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Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Machine learning: An effective tool for monitoring and ensuring food safety, quality, and nutrition.

The domains of food safety, quality, and nutrition are inundated with complex datasets. Machine learning (ML) has emerged as a powerful tool in food science, offering fast, accessible, and effective solutions compared with conventional methods. This review outlines the applications of ML in safeguarding food safety, enhancing quality, and unraveling nutrition intricacies. The review encompasses th...

Jun 15 2025 40010186

Pushing the Limits of Safety: A Technical Report on the ATLAS Challenge 2025

Multimodal Large Language Models (MLLMs) have enabled transformative advancements across diverse applications but remain susceptible to safety threats, especially jailbreak attacks that induce harmful outputs. To systematically evaluate and improve their safety, we organized the Adversarial Testing & Large-model Alignment Safety Grand Challenge (ATLAS) 2025}. This technical report presents findi...

Conditional Average Treatment Effect Estimation Under Hidden Confounders

One of the major challenges in estimating conditional potential outcomes and conditional average treatment effects (CATE) is the presence of hidden ...

Evaluation of machine-learning models to measure individualized treatment effects from randomized clinical trial data with time-to-event outcomes

In randomized clinical trials, regression models can be used to explore the relationships between patients' variables (e.g., clinical, pathological ...

Artificial Intelligence and Machine Learning in the Development of Vaccines and Immunotherapeutics Yesterday, Today, and Tomorrow

In the past, the development of vaccines and immunotherapeutics relied heavily on trial-and-error experimentation and extensive in vivo testing, oft...

Automated Treatment Planning for Interstitial HDR Brachytherapy for Locally Advanced Cervical Cancer using Deep Reinforcement Learning

High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual...

Malicious LLM-Based Conversational AI Makes Users Reveal Personal Information

LLM-based Conversational AIs (CAIs), also known as GenAI chatbots, like ChatGPT, are increasingly used across various domains, but they pose privacy...

Beyond True or False: Retrieval-Augmented Hierarchical Analysis of Nuanced Claims

Claims made by individuals or entities are oftentimes nuanced and cannot be clearly labeled as entirely "true" or "false" -- as is frequently the ca...

DAVSP: Safety Alignment for Large Vision-Language Models via Deep Aligned Visual Safety Prompt

Large Vision-Language Models (LVLMs) have achieved impressive progress across various applications but remain vulnerable to malicious queries that e...

CrosswalkNet: An Optimized Deep Learning Framework for Pedestrian Crosswalk Detection in Aerial Images with High-Performance Computing

With the increasing availability of aerial and satellite imagery, deep learning presents significant potential for transportation asset management, ...

Prompt to Protection: A Comparative Study of Multimodal LLMs in Construction Hazard Recognition

The recent emergence of multimodal large language models (LLMs) has introduced new opportunities for improving visual hazard recognition on construc...

DriveSuprim: Towards Precise Trajectory Selection for End-to-End Planning

In complex driving environments, autonomous vehicles must navigate safely. Relying on a single predicted path, as in regression-based approaches, us...

Unintended Harms of Value-Aligned LLMs: Psychological and Empirical Insights

The application scope of Large Language Models (LLMs) continues to expand, leading to increasing interest in personalized LLMs that align with human...

HoliSafe: Holistic Safety Benchmarking and Modeling with Safety Meta Token for Vision-Language Model

Despite emerging efforts to enhance the safety of Vision-Language Models (VLMs), current approaches face two main shortcomings. 1) Existing safety-t...

HoliSafe: Holistic Safety Benchmarking and Modeling with Safety Meta Token for Vision-Language Model

Despite emerging efforts to enhance the safety of Vision-Language Models (VLMs), current approaches face two main shortcomings. 1) Existing safety-t...

PRJ: Perception-Retrieval-Judgement for Generated Images

The rapid progress of generative AI has enabled remarkable creative capabilities, yet it also raises urgent concerns regarding the safety of AI-gene...

Trustworthy Medical Question Answering: An Evaluation-Centric Survey

Trustworthiness in healthcare question-answering (QA) systems is important for ensuring patient safety, clinical effectiveness, and user confidence....

Medical World Model: Generative Simulation of Tumor Evolution for Treatment Planning

Providing effective treatment and making informed clinical decisions are essential goals of modern medicine and clinical care. We are interested in ...

From Street Views to Urban Science: Discovering Road Safety Factors with Multimodal Large Language Models

Urban and transportation research has long sought to uncover statistically meaningful relationships between key variables and societal outcomes such...

MTCMB: A Multi-Task Benchmark Framework for Evaluating LLMs on Knowledge, Reasoning, and Safety in Traditional Chinese Medicine

Traditional Chinese Medicine (TCM) is a holistic medical system with millennia of accumulated clinical experience, playing a vital role in global he...

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