrence After Postprostatectomy Fossa Radiation Therapy Identified by C-11 Choline Positron Emission Tomography/Computed Tomography.

PURPOSE: To evaluate C-11 choline positron emission tomography/computed tomography (CholPET) in staging and determining patterns of recurrence in pros...

Multi-atlas and unsupervised learning approach to perirectal space segmentation in CT images.

Perirectal space segmentation in computed tomography images aids in quantifying radiation dose received by healthy tissues and toxicity during the cou...

Growth of Uveal Melanoma following Intravitreal Bevacizumab.

PURPOSE: Typically treatment of large melanomas (by Collaborative Ocular Melanoma Study criteria) is restricted to enucleation, due to size constraint...

Limited short-term effect of palliative radiation therapy on quantitative computed tomography-derived bone mineral density in femora with metastases.

PURPOSE: The aim of this study was to determine the effect of single fraction (SF) and multiple fraction (MF) radiation therapy (RT) on bone mineral d...