Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Next-Level Prediction of Structural Progression in Knee Osteoarthritis: A Perspective.

Osteoarthritis (OA) is a prevalent and disabling chronic disease, with knee OA being the most common form, affecting approximately 73% of individuals over 55 years. Traditional clinical assessments often fail to predict knee structural progression accurately, highlighting the need for improved prognostic methods. This perspective explores the complexity of stratifying knee OA patients based on rap...

May 15 2025 40429891

Controlled Intervention Study on Effects of an AI-Based App to Support Wound Care: First Results.

The KIADEKU project combines datascience and the clinical expertise of wound experts to develop and evaluate an AI-application for incontinence-associated-dermatitis (IAD) and pressure ulcer (PU) wound care. The evaluation study is a controlled, non-randomized clinical trial that investigates the effects of the AI-based system on wound care time, guideline adherence and the task load of the nurse,...

May 15 2025 40380711
An oral norovirus vaccine generates mucosal immunity and reduces viral shedding in a phase 2 placebo-controlled challenge study.

There are currently no licensed vaccines for norovirus, a leading cause of epidemic and endemic gastroenteritis worldwide. Clinical advancement of pro...

May 14 2025 40367195
Intelligent Road Anomaly Detection with Real-time Notification System for Enhanced Road Safety

This study aims to improve transportation safety, especially traffic safety. Road damage anomalies such as potholes and cracks have emerged as a sig...

TrialMatchAI: An End-to-End AI-powered Clinical Trial Recommendation System to Streamline Patient-to-Trial Matching

Patient recruitment remains a major bottleneck in clinical trials, calling for scalable and automated solutions. We present TrialMatchAI, an AI-powe...

Learning Treatment Allocations with Risk Control Under Partial Identifiability

Learning beneficial treatment allocations for a patient population is an important problem in precision medicine. Many treatments come with adverse ...

Current Trends and Future Directions in Lumbar Spine Surgery: A Review of Emerging Techniques and Evolving Management Paradigms.

: Lumbar spine surgery has undergone significant technological transformation in recent years, driven by the goals of minimizing invasiveness, improvi...

May 13 2025 40429385
Prescriptive Predictors of Mindfulness Ecological Momentary Intervention for Social Anxiety Disorder: Machine Learning Analysis of Randomized Controlled Trial Data.

BACKGROUND: Shame and stigma often prevent individuals with social anxiety disorder (SAD) from seeking and attending costly and time-intensive psychot...

May 13 2025 40359509
Optimized SVR with nature-inspired algorithms for environmental modelling of mycotoxins in food virtual-water samples.

The accurate determination of mycotoxins in food samples is crucial to guarantee food safety and minimize their toxic effects on human and animal heal...

May 13 2025 40360653
Supervised machine learning for predicting drug release from acetalated dextran nanofibers.

Electrospun drug-loaded polymeric nanofibers can improve the efficacy of therapeutics for a variety of implications. By design, these biomaterial plat...

May 13 2025 40237176
Active Learning-Based Prediction of Drug Combination Efficacy.

Combination therapy, which involves the use of multiple drugs, has emerged as a promising approach to cancer treatment. However, traditional combinati...

May 13 2025 40304271
Benchmarking Ethical and Safety Risks of Healthcare LLMs in China-Toward Systemic Governance under Healthy China 2030

Large Language Models (LLMs) are poised to transform healthcare under China's Healthy China 2030 initiative, yet they introduce new ethical and pati...

Metrics that matter: Evaluating image quality metrics for medical image generation

Evaluating generative models for synthetic medical imaging is crucial yet challenging, especially given the high standards of fidelity, anatomical a...

Application of Metaheuristics for Optimizing Predictive Models in iHealth: A Case Study on Hypotension Prediction in Dialysis Patients.

Intradialytic hypotension (IDH) is a critical complication in patients with chronic kidney disease undergoing dialysis, affecting both patient safety ...

May 12 2025 40422144
Managing online employer reviews: An impression management perspective for talent recruitment.

The powerful effects of electronic word of mouth on employer branding and prehire outcomes suggest a need for employers to formulate effective respons...

May 12 2025 40354255
The Rise of Clinical Decision Support Algorithms in Pain Management 2009-2024.

This paper examines the rise of clinical decision support algorithms used to assess risk in pain management and the opioid industry's influence on the...

May 12 2025 40355787
User-Centered Methods in Explainable AI Development for Hospital Clinical Decision Support: A Scoping Review.

Explainable Artificial Intelligence (XAI) offers promising advancements in enhancing transparency and usability of AI-based Clinical Decision Support ...

May 12 2025 40357594
Lead Informed Artificial Intelligence Mining of Antitubercular Host Defense Peptides.

Identifying host defense peptides (HDPs) that are effective against drug-resistant infections is challenging due to their vast sequence space. Artific...

May 12 2025 40310992
TokenProber: Jailbreaking Text-to-image Models via Fine-grained Word Impact Analysis

Text-to-image (T2I) models have significantly advanced in producing high-quality images. However, such models have the ability to generate images co...

Predicting Surgical Safety Margins in Osteosarcoma Knee Resections: An Unsupervised Approach

According to the Pan American Health Organization, the number of cancer cases in Latin America was estimated at 4.2 million in 2022 and is projected...

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