Cardiovascular

Cytotoxic activity of ethyl acetate extract of on MCF7 and T47D breast cancer cells.

One of the most cancers in women that can be fatal is breast cancer. Radiation therapy, chemotherapy, or a combination of the two are often used to treat cancer, and these treatments tend to modify the immune system and weaken defences. Using natural compounds from plants has become a research interest to prevent cancer cell development. The aim of this study was to determine the anticancer activi...

Machine Learning-Based MRI Radiogenomics for Evaluation of Response to Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma.

RATIONALE AND OBJECTIVES: To develop and validate a radiogenomics model integrating clinical data, radiomics-based machine learning (RBML) classifiers, and transcriptomics data for predicting the response to induction chemotherapy (IC) in patients with head and neck squamous cell carcinoma (HNSCC).

Deep learning catheter tip locations for photoacoustic-guided cardiac interventions.

SIGNIFICANCE: Interventional cardiac procedures often require ionizing radiation to guide cardiac catheters to the heart. To reduce the associated ris...

PROACTING: predicting pathological complete response to neoadjuvant chemotherapy in breast cancer from routine diagnostic histopathology biopsies with deep learning.

BACKGROUND: Invasive breast cancer patients are increasingly being treated with neoadjuvant chemotherapy; however, only a fraction of the patients res...

Clinical service evaluation of the feasibility and reproducibility of novel artificial intelligence based-echocardiographic quantification of global longitudinal strain and left ventricular ejection fraction in trastuzumab-treated patients.

INTRODUCTION: Cardiotoxicity is a potential prognostically important complication of certain chemotherapeutic agents that may result in preclinical or...

ASO Author Reflections: Deep-Learning Radiomics Nomogram Based on Enhanced CT to Predict the Effect of Neoadjuvant Chemotherapy on Metastatic Lymph Nodes in Locally Advanced Gastric Cancer.

Deep Learning Radiomics Nomogram Based on Enhanced CT to Predict the Response of Metastatic Lymph Nodes to Neoadjuvant Chemotherapy in Locally Advanced Gastric Cancer.

BACKGROUND: We aimed to construct and validate a deep learning (DL) radiomics nomogram using baseline and restage enhanced computed tomography (CT) im...

Framework for Radiation Oncology Department-wide Evaluation and Implementation of Commercial Artificial Intelligence Autocontouring.

PURPOSE: Artificial intelligence (AI)-based autocontouring in radiation oncology has potential benefits such as standardization and time savings. Howe...

Exploring Capabilities of Large Language Models such as ChatGPT in Radiation Oncology.

PURPOSE: Technological progress of machine learning and natural language processing has led to the development of large language models (LLMs), capabl...

Enhancing Safety in AI-Driven Cone Beam CT-based Online Adaptive Radiation Therapy: Development and Implementation of an Interdisciplinary Workflow.

PURPOSE: The emerging online adaptive radiation therapy (OART) treatment strategy based on cone beam computed tomography allows for real-time replanni...

Development of MRI-Based Deep Learning Signature for Prediction of Axillary Response After NAC in Breast Cancer.

RATIONALE AND OBJECTIVES: To develop a MRI-based deep learning signature for predicting axillary response after neoadjuvant chemotherapy (NAC) in brea...

Current Strengths and Weaknesses of ChatGPT as a Resource for Radiation Oncology Patients and Providers.

PURPOSE: Chat Generative Pre-Trained Transformer (ChatGPT), an artificial intelligence program that uses natural language processing to generate conve...

Screening the phytotoxicity of micro/nanoplastics through non-targeted metallomics with synchrotron radiation X-ray fluorescence and deep learning: Taking micro/nano polyethylene terephthalate as an example.

Microplastics (MPs) and nanoplastics (NPs) are global pollutants with emerging concerns. Methods to predict and screen their toxicity are crucial. Ele...

Healthcare Professional Association Agency in Preparing for Artificial Intelligence: A Multiple-Case Study of Radiation Medicine and Medical Imaging in the Canadian context.

As artificial intelligence (AI) is increasingly integrated in healthcare, it is incumbent on healthcare professional associations (HPAs) to assist the...

Application of statistical machine learning in biomarker selection.

In the recent JAVELIN Bladder 100 phase 3 trial, avelumab plus best supportive care significantly prolonged overall survival relative to best supporti...

Nomograms integrating CT radiomic and deep learning signatures to predict overall survival and progression-free survival in NSCLC patients treated with chemotherapy.

OBJECTIVES: This study aims to establish nomograms to accurately predict the overall survival (OS) and progression-free survival (PFS) in patients wit...

Deep learning to predict breast cancer sentinel lymph node status on INSEMA histological images.

BACKGROUND: Sentinel lymph node (SLN) status is a clinically important prognostic biomarker in breast cancer and is used to guide therapy, especially ...

Artificial Intelligence-Based Organ Delineation for Radiation Treatment Planning of Prostate Cancer on Computed Tomography.

PURPOSE: Meticulous manual delineations of the prostate and the surrounding organs at risk are necessary for prostate cancer radiation therapy to avoi...

Aggregate Formation and Antibody Stability in Infusion Bags: The Impact of Manual and Robotic Compounding of Monoclonal Antibodies.

Monoclonal antibodies (mAbs) can be damaged during the aseptic compounding process, with aggregation being the most prevalent form of degradation. Pro...

Deep learning-assisted high-content screening identifies isoliquiritigenin as an inhibitor of DNA double-strand breaks for preventing doxorubicin-induced cardiotoxicity.

BACKGROUND: Anthracyclines including doxorubicin are essential components of many cancer chemotherapy regimens, but their cardiotoxicity severely limi...