Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Showing 261-280 of 6,112 articles

Optimizing Treatment Strategies in the Bipolar Disorder Spectrum With Classical AI Approaches: Systematic Review of Performance, Bias, and Clinical Applicability.

BACKGROUND: Bipolar disorder (BD) is a complex and heterogeneous psychiatric condition, characterized by fluctuating clinical courses that affect approximately 1%-2% of the global population in their lifetime. Despite pharmacological advances, treatment response varies significantly among patients, making the identification of individualized treatment strategies a major challenge. Artificial Intel...

Jul 21 2026 42479879

Multiturn Large Language Model-Based Conversational Agents for Patients With Cancer and Caregivers: Scoping Review.

BACKGROUND: Large language model (LLM)-based conversational agents are increasingly used in health care, yet their capacity to support genuine multiturn dialogue remains underexplored. In oncology, where patients and caregivers experience complex informational and emotional needs throughout the disease trajectory, conversational agents may support information provision, symptom consultation, and e...

Jul 21 2026 42479903
The backfiring effect of weak AI safety regulation.

Recent policy proposals aim to improve the safety of general-purpose AI, but there is little understanding of the efficacy of different regulatory app...

Jul 20 2026 42475556
Fibrillarin-mediated 2'-O-methylation serves as a translation brake on uncapped enterovirus RNA.

2'-O-methylation (Nm) is a key epitranscriptomic mark across diverse RNAs, yet its role in antiviral defense remains largely unexplored. To systematic...

Jul 20 2026 42475391
Video-Algorithmic Patient Monitoring in Mental Health Inpatient Settings: Qualitative Study of Patient or Consumer, Clinician, and Vendor Perspectives.

BACKGROUND: Video-algorithmic patient monitoring (VAPM) combines remote, noncontact sensors and algorithmic analysis and is increasingly trialed in ac...

Jul 20 2026 42475737
The mediating effect of self-efficacy on the relationship between digital literacy and artificial intelligence anxiety in nursing students.

OBJECTIVE: The integration of digital technologies and artificial intelligence (AI) into healthcare has transformed nursing education, while also rais...

Jul 20 2026 42477725
[Overview and conclusions of the STROKE data platform of the National Laboratory for Translational Neuroscience and the associated clinical studies].

Acute ischemic and hemorrhagic stroke are among the leading causes of mortality and long-term disability worldwide. In addition to the results of rand...

Jul 19 2026 42472441
FKBP10 may affect the malignant phenotype of oral squamous cell carcinoma cells through the ECM/WNT signaling pathway.

Oral squamous cell carcinoma (OSCC) is a common malignant tumor in the oral and maxillofacial region with a poor prognosis, and its pathophysiology ha...

Jul 18 2026 42471471
DB-IRES: a deep learning model based on ensemble learning for predicting internal ribosome entry sites.

BACKGROUND: Internal ribosome entry sites (IRES) are cap-independent translation initiation elements present in specific viral and cellular mRNAs. The...

Jul 18 2026 42471547
Stage-specific predictors of exercise adherence after percutaneous coronary intervention: a prospective multicenter study.

BACKGROUND: The efficacy of exercise after Percutaneous Coronary Intervention (PCI) is compromised by poor long-term adherence. Although multiple infl...

Jul 18 2026 42471567
Associations of employment status with social media addiction, anxiety, and parenting self-efficacy among mothers of infants: a cross-sectional study using machine learning.

BACKGROUND: Differences in social media addiction, anxiety, and parenting self-efficacy according to maternal employment status have important implica...

Jul 18 2026 42469713
Recent developments in the therapeutic management of acid-related gastrointestinal diseases.

INTRODUCTION: Acid-related gastrointestinal diseases, particularly gastroesophageal reflux disease (GERD) and peptic ulcer disease (PUD), remain major...

Jul 17 2026 42470089
Artificial Intelligence Across the Vaccine Clinical Trial Lifecycle: Evidence, Readiness, and Guardrails.

Artificial intelligence (AI) is increasingly being used to support clinical research, but its value in vaccine clinical trials requires careful eviden...

Jul 17 2026 42464875
Quality by Design to Mitigate Aggregation: Mechanistic Insights and Analytical Strategies for Biopharmaceutical Manufacturing.

This review highlights the problem of protein molecule aggregation, which represents a significant challenge in the field of biopharmaceuticals. Prote...

Jul 17 2026 42467318
AI-SOFA: An EMR-integrated Nursing Informatics-driven Decision Support System for Mortality Risk-informed ICU Clinical Decision-making.

Accurate and timely mortality prediction is essential for nursing clinical decision-making in intensive care units (ICUs). Although the Sequential Org...

Jul 17 2026 42467996
Deployment process for artificial intelligence applications in radiology practice.

Successful deployment of medical artificial intelligence (AI) systems should start with formulating clear goals and understanding organisational workf...

Jul 17 2026 42468491
Clinical applications of artificial intelligence in hypertension management: current evidence and future perspectives.

BACKGROUND: Hypertension remains the leading modifiable risk factor for cardiovascular morbidity and mortality worldwide, with persistently inadequate...

Jul 17 2026 42469487
When leaders back the bots: AI affordances, empowerment, and developer innovative work behavior.

As AI-assisted coding, debugging, and code review tools become integrated into the software development workflow, a key question is raised: under what...

Jul 16 2026 42462493
Development of the nursing artificial intelligence readiness scale for nursing students: a validity and reliability study.

BACKGROUND: The rapid integration of artificial intelligence (AI) into healthcare has amplified the need for nurses who can engage with AI-supported s...

Jul 16 2026 42464259
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