Oncology/Hematology

Breast Cancer

Latest AI and machine learning research in breast cancer for healthcare professionals.

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The Hemodynamic Management and Postoperative Outcomes After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Prospective Observational Study.

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) has become standard treatment for peritoneal cancers and metastases, significantly enhancing survival rates. This study evaluated the relationship between tumor burden, hemodynamic management, and postoperative outcomes after CRS-HIPEC. This study included 203 patients undergoing CRS-HIPEC. The study was registered ...

Dec 27 2024 39760061

Prognostic Impact of Tumor Cell Nuclear Size Assessed by Artificial Intelligence in Esophageal Squamous Cell Carcinoma.

Tumor cell nuclear size (NS) indicates malignant potential in breast cancer; however, its clinical significance in esophageal squamous cell carcinoma (ESCC) is unknown. Artificial intelligence (AI) can quantitatively evaluate histopathological findings. The aim was to measure NS in ESCC using AI and elucidate its clinical significance. We investigated the relationship between NS assessed by AI and...

Dec 26 2024 39732367
Predicting benefit from PARP inhibitors using deep learning on H&E-stained ovarian cancer slides.

PURPOSE: Ovarian cancer patients with a Homologous Recombination Deficiency (HRD) often benefit from polyadenosine diphosphate-ribose polymerase (PARP...

Dec 26 2024 39742559
Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma.

We employed a mechanistic learning approach, integrating on-treatment tumor kinetics (TK) modeling with various machine learning (ML) models to addres...

Dec 25 2024 39722558
A unified deep-learning framework for enhanced patient-specific quality assurance of intensity-modulated radiation therapy plans.

BACKGROUND: Modern radiation therapy techniques, such as intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT), use...

Dec 24 2024 39718209
Automated treatment planning with deep reinforcement learning for head-and-neck (HN) cancer intensity modulated radiation therapy (IMRT).

To develop a deep reinforcement learning (DRL) agent to self-interact with the treatment planning system to automatically generate intensity modulated...

Dec 24 2024 39577088
Automated Measurement of Effective Radiation Dose by F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography.

BACKGROUND/OBJECTIVES: Calculating the radiation dose from CT in F-PET/CT examinations poses a significant challenge. The objective of this study is t...

Dec 23 2024 39728913
CXCL12 impact on glioblastoma cells behaviors under dynamic culture conditions: Insights for developing new therapeutic approaches.

Glioblastoma multiforme (GBM) is the most prevalent malignant brain tumor, with an average survival time of 14 to 20 months. Its capacity to invade br...

Dec 23 2024 39715221
Improving the prediction of chemotherapy dose-limiting toxicity in colon cancer patients using an AI-CT-based 3D body composition of the entire L1-L5 lumbar spine.

PURPOSE: Chemotherapy dose-limiting toxicities (DLT) pose a significant challenge in successful colon cancer treatment. Body composition analysis may ...

Dec 21 2024 39707027
Improving prediction of solar radiation using Cheetah Optimizer and Random Forest.

In the contemporary context of a burgeoning energy crisis, the accurate and dependable prediction of Solar Radiation (SR) has emerged as an indispensa...

Dec 20 2024 39705221
Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer.

BACKGROUND/AIMS: It was recently reported that a higher concentration of the bacterially produced metabolite indole 3-acetate (3-IAA) in blood was lin...

Dec 20 2024 39759130
Artificial Intelligence-Empowered Multistep Integrated Radiation Therapy Workflow for Nasopharyngeal Carcinoma.

PURPOSE: To establish an artificial intelligence (AI)-empowered multistep integrated (MSI) radiation therapy (RT) workflow for patients with nasophary...

Dec 19 2024 39708045
Can knowledge-based planning models validated on ethnically diverse patients lead to global standardisation of external beam radiation therapy for locally advanced cervix cancer?

BACKGROUND AND PURPOSE: Knowledge-based planning (KBP) can consistently and efficiently create high-quality Volumetric Arc Therapy (VMAT) plans for ce...

Dec 19 2024 39709028
Development of two machine learning models to predict conversion from primary HER2-0 breast cancer to HER2-low metastases: a proof-of-concept study.

BACKGROUND: HER2-low expression has gained clinical relevance in breast cancer (BC) due to the availability of anti-HER2 antibody-drug conjugates for ...

Dec 19 2024 39705838
Reduced-dose deep learning iterative reconstruction for abdominal computed tomography with low tube voltage and tube current.

BACKGROUND: The low tube-voltage technique (e.g., 80 kV) can efficiently reduce the radiation dose and increase the contrast enhancement of vascular a...

Dec 18 2024 39696218
Improving the prediction of patient survival with the aid of residual convolutional neural network (ResNet) in colorectal cancer with unresectable liver metastases treated with bevacizumab-based chemotherapy.

BACKGROUND: To verify overall survival predictions made with residual convolutional neural network-determined morphological response (ResNet-MR) in pa...

Dec 18 2024 39696483
Biochemical, Radiographic, or Pathologic Response to Neoadjuvant Chemotherapy in Resected Pancreatic Cancer: Which Is Best?

OBJECTIVE: To examine the optimal method of assessing response to neoadjuvant therapy (NAT) in patients with operable pancreatic ductal adenocarcinoma...

Dec 16 2024 39676639
Artificial intelligence improves mammography-based breast cancer risk prediction.

Artificial intelligence (AI) is enabling us to delve deeply into the information inherent in a mammogram and identify novel features associated with h...

Dec 12 2024 39672755
Stress testing deep learning models for prostate cancer detection on biopsies and surgical specimens.

The presence, location, and extent of prostate cancer is assessed by pathologists using H&E-stained tissue slides. Machine learning approaches can acc...

Dec 11 2024 39660731
Self-improving generative foundation model for synthetic medical image generation and clinical applications.

In many clinical and research settings, the scarcity of high-quality medical imaging datasets has hampered the potential of artificial intelligence (A...

Dec 11 2024 39663467
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