Chemotherapy

Skeletal Muscle Density as a Predictive Marker for Pathologic Complete Response in Triple-Negative Breast Cancer Treated with Neoadjuvant Chemoimmunotherapy.

: The predictive value of muscle-related indicators in triple-negative breast cancer (TNBC) patients...

Leveraging automated machine learning to predict colon cancer prognosis from clinical features and risk groups: a retrospective cohort study.

BACKGROUND: Predicting colon cancer recurrence is crucial for determining the need for adjuvant ther...

End-to-end prognostication in pancreatic cancer by multimodal deep learning: a retrospective, multicenter study.

OBJECTIVES: Pancreatic cancer treatment plans involving surgery and/or chemotherapy are highly depen...

Leveraging Digital Twins for Stratification of Patients with Breast Cancer and Treatment Optimization in Geriatric Oncology: Multivariate Clustering Analysis.

BACKGROUND: Defining optimal adjuvant therapeutic strategies for older adult patients with breast ca...

Development of Explainable Machine Learning Models to Identify Patients at Risk for 1-Year Mortality and New Distant Metastases Postendoprosthetic Reconstruction for Lower Extremity Bone Tumors: A Secondary Analysis of the PARITY Trial.

BACKGROUND: Accurate prediction of postoperative metastasis and mortality risks in patients undergoi...

Corrigendum to "Ultrasound-Based Deep Learning Radiomics Nomogram for Tumor and Axillary Lymph Node Status Prediction After Neoadjuvant Chemotherapy" [Academic Radiology 32 (2025) 12-23].

External validation of the Oncotype DX breast cancer recurrence score nomogram and development and validation of a novel machine learning-based model to predict postoperative overall survival and guide adjuvant chemotherapy in ER positive, Her-2 negative breast cancer patients: a retrospective cohort study.

BACKGROUND: This study aims to externally validate the performance of the Oncotype DX (ODX) breast c...

Microbial vitamin biosynthesis links gut microbiota dynamics to chemotherapy toxicity.

Dose-limiting toxicities pose a major barrier to cancer treatment. While preclinical studies show th...

Predicting Treatment Outcomes in Glioblastoma: A Risk Score Model for TMZ Resistance and Immune Checkpoint Inhibition.

Glioblastoma (GBM) presents significant therapeutic challenges due to its invasive nature and resist...

Label-Free and Intelligent Cell Death Recognition Toward Lung Cancer Chemotherapy.

The lack of high-throughput, label-free, and intelligent recognition models for assessing cell death...

Machine-guided cell-fate engineering.

The creation of induced pluripotent stem cells (iPSCs) has enabled scientists to explore the functio...

Deep learning predicts HER2 status in invasive breast cancer from multimodal ultrasound and MRI.

The preoperative human epidermal growth factor receptor type 2 (HER2) status of breast cancer is typ...

Construction of Sonosensitizer-Drug Co-Assembly Based on Deep Learning Method.

Drug co-assemblies have attracted extensive attention due to their advantages of easy preparation, a...

A potential new strategy for BC treatment: NPs containing solanine and evaluation of its anticancer and antimetastatic properties.

Solanine has been shown to inhibit cancer by regulating the expression of apoptosis (Bax, Bcl-2) and...

Bioassay-guided isolation of a new cytotoxic compound targeting carbonic anhydrase-II: structure-activity relationships and dynamics studies.

Bioassay-guided isolation of A.J. Scott afforded one new natural product (lupeol butyl ether, ), al...

Dexmedetomidine versus Magnesium Sulphate in Ultrasound-Guided Bilateral bi-Level Erector Spinae Plane Block in Corrective Scoliosis Surgery: A Randomized Controlled Clinical Trial.

OBJECTIVES: There is a scarcity of research regarding the effects of LAs adjuvant drugs in erector s...

Dapagliflozin targets the crosstalk between apoptosis, autophagy, and Hedgehog signaling pathways through AMPK activation in the adjuvant-induced arthritic rat model.

Rheumatoid arthritis is a long-term autoimmune disorder, causes joint capsule, cartilage, and bone d...

Antibacterial and Antibiofilm Activities of Colistin and Ceftazidime-Avibactam Conjugated Silver Nanoparticles.

Multidrug-resistant (MDR) Gram-negative bacteria constitute a major global health concern, and the i...

Lidocaine exhibits antileishmanial and immunomodulatory activities in an in vitro model of tegumentary leishmaniasis.

Local anesthetics have been shown to inhibit or delay the progression of tegumentary leishmaniasis (...

Development of a Transferable Density-Functional Tight-Binding Model for Organic Molecules at the Water/Platinum Interface.

A computationally efficient and transferable approach for modeling reactions at metal/water interfac...

Mitochondrial dysfunction and cell death induced by Toona sinensis leaf extracts through MEK/ERK signaling in glioblastoma cells.

Toona sinensis, a kind of phytochemicals in traditional Chinese medicine widely used in South-East A...