Cardiovascular

Latest AI and machine learning research in cardiovascular for healthcare professionals.

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Computer-aided drug discovery of a dual-target inhibitor for ovarian cancer: therapeutic intervention targeting CDK1/TTK signaling pathway and structural insights in the NCI-60.

Ovarian cancer remains the third most prevalent and deadliest gynecologic malignancy worldwide, with most patients eventually developing resistance to platinum-based chemotherapy. This highlights a critical unmet need for innovative multitargeted therapies to address current treatment challenges. In this study, we identified 35 differentially expressed genes (DEGs) through integrated analysis of f...

Jul 1 2025 40446543

Deep Learning Image Reconstruction (DLIR) Algorithm to Maintain High Image Quality and Diagnostic Accuracy in Quadruple-low CT Angiography of Children with Pulmonary Sequestration: A Case Control Study.

RATIONALE AND OBJECTIVES: CT angiography (CTA) is a commonly used clinical examination to detect abnormal arteries and diagnose pulmonary sequestration (PS). Reducing the radiation dose, contrast medium dosage, and injection pressure in CTA, especially in children, has always been an important research topic, but few research is proven by pathology. The current study aimed to evaluate the diagnost...

Jul 1 2025 40410108
Transforming the management of radiotherapy-induced hypothyroidism in nasopharyngeal carcinoma through an Innovative individualized radiation dosage model: A multicenter retrospective analysis.

PURPOSE: Current guidelines for thyroid radiation dose prescription lack uniformity and fail to consider the unique characteristics of individual pati...

Jul 1 2025 40409363
Machine learning prediction of pathological complete response to neoadjuvant chemotherapy with peritumoral breast tumor ultrasound radiomics: compare with intratumoral radiomics and clinicopathologic predictors.

PURPOSE: Noninvasive, accurate and novel approaches to predict patients who will achieve pathological complete response (pCR) after neoadjuvant chemot...

Jul 1 2025 40377810
RAPTOR-AI: An open-source AI powered radiation protection toolkit for radioisotopes.

Artificial intelligence (AI) has gained significant attention in various scientific fields due to its ability to process large datasets. In nuclear ra...

Jul 1 2025 40184907
Radiomics-based machine learning in prediction of response to neoadjuvant chemotherapy in osteosarcoma: A systematic review and meta-analysis.

BACKGROUND AND AIMS: Osteosarcoma (OS) is the most common primary bone malignancy, and neoadjuvant chemotherapy (NAC) improves survival rates. However...

Jul 1 2025 40349577
MammoTracker: Mask-Guided Lesion Tracking in Temporal Mammograms

Accurate lesion tracking in temporal mammograms is essential for monitoring breast cancer progression and facilitating early diagnosis. However, aut...

HASD: Hierarchical Adaption for pathology Slide-level Domain-shift

Domain shift is a critical problem for pathology AI as pathology data is heavily influenced by center-specific conditions. Current pathology domain ...

Detection of Breast Cancer Lumpectomy Margin with SAM-incorporated Forward-Forward Contrastive Learning

Complete removal of cancer tumors with a negative specimen margin during lumpectomy is essential in reducing breast cancer recurrence. However, 2D s...

[Advances in low-dose cone-beam computed tomography image reconstruction methods based on deep learning].

Cone-beam computed tomography (CBCT) is widely used in dentistry, surgery, radiotherapy and other medical fields. However, repeated CBCT scans expose ...

Jun 25 2025 40566788
Blood-based proteomic profiling identifies OSMR as a novel biomarker of AML outcomes.

Inflammation is increasingly recognized as a critical factor in acute myeloid leukemia (AML) pathogenesis. We performed blood-based proteomic profilin...

Jun 19 2025 40179376
Quantitative and qualitative metrics of tumor stroma in predicting ovarian cancer outcomes and expansion of its study with AI-based tools.

Epithelial ovarian cancer remains one of the deadliest gynecologic malignancies, with late-stage diagnosis, high recurrence rates, and resistance to p...

Jun 18 2025 40524858
Prediction of bacterial and fungal bloodstream infections using machine learning in patients undergoing chemotherapy.

PURPOSE: This study aimed to develop a machine learning (ML) model to predict bloodstream infection (BSI) in chemotherapy patients.

Jun 18 2025 40382858
ViT-NeBLa: A Hybrid Vision Transformer and Neural Beer-Lambert Framework for Single-View 3D Reconstruction of Oral Anatomy from Panoramic Radiographs

Dental diagnosis relies on two primary imaging modalities: panoramic radiographs (PX) providing 2D oral cavity representations, and Cone-Beam Comput...

Nanotechnology-Enhanced siRNA Delivery: Revolutionizing Cancer Therapy.

RNA interference (RNAi) has emerged as a transformative approach for cancer therapy, enabling precise gene silencing through small interfering RNA (si...

Jun 16 2025 40354673
BreastDCEDL: Curating a Comprehensive DCE-MRI Dataset and developing a Transformer Implementation for Breast Cancer Treatment Response Prediction

Breast cancer remains a leading cause of cancer-related mortality worldwide, making early detection and accurate treatment response monitoring criti...

Network Pharmacology Reveals HSPA1A/BST2 as Potential Targets of Ci Bai Capsule's Active Compounds Intervening in Leukopenia

Background: Radiation-induced leukopenia caused by low-dose exposure is frequently associated with Traditional Chinese Medicine (TCM) syndromes like...

Taming Stable Diffusion for Computed Tomography Blind Super-Resolution

High-resolution computed tomography (CT) imaging is essential for medical diagnosis but requires increased radiation exposure, creating a critical t...

Validation and Derivation of miRNA-Based Germline Signatures Predicting Radiation Toxicity in Prostate Cancer.

PURPOSE: Although radiotherapy (RT) is one of the primary treatment modalities used in the treatment of cancer, patients often experience toxicity dur...

Jun 13 2025 40192540
Modality-AGnostic Image Cascade (MAGIC) for Multi-Modality Cardiac Substructure Segmentation

Cardiac substructures are essential in thoracic radiation therapy planning to minimize risk of radiation-induced heart disease. Deep learning (DL) o...

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