Oncology/Hematology

Chemotherapy

Latest AI and machine learning research in chemotherapy for healthcare professionals.

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The three horizons model applied to medical science.

The three horizons model is a framework that helps manage an organization's innovation strategy. This model considers three aspects (horizons) that should be present in the institution and guide the development of new systems. Applied to medical science, the horizons are considered as paradigms that set the guidelines for clinical knowledge. New technologies can influence this model by causing dis...

Sep 14 2022 36093684

Predictive modelling for high-risk stage II colon cancer using auto-artificial intelligence.

BACKGROUND: Recently, stratification of high-risk stage II colon cancer (CC) and the need for adjuvant chemotherapy have been the focus of attention. The aim of this retrospective study was to define high-risk factors for recurrent stage II CC using Prediction One auto-artificial intelligence (AI) software and develop a new predictive model for high-risk stage II CC.

Aug 28 2022 36031650
Therapy resistance mechanisms in hematological malignancies.

Hematologic malignancies are model diseases for understanding neoplastic transformation and serve as prototypes for developing effective therapies. In...

Aug 23 2022 35962946
mRNAsi-related metabolic risk score model identifies poor prognosis, immunoevasive contexture, and low chemotherapy response in colorectal cancer patients through machine learning.

Colorectal cancer (CRC) is one of the most fatal cancers of the digestive system. Although cancer stem cells and metabolic reprogramming have an impor...

Aug 23 2022 36081499
A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a development and validation study.

BACKGROUND: The DoMore-v1-CRC marker was recently developed using deep learning and conventional haematoxylin and eosin-stained tissue sections, and w...

Aug 11 2022 35964620
Deep learning predicts resistance to neoadjuvant chemotherapy for locally advanced gastric cancer: a multicenter study.

BACKGROUND: Accurate pre-treatment prediction of neoadjuvant chemotherapy (NACT) resistance in patients with locally advanced gastric cancer (LAGC) is...

Aug 6 2022 35932353
Clavien-Dindo classification and risk prediction model of complications after robot-assisted radical hysterectomy for cervical cancer.

Although significant progress has been made with surgical methods, the incidence of complications after minimally invasive surgery in patients with ce...

Aug 1 2022 35913623
Continuously sutured versus linear-stapled anastomosis in robot-assisted hybrid Ivor Lewis esophageal surgery following neoadjuvant chemoradiotherapy: a single-center cohort study.

BACKGROUND: Esophageal cancer surgery is technically highly demanding. During the past decade robot-assisted surgery has successfully been introduced ...

Jul 19 2022 35854126
Predicting recurrence and recurrence-free survival in high-grade endometrial cancer using machine learning.

OBJECTIVE: To develop machine-learning models to predict recurrence and time-to-recurrence in high-grade endometrial cancer (HGEC) following surgery a...

Jul 12 2022 35819161
Histopathologic Basis for a Chest CT Deep Learning Survival Prediction Model in Patients with Lung Adenocarcinoma.

Background A preoperative CT-based deep learning (DL) prediction model was proposed to estimate disease-free survival in patients with resected lung a...

Jul 5 2022 35787198
Combination of CDX2 H-score quantitative analysis with CD3 AI-guided analysis identifies patients with a good prognosis only in stage III colon cancer.

AIM: Stratification of colon cancer (CC) of patients with stage II and III for risk of relapse is still needed especially to drive adjuvant therapy ad...

Jul 1 2022 35785606
Weakly supervised deep learning for prediction of treatment effectiveness on ovarian cancer from histopathology images.

Despite the progress made during the last two decades in the surgery and chemotherapy of ovarian cancer, more than 70 % of advanced patients are with ...

Jun 16 2022 35752000
Autonomous push button-controlled rapid insulin release from a piezoelectrically activated subcutaneous cell implant.

Traceless physical cues are desirable for remote control of the in situ production and real-time dosing of biopharmaceuticals in cell-based therapies....

Jun 15 2022 35704573
Vomiting Management and Effect Prediction after Early Chemotherapy of Lung Cancer with Diffusion-Weighted Imaging under Artificial Intelligence Algorithm and Comfort Care Intervention.

This aim of this research was to explore the evaluation and prediction value of diffusion-weighted imaging (DWI) under artificial intelligence algorit...

Jun 15 2022 35756427
ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function.

Zhenqi Fuzheng formula (ZQFZ), of which the main ingredients are and , has immune system regulatory functions and potential anti-tumor bioactivity. T...

Jun 8 2022 35680568
Nanocatalyst-Enabled Physically Unclonable Functions as Smart Anticounterfeiting Tags with AI-Aided Smartphone Authentication.

Counterfeiting is a worldwide issue affecting many industrial sectors, ranging from specialized technologies to retail market, such as fashion brands,...

May 25 2022 35612325
Deep learning with whole slide images can improve the prognostic risk stratification with stage III colorectal cancer.

BACKGROUND AND OBJECTIVE: Adjuvant chemotherapy is recommended as standard treatment for colorectal cancer (CRC) with stage III according to TNM stage...

May 25 2022 35640390
Computed Tomography Texture Features and Risk Factor Analysis of Postoperative Recurrence of Patients with Advanced Gastric Cancer after Radical Treatment under Artificial Intelligence Algorithm.

Computer tomography texture analysis (CTTA) based on the V-Net convolutional neural network (CNN) algorithm was used to analyze the recurrence of adva...

May 24 2022 35655504
A prediction model for pathological findings after neoadjuvant chemoradiotherapy for resectable locally advanced esophageal squamous cell carcinoma based on endoscopic images using deep learning.

OBJECTIVES: To propose deep-learning (DL)-based predictive model for pathological complete response rate for resectable locally advanced esophageal sq...

May 23 2022 35451338
Calf Thymus Polypeptide Restrains the Growth of Colorectal Tumor Regulating the Intestinal Microbiota-Mediated Immune Function.

Calf thymus polypeptide (CTP), with a molecular mass of <10 kDa, is prepared from the thymus of less than 30-day-old newborn cattle. In the present st...

May 19 2022 35662701
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