Clinical Trials

The Effectiveness of a Chatbot Single-Session Intervention for People on Waitlists for Eating Disorder Treatment: Randomized Controlled Trial.

BACKGROUND: Early treatment is critical for improving eating disorder prognosis. Single-session inte...

Machine-learning-assisted universal protein activation in living mice.

A universal strategy to precisely control protein activation in living animals is crucial for gain-o...

Strategies to Reduce Hospital Length of Stay: Evidence and Challenges.

Hospital length of stay (HLOS) is a critical healthcare metric influencing patient outcomes, resourc...

In pursuit of software solutions for pharmaceutical regulatory affairs: Insights and trends.

With rapid upsurge in technology and digital tools, the existing systems including the healthcare sy...

Enhancing ERα-targeted compound efficacy in breast cancer threapy with ExplainableAI and GeneticAlgorithm.

Breast cancer remains a major cause of mortality among women globally, driving the need for advanced...

Uncemented hip arthroplasty and denosumab: increased postoperative dipeptide concentrations and identification of potential new bone turnover biomarkers.

Denosumab is a potent antagonist of RANKL and is widely used to treat severe postmenopausal osteopor...

Evaluating the SWIFT algorithm's efficacy in predicting hypoxemia across multiple critical care datasets.

BACKGROUND: Machine learning models to predict hypoxia in patients could improve timely intervention...

Efficacy of using a digital health intervention model using community health workers for primary health services in Bangladesh: a repeated cross-sectional observational study.

OBJECTIVE: This study aims to evaluate the effectiveness of a digital health intervention model by o...

Clinical Validation and Post-Implementation Performance Monitoring of a Neural Network-Assisted Approach for Detecting Chronic Lymphocytic Leukemia Minimal Residual Disease by Flow Cytometry.

: Flow cytometric detection of minimal residual disease (MRD) in chronic lymphocytic leukemia (CLL) ...

Advanced traffic conflict analysis for safety evaluation at roundabouts under mixed traffic using extreme value theory.

Roundabout safety evaluation in non-lane-based, heterogeneous traffic conditions in low-middle-incom...

Use of Virtual Reality in the Pediatric Perioperative Setting and for Induction of Anesthesia: Mixed Methods Pilot Feasibility Study.

BACKGROUND: Children commonly experience high levels of anxiety prior to surgery. This distress is a...

Artificial Intelligence (AI)-Driven Approaches to Manage Postoperative Pain, Anxiety, and Psychological Outcomes in Surgical Patients: A Systematic Review.

Postoperative pain, anxiety, and psychological distress significantly impact surgical recovery, yet ...

Stromal vascular fraction in canine osteoarthritis: advantages, applications, and insights for veterinary practitioners.

Canine osteoarthritis (OA) stands as a prevalent and excruciating joint condition that represents a ...

Deciphering the Immunomodulatory Function of GSN Inflammatory Cancer-Associated Fibroblasts in Renal Cell Carcinoma Immunotherapy: Insights From Pan-Cancer Single-Cell Landscape and Spatial Transcriptomics Analysis.

The heterogeneity of cancer-associated fibroblasts (CAFs) could affect the response to immune checkp...

From error to prevention of wrong-level spine surgery: a review.

Wrong-level spine surgery remains a significant concern in spine surgery, leading to devastating con...

Leveraging Artificial Intelligence to Advance Health Equity in America's Safety Net.

Direct evaluation of antiplatelet therapy in coronary artery disease by comprehensive image-based profiling of circulating platelets.

Coronary artery disease (CAD) is a leading cause of death globally. Antiplatelet therapy remains cru...

Evaluating efficacy of 0.125% atropine using a myopia progression machine learning model.

PURPOSE: To investigate the usefulness of a machine learning (ML) model that can predict the natural...

Estimation of patient safety culture in private and public hospitals using machine learning methods.

BackgroundPatient safety is a critical component of health care systems. Large groups of patients, a...

Efficacy of laryngeal mask epinephrine in neonatal resuscitation; an ovine study.

BACKGROUND: The efficacy of Laryngeal Mask Airway (LMA) epinephrine during neonatal resuscitation ha...

Dexmedetomidine versus Magnesium Sulphate in Ultrasound-Guided Bilateral bi-Level Erector Spinae Plane Block in Corrective Scoliosis Surgery: A Randomized Controlled Clinical Trial.

OBJECTIVES: There is a scarcity of research regarding the effects of LAs adjuvant drugs in erector s...