Cardiovascular

Latest AI and machine learning research in cardiovascular for healthcare professionals.

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TCUP – An Open Access Tool to Predict Tissue of Origin and Cancer of Unknown Primary (CUP)

Cancer of unknown primary (CUP) remains a major diagnostic hurdle, compromising therapies that depen...

Characterization of metabolic phenotypes in breast cancer through the integration of genome-scale metabolic models and machine learning

The metabolic heterogeneity of breast cancer represents a significant challenge for the identificati...

Translating clinical gene sequencing into a foundational representation of tumor subtype

While gene sequencing is routine in cancer care, translating sequences into treatment decisions rema...

Gene-Family Encoding Boosts Domain-Adapted Single-Cell Language Models

Transformer-based single-cell foundation models often rely on ranked-gene (RG) sequences where genes...

SpliceSelectNet: A Hierarchical Transformer-Based Deep Learning Model for Splice Site Prediction

Accurate RNA splicing is essential for gene expression and protein function, yet the mechanisms gove...

Pathologist-interpretable breast cancer subtyping and stratification from AI-inferred nuclear features

Artificial intelligence (AI) is making notable advances in digital pathology but faces challenges in...

Breast Cancer Subtyping with HyperCLSA: A Hypergraph Contrastive Learning Pipeline for Multi-Omics Data Integration

Accurate molecular subtyping of cancer is crucial for advancing personalized medicine. Although mult...

DREAMER-S: Deep leaRning-Enabled Attention-based Multiple-instance approaches with Explainable Representations for Spatial biology

Identifying image features that associate strongly with diagnostic or prognostic classes in large-sc...

Predicting MammaPrint Recurrence Risk from Breast Cancer Pathological Images Using a Weakly Supervised Transformer

Recurrence related to poor prognosis is a leading cause of mortality in patients with breast cancer ...

Identifying tissue states by spatial protein patterns related to chemotherapy response in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is an aggressive malignancy with limited targeted therapies and...

Single-cell RNA sequencing and large-scale bulk combination with machine learning reveal gastric cancer-related macrophage heterogeneity

The tumor microenvironment (TME) significantly impacts cancer progression and overall patient surviv...

Deep Learning Bridges Histology and Transcriptomics to Predict Molecular Subtypes and Outcomes in Muscle-Invasive Bladder Cancer

Muscle-Invasive Bladder Cancer (MIBC) is a heterogeneous disease with distinct molecular subtypes in...

A machine learning framework for supervised treatment response prediction from tumor transcriptomics: A large-scale pan-cancer study

Precision oncology aims to guide treatment decisions using biomarkers. While DNA-based panels are in...

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