Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Showing 301-320 of 6,112 articles

Precision-Driven Management of Great Saphenous Varicose Veins: A Narrative Review.

OBJECTIVES: Great saphenous vein (GSV) incompetence is common, but numerous treatment options complicate patient-treatment matching. This narrative review synthesizes evidence for major treatment modalities and presents a clinically actionable decision framework integrating clinical, anatomical, and patient-specific factors for precision therapy selection. METHODS: A comprehensive literature searc...

Jul 15 2026 42456969

Scientific evidence of commercial artificial intelligence products for pulmonary nodule assessment on CT scans: a systematic review.

OBJECTIVES: This systematic review evaluates the available evidence on the efficacy of commercially available AI-software applications for lung nodule assessment on CT scans. MATERIALS AND METHODS: In adherence to PRISMA guidelines, a thorough search of electronic databases was conducted (January 2012-November 2024) to identify studies on CE-marked and/or FDA-cleared AI-based systems for evaluatin...

Jul 15 2026 42448899
Transcranial photobiomodulation improves prefrontal oxygenation and impulse control in adults with ADHD: a randomized controlled trial.

BACKGROUND: Impulsivity in individuals with attention-deficit/hyperactivity disorder (ADHD) diminishes quality of life. Cortical hypometabolism has be...

Jul 14 2026 42449279
Randomized, Double-Blind, Placebo-Controlled First-in-Human Trial of a First-in-Class AI-Designed Monoclonal Antibody (GB-0669) Against the Conserved SARS-CoV-2 Spike S2 Stem Helix.

BACKGROUND: Antibodies against the SARS-CoV-2 spike receptor-binding domain provided effective COVID-19 treatment until resistant variants emerged. GB...

Jul 14 2026 42446369
Nonverbal AI-Based Communication Robot for Staff in Disaster-Affected Care Facilities: Exploratory ABAB Intervention Study.

BACKGROUND: Medical and welfare facilities in the Noto region of Japan were severely affected by the 2024 Noto Peninsula earthquake and subsequent tor...

Jul 14 2026 42447466
Use of an AI Image Recognition-Based Smartphone App in Personalized Bowel Preparation Before Colonoscopy: Prospective Randomized Controlled Trial.

BACKGROUND: Sufficient bowel preparation is critical for increasing the quality of colonoscopy. However, current bowel preparation guidelines have lim...

Jul 14 2026 42447478
AI-Generated Microlearning for Plastic Surgery Residency: Single-Arm Pre-Post Feasibility Study.

BACKGROUND: Surgical residency training faces mounting pressure from expanding subspecialty knowledge requirements alongside compressed learning oppor...

Jul 14 2026 42447483
An Interactive Virtual Nephrologist to Engage Patients With Advanced CKD About Transplantation.

RATIONALE & OBJECTIVE: Despite advantages in survival and quality of life with kidney transplantation (KT) compared to other treatments for kidney fai...

Jul 14 2026 42448023
Qualitative investigation into the rural and coastal workforce for allied health professional leaders in England.

BACKGROUND: Allied Health Professional (AHP) services in England assess, diagnose, treat and rehabilitate patients across a wide range of health and c...

Jul 14 2026 42448459
Safety boundary maintenance in consumer AI systems responding to pediatric health queries: a cross-platform benchmark evaluation under naturalistic and adversarially pressured conditions.

Consumer artificial intelligence chatbots are now accessed by hundreds of millions of users seeking health information, yet systematic evaluation of t...

Jul 14 2026 42448823
Comparative Evaluation of Locally Delivered Aloe vera Gel as an Adjunct to Scaling and Root Planing in Patients With Periodontitis: A Randomized Clinical Trial.

BACKGROUND: Herbal adjuncts have gained increasing interest in nonsurgical periodontal therapy because of their anti-inflammatory, antimicrobial, and ...

Jul 14 2026 42453492
Perithyroidal Adipose Tissue Drives Thyroid Tumorigenesis through Adipokine Signaling and Immune Suppression.

The perithyroidal adipose tissue (PAT), given its direct anatomical proximity to the thyroid gland, has long been postulated as a modulator of the thy...

Jul 14 2026 42453940
AI meets sleep surgery: assessing drug-induced sleep endoscopy interpretation with a large language model.

STUDY OBJECTIVES: To evaluate the performance and safety of a large language model in interpreting drug-induced sleep endoscopy (DISE) videos and prov...

Jul 13 2026 41134279
An AI-Assisted Tool to Predict Continuous Glucose Monitor Adherence in Children With Type 1 Diabetes in Oman: Protocol for a Multiphase Mixed Methods Translational Study.

BACKGROUND: Type 1 diabetes mellitus (T1DM) in children requires sustained self-management to achieve glycemic targets. Continuous glucose monitoring ...

Jul 13 2026 42348754
How Digital Health Technologies have been Used to Support Regulatory Drug Approval.

OBJECTIVE: The integration of Digital Health Technologies (DHTs) in clinical trials enhances patient recruitment, streamlines data collection, and pro...

Jul 13 2026 42440213
What Counts as Educational Innovation in Clinical Anatomy?

Clinical anatomy has become a prominent setting for educational innovation because it links anatomical science with diagnostic imaging, procedural pra...

Jul 13 2026 42440272
Disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis after failure of biologic or targeted synthetic therapy: a systematic review and network meta-analysis.

RATIONALE: After inadequate response to first-line biologic or targeted synthetic (b/ts) disease-modifying antirheumatic drug (DMARD) therapy in adult...

Jul 13 2026 42440279
AI-Assisted Chest X-Ray Interpretation in Resource-Limited Settings: LuAna Stepped-Wedge Trial Protocol.

BACKGROUND: Artificial intelligence (AI) has the potential to transform chest radiography interpretation by enhancing diagnostic accuracy, identifying...

Jul 13 2026 42441741
Pharmacologic and expectancy effects in depression: Associations with inter-network resting-state connectivity.

Depression involves dysregulation across large-scale neural networks, yet substantial heterogeneity in resting-state functional connectivity (rsFC) ac...

Jul 13 2026 42442664
Machine learning-enabled behavioural and psychological symptoms of dementia management intervention for dementia caregivers: protocol for a hybrid factorial SMART-MRT trial.

BACKGROUND: Behavioural and psychological symptoms of dementia (BPSD) affect over 90% of people living with dementia and are a major contributor to st...

Jul 13 2026 42443790
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