Breast Cancer

Learning deep features for dead and living breast cancer cell classification without staining.

Automated cell classification in cancer biology is a challenging topic in computer vision and machine learning research. Breast cancer is the most common malignancy in women that usually involves phenotypically diverse populations of breast cancer cells and an heterogeneous stroma. In recent years, automated microscopy technologies are allowing the study of live cells over extended periods of time...

Metrics to evaluate the performance of auto-segmentation for radiation treatment planning: A critical review.

Advances in artificial intelligence-based methods have led to the development and publication of numerous systems for auto-segmentation in radiotherapy. These systems have the potential to decrease contour variability, which has been associated with poor clinical outcomes and increased efficiency in the treatment planning workflow. However, there are no uniform standards for evaluating auto-segmen...

Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance.

Resistance to ionizing radiation, a first-line therapy for many cancers, is a major clinical challenge. Personalized prediction of tumor radiosensitiv...

Breast glandularity and mean glandular dose assessment using a deep learning framework: Virtual patients study.

PURPOSE: Breast dosimetry in mammography is an important aspect of radioprotection since women are exposed periodically to ionizing radiation due to b...

A deep learning-based auto-segmentation system for organs-at-risk on whole-body computed tomography images for radiation therapy.

BACKGROUND AND PURPOSE: Delineating organs at risk (OARs) on computed tomography (CT) images is an essential step in radiation therapy; however, it is...

Providing an accurate global model for monthly solar radiation forecasting using artificial intelligence based on air quality index and meteorological data of different cities worldwide.

This study aims to present an exact model for predicting solar radiation worldwide through a general model. In this study, mean monthly global solar r...

A novel multi-DoF surgical robotic system for brachytherapy on liver tumor: Design and control.

PURPOSE: Radioactive seed implantation is an effective invasive treatment method for malignant liver tumors in hepatocellular carcinomas. However, cha...

Improving the therapeutic ratio of radiotherapy against radioresistant cancers: Leveraging on novel artificial intelligence-based approaches for drug combination discovery.

Despite numerous advances in cancer radiotherapy, tumor radioresistance remain one of the major challenges limiting treatment efficacy of radiotherapy...

Internet of medical things embedding deep learning with data augmentation for mammogram density classification.

Females are approximately half of the total population worldwide, and most of them are victims of breast cancer (BC). Computer-aided diagnosis (CAD) f...

Multi-magnification-based machine learning as an ancillary tool for the pathologic assessment of shaved margins for breast carcinoma lumpectomy specimens.

The surgical margin status of breast lumpectomy specimens for invasive carcinoma and ductal carcinoma in situ (DCIS) guides clinical decisions, as pos...

Mask-Guided Convolutional Neural Network for Breast Tumor Prognostic Outcome Prediction on 3D DCE-MR Images.

In this proof-of-concept work, we have developed a 3D-CNN architecture that is guided by the tumor mask for classifying several patient-outcomes in br...

Radiomics analysis on CT images for prediction of radiation-induced kidney damage by machine learning models.

INTRODUCTION: We aimed to assess the power of radiomic features based on computed tomography to predict risk of chronic kidney disease in patients und...

PathoNet introduced as a deep neural network backend for evaluation of Ki-67 and tumor-infiltrating lymphocytes in breast cancer.

The nuclear protein Ki-67 and Tumor infiltrating lymphocytes (TILs) have been introduced as prognostic factors in predicting both tumor progression an...

Oncologic Equipoise Between Robotic and Open Radical Cystectomy.

Our objective was to establish the incidence of positive surgical margins, recurrence patterns, and recurrence-free (RFS) and overall survival (OS) i...

Deep learning reconstruction of digital breast tomosynthesis images for accurate breast density and patient-specific radiation dose estimation.

The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radi...

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning.

The optimization of therapeutic antibodies is time-intensive and resource-demanding, largely because of the low-throughput screening of full-length an...

Impact of image compression on deep learning-based mammogram classification.

Image compression is used in several clinical organizations to help address the overhead associated with medical imaging. These methods reduce file si...

Magnetic tri-bead microrobot assisted near-infrared triggered combined photothermal and chemotherapy of cancer cells.

Magnetic micro/nanorobots attracted much attention in biomedical fields because of their precise movement, manipulation, and targeting abilities. Howe...

Robot-assisted Cystectomy with Intracorporeal Urinary Diversion After Pelvic Irradiation for Prostate Cancer: Technique and Results from a Single High-volume Center.

BACKGROUND: Radiation therapy (RT) for prostate cancer (PCa) treatment is burdened by high rates of late urinary adverse events (UAEs). The feasibilit...

Can artificial intelligence overtake human intelligence on the bumpy road towards glioma therapy?

Gliomas are one of the most devastating primary brain tumors which impose significant management challenges to the clinicians. The aggressive behaviou...