Cardiovascular

Congestive Heart Failure

Latest AI and machine learning research in congestive heart failure for healthcare professionals.

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Biomarker and shear stress in secondary pediatric pulmonary hypertension.

Background/aim: Endothelial dysfunction, tissue damage, inflammation, and microthrombosis are involved in the pathogenesis of pulmonary hypertension (PH), which may be present as a complication of congenital heart diseases. This study aims to identify how indicators of endothelial dysfunction (shear stress), tissue damage (brain natriuretic peptide and troponin T), inflammation (C-reactive protein...

Dec 19 2017 29306249

Innovative spectrophotometric methods for simultaneous estimation of the novel two-drug combination: Sacubitril/Valsartan through two manipulation approaches and a comparative statistical study.

Different innovative spectrophotometric methods were introduced for the first time for simultaneous quantification of sacubitril/valsartan in their binary mixture and in their combined dosage form without prior separation through two manipulation approaches. These approaches were developed and based either on two wavelength selection in zero-order absorption spectra namely; dual wavelength method ...

Dec 17 2017 29272807
Mechanisms of pulse pressure amplification dipping pattern during sleep time: the SAFAR study.

The difference in pulse pressure (PP) between peripheral arteries and the aorta, called pulse pressure amplification (PPamp), is a well-described phys...

Dec 14 2017 29287945
The Metabolic Response of Skeletal Muscle to Endurance Exercise Is Modified by the ACE-I/D Gene Polymorphism and Training State.

The insertion/deletion polymorphism in the gene for the regulator of vascular tone, angiotensin-converting enzyme (ACE), is the prototype of a genetic...

Dec 14 2017 29311951
The Effects of Tai Chi Training in Patients with Heart Failure: A Systematic Review and Meta-Analysis.

Heart Failure (HF) is associated with significantly high morbidity and mortality. We performed a meta-analysis and updated new evidences from randomiz...

Dec 7 2017 29375390
l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.

Considering the pathologic importance of metabolic disturbances, advanced glycation end products (AGEs), and chronic inflammation in diabetes mellitus...

Nov 17 2017 29420997
Loculated transudative pleural effusion masquerading as right upper lobe consolidation in a haemodialysis patient.

Pleural effusion is a common encounter in renal failure patients and frequently possess a diagnostic challenge to clinician especially when it was exu...

Oct 18 2017 30263991
DanHong injection targets endothelin receptor type B and angiotensin II receptor type 1 in protection against cardiac hypertrophy.

Cardiac hypertrophy (CH) is an independent risk factor for cardiovascular diseases (CVDs). Mitigating or preventing CH is the most effective strategy ...

Oct 13 2017 29262570
Comparison of hydrocortisone and prednisone in the glucocorticoid replacement therapy post-adrenalectomy of Cushing's Syndrome.

Cushing's syndrome requires glucocorticoid replacement following adrenalectomy. Based on a simplified glucocorticoid therapy scheme and the peri-opera...

Aug 31 2017 29285318
Furosemide ethanol-free oral solutions for paediatric use: formulation, HPLC method and stability study.

BACKGROUND: Oral liquid solutions of the diuretic active ingredient furosemide (FUR) marketed across Europe do not comply with recent requirements for...

Aug 2 2017 31157009
Changes in cardiac function and hemodynamics during robot-assisted laparoscopic prostatectomy with steep head-down tilt: a prospective observational study.

OBJECTIVE: Robot-assisted laparoscopic prostatectomy requires the patient to be placed in a steep head-down tilt. The aim of our study was to investig...

Jul 28 2017 28754145
What Is High Enough? Elevated NT-pro-BNP in Decompensated Paroxysmal Supraventricular Tachycardia.

Since the late 1980s, elevated atrial natriuretic peptide (ANP) was considered the cause of brisk diuresis in adult patients with paroxysmal supravent...

Jun 12 2017 31073468
Machine learning techniques for diabetic macular edema (DME) classification on SD-OCT images.

BACKGROUND: Spectral domain optical coherence tomography (OCT) (SD-OCT) is most widely imaging equipment used in ophthalmology to detect diabetic macu...

Jun 7 2017 28592309
An Implantable Extracardiac Soft Robotic Device for the Failing Heart: Mechanical Coupling and Synchronization.

Soft robotic devices have significant potential for medical device applications that warrant safe synergistic interaction with humans. This article de...

May 30 2017 29182083
Infrastructure and distributed learning methodology for privacy-preserving multi-centric rapid learning health care: euroCAT.

Machine learning applications for personalized medicine are highly dependent on access to sufficient data. For personalized radiation oncology, datase...

May 19 2017 29594204
Robot-assisted thoracoscopic lobectomy as treatment of a giant bulla.

BACKGROUND: A bulla is a marked enlarged space within the parenchyma of the lung. Bullae may cause dyspnea by compressing healthy lung parenchyma and ...

May 18 2017 28521787
A Novel Continuous Blood Pressure Estimation Approach Based on Data Mining Techniques.

Continuous blood pressure (BP) estimation using pulse transit time (PTT) is a promising method for unobtrusive BP measurement. However, the accuracy o...

Apr 28 2017 28463207
Supervised learning and dimension reduction techniques for quantification of retinal fluid in optical coherence tomography images.

PurposeThe purpose of the present study is to develop fast automated quantification of retinal fluid in optical coherence tomography (OCT) image sets....

Apr 21 2017 28430181
Sofosbuvir-based regimens for the treatment of chronic hepatitis C in severe renal dysfunction.

Sofosbuvir (SOF) is a nonstructural 5B polymerase inhibitor with activity in all hepatitis C virus (HCV) genotypes and is the backbone of many anti-HC...

Apr 18 2017 29404457
A machine learning approach to investigate the relationship between shape features and numerically predicted risk of ascending aortic aneurysm.

Geometric features of the aorta are linked to patient risk of rupture in the clinical decision to electively repair an ascending aortic aneurysm (AsAA...

Apr 6 2017 28386685
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