Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Predicting future cognitive impairment in preclinical Alzheimer’s disease using multimodal imaging: a multisite machine learning study

Predicting the likelihood of developing Alzheimer’s disease (AD) dementia in at-risk individuals is ...

Clinical Usability of Generative Artificial Intelligence for MR Safety Advice

This study investigated whether readily available, generative AI models, could be used to answer MR ...

First-in-Human Study of a First-in-Class AI-Designed Monoclonal Antibody (GB-0669) Against the Conserved SARS-CoV-2 Spike S2 Stem Helix

Antibodies against the SARS-CoV-2 spike receptor-binding domain provided effective COVID-19 treatmen...

Prospective Evaluation of AI Risk Stratification for Triaging Expedited Screening Mammogram Interpretation

To prospectively evaluate the feasibility and performance of expedited screening mammogram interpret...

Understanding the Relationship Between Germ Layer Origin and Cancer Therapy Response: A Systematic Review

Cancer therapeutic response patterns may be fundamentally influenced by embryonic germ layer origin....

The Cognitive Safety Net: Comparing Human and AI Diagnostic Reasoning during Complex Clinical Situations

Diagnostic error in high-stakes clinical environments remains a significant cause of preventable har...

Evaluating an LLM-Assisted Workflow for Clinical Documentation: A Pilot Randomized Controlled Trial on Time and Quality

Large language models (LLMs) have been investigated for clinical documentation, with concerns about ...

PregMedNet: Multifaceted Maternal Medication Impacts on Neonatal Complications

While medication use is common among pregnant women, medication safety remains insufficiently charac...

Beyond Accuracy: An Efficiency- and Safety-Aware Framework for Evaluating Clinical AI with Large Language Models

Large language models (LLMs) demonstrate strong performance on medical reasoning tasks, but current ...

Machine Learning Analysis of Routine EEG Accurately Predicts Anti-Seizure Medication Response

Despite the availability of more than 20 anti-seizure medications (ASMs), approximately half of pati...

Oxytocin Enhances Social-Emotional Reciprocity in Autism

We evaluated whether oxytocin improves social-emotional reciprocity in children and adolescents with...

Leveraging simulation to provide a practical framework for assessing the novel scope of risk of LLMs in healthcare

Large language models (LLMs) are rapidly entering clinical care, yet their definitionally probabilis...

Automated Video-Based Analysis of Surgical Meta-competencies Using Computer Vision

Traditional surgical training relies on an apprenticeship model, which is subjective and threatened ...

Topological Entropy and Homology Reveal Interpretable and Real-Time Neural Signatures in Pediatric EEG

Decoding neural states from pediatric EEG in naturalistic settings remains challenging due to signal...

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