Oncology/Hematology

Breast Cancer

Latest AI and machine learning research in breast cancer for healthcare professionals.

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CT4CMS: Preoperative Computed Tomography-Based Consensus Molecular Subtyping Prediction in Colorectal Cancer Using Interpretable Deep Learning

Consensus molecular subtyping (CMS) defines the transcriptomic taxonomy of colorectal cancer (CRC) and guides precision therapy. Although current approaches can predict CMS from histopathology, they rely on surgical specimens, limiting their preoperative applicability. In this study, we developed a deep learning model to infer CMS directly from preoperative computed tomography (CT) scans, enabling...

Longitudinal NSCLC Treatment Progression via Multimodal Generative Models

Predicting tumor evolution during radiotherapy is a clinically critical challenge, particularly when longitudinal changes are driven by both anatomy and treatment. In this work, we introduce a Virtual Treatment (VT) framework that formulates non-small cell lung cancer (NSCLC) progression as a dose-aware multimodal conditional image-to-image translation problem. Given a CT scan, baseline clinical v...

Mar 6 2026 2603.06147v1
AI End-to-End Radiation Treatment Planning Under One Second

Artificial intelligence-based radiation therapy (RT) planning has the potential to reduce planning time and inter-planner variability, improving effic...

Mar 6 2026 2603.06338v1
Deep Learning Enabled 3D Multi-Omic Analysis Reveals Molecular Signatures of Heterogeneous Response to Chemotherapy in Pancreatic Cancer

Resistance to systemic therapy is a major unmet challenge in pancreatic cancer. To identify potential mechanisms of resistance, we developed a novel 3...

RANGER: Sparsely-Gated Mixture-of-Experts with Adaptive Retrieval Re-ranking for Pathology Report Generation

Pathology report generation remains a relatively under-explored downstream task, primarily due to the gigapixel scale and complex morphological hetero...

Mar 4 2026 2603.04348v1
A comprehensive benchmark of publicly available image foundation models for their usability to predict gene expression from whole slide images

Recent advances in large-scale self-supervised learning have led to the emergence of foundation models capable of extracting transferable visual repre...

Transcriptomic profiling of mouse mammary tumors enables prognostic and predictive biomarker discovery for human breast cancers

The development and validation of prognostic and predictive biomarkers in breast cancer is limited by the availability of well-annotated datasets link...

Temporal dynamics of radiotherapy and chemotherapy response in lower-grade gliomas using causal machine learning

Lower-grade gliomas (World Health Organization [WHO] grades 2-3) exhibit variable treatment responses, yet clinical decisions remain guided by populat...

TC-SSA: Token Compression via Semantic Slot Aggregation for Gigapixel Pathology Reasoning

The application of large vision-language models to computational pathology holds great promise for diagnostic assistants but faces a critical computat...

Mar 1 2026 2603.01143v1
The MAMA-MIA Challenge: Advancing Generalizability and Fairness in Breast MRI Tumor Segmentation and Treatment Response Prediction

Breast cancer is the most frequently diagnosed malignancy among women worldwide and a leading cause of cancer-related mortality. Dynamic contrast-enha...

Mar 1 2026 2603.01250v1
Onco-Shikshak: An AI-Native Adaptive Learning Ecosystem for Medical Oncology Education

Medical oncology education faces a dual crisis: knowledge velocity that outpaces static curricula and large language model (LLM) risks hallucination a...

MammoWise: Multi-Model Local RAG Pipeline for Mammography Report Generation

Screening mammography is high volume, time sensitive, and documentation heavy. Radiologists must translate subtle visual findings into consistent BI-R...

Feb 25 2026 2602.22462v1
Momentum Memory for Knowledge Distillation in Computational Pathology

Multimodal learning that integrates genomics and histopathology has shown strong potential in cancer diagnosis, yet its clinical translation is hinder...

Feb 24 2026 2602.21395v1
Benchmarking Transfer Learning for Dense Breast Tissue Segmentation on Small Mammogram Datasets

Dense breast tissue diminishes the sensitivity of mammographic screening and is a key cancer risk factor, which motivates accurate segmentation under ...

Inference of cancer driver mutations from tumor microenvironmentcomposition: a pan-cancer study with cross-platform external validation

Cancer driver mutations shape the tumor microenvironment (TME), yet whether TME composition alone can predict genotype has not been systematically eva...

Survival risk heterogeneity among patients with NSCLC receiving nivolumab visualized by risk scores generated from deep learning method DeepSurv using tumor gene mutations

Immunotherapy with immune checkpoint inhibitors and immunotherapy combined with chemotherapy have represented promising treatments for NSCLC patients ...

LGD-Net: Latent-Guided Dual-Stream Network for HER2 Scoring with Task-Specific Domain Knowledge

It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the...

Feb 19 2026 2602.17793v1
A NOVEL DEEP LEARNING MODEL, RDBCYCYLEGAN-CBAM FOR LOW-DOSE CT IMAGE DENOISING

Computed Tomography (CT) is one of the largest contributors to radiation exposure from medical imaging, which can induce DNA damage and increase cance...

Systematic Evaluation of Transfer Learning Strategies for Clinical Chemotherapy Response Prediction

Accurately predicting chemotherapy response remains a major challenge in precision oncology. Although machine-learning models based on tumour omics da...

A radiation-free screening system for adolescent idiopathic scoliosis using deep learning on 3D back surface point clouds

Widespread screening for Adolescent Idiopathic Scoliosis (AIS) is critical for timely intervention but is currently constrained by the radiation risks...

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