Oncology/Hematology

Chemotherapy

Latest AI and machine learning research in chemotherapy for healthcare professionals.

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Effect of MRP2 and MRP3 Polymorphisms on Anastrozole Glucuronidation and MRP2 and MRP3 Gene Expression in Normal Liver Samples.

Anastrozole is an aromatase inhibitor (AI) used as adjuvant therapy for breast cancer. Anastrozole i...

Predicting Response to Neoadjuvant Chemotherapy with PET Imaging Using Convolutional Neural Networks.

Imaging of cancer with 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) has become ...

Synthesis of -Mannich bases of berberine linking piperazine moieties revealing anticancer and antioxidant effects.

A new Mannich base series of piperazine linked berberine analogues was furnished in this study to sc...

Genomic signatures for paclitaxel and gemcitabine resistance in breast cancer derived by machine learning.

Increasingly, the effectiveness of adjuvant chemotherapy agents for breast cancer has been related t...

Successful radiotherapy in postoperative recurrence of a primary mediastinal yolk sac tumor: A case report.

A woman in her 60s was evaluated for anterior chest pain. Computed tomography (CT) revealed a 50 mm ...

Application of a UPLC-MS/MS method to the protein binding study of TM-2 in rat, human and beagle dog plasma.

TM-2 known as a potential antitumor drug is a novel semi-synthetic taxane derivative. As drug-protei...

CYP19A1 Genetic Polymorphisms rs4646 and Osteoporosis in Patients Treated with Aromatase Inhibitor-Based Adjuvant Therapy.

OBJECTIVE: Third-generation aromatase inhibitors (AI) are potent suppressors of aromatase activity. ...

Multi-class BCGA-ELM based classifier that identifies biomarkers associated with hallmarks of cancer.

BACKGROUND: Traditional cancer treatments have centered on cytotoxic drugs and general purpose chemo...

Clinical evaluation of postoperative chemotherapy based on genetic testing in patients with stage IIIA non-small cell lung cancer.

BACKGROUND: We performed a retrospective analysis to evaluate whether a postoperative chemotherapy s...

Cytotoxic response of platinum-coated gold nanorods in human breast cancer cells at very low exposure levels.

Because of unique optical behavior gold nanorods (GNRs) have attracted attention for the application...

HemOnc.org: A Collaborative Online Knowledge Platform for Oncology Professionals.

PURPOSE: Cancer care involves extensive knowledge about numerous chemotherapy drugs and chemotherapy...

Robotic-assisted pelvic lymph node dissection for prostate cancer: frequency of nodal metastases and oncological outcomes.

PURPOSE: Limited data are available regarding the oncologic efficacy of pelvic lymph node dissection...

IgA nephropathy in systemic lupus erythematosus patients: case report and literature review.

Systemic erythematosus lupus (SLE) is a multisystemic autoimmune disease which has nephritis as one ...

Three- and four-class classification models for P-glycoprotein inhibitors using counter-propagation neural networks.

P-glycoprotein (P-gp) is an ATP binding cassette (ABC) transporter that helps to protect several cer...

Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes.

OBJECTIVE: The purpose of this study was to evaluate the contamination rate of media-fill products e...

Functional outcomes after TORS for oropharyngeal cancer: a systematic review.

Summarize functional outcomes after transoral robotic surgery (TORS) ± adjuvant therapy for orophary...

Outcome of transoral robotic surgery for stage I-II oropharyngeal cancer.

Traditionally T1-2N0 oropharyngeal carcinoma is treated with a single treatment modality, being eith...

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