Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Prompt Framing and Evidence Requirements for AI-Generated Educational Responses in Dental Education: An Experimental Study.

BACKGROUND: Large language models (LLMs) are increasingly used in health professions education; however, the role of prompt design in shaping their outputs remains poorly understood in clinical training contexts. In dentistry, where the presentation of information, perceived credibility, and procedural reasoning are important, the effects of instructional framing and evidence requirements on artif...

Jul 12 2026 42437519

Machine Learning-Based PAT Tool for Real-Time Residual Moisture Monitoring in Lyophilized Biopharmaceuticals Using NIR Spectroscopy.

There is a growing demand in the pharmaceutical industry to optimize analytical methodologies, reducing time and resource consumption while ensuring rapid process development and cost-efficient manufacturing. Indeed, Food and Drug Administration (FDA) introduced the Process Analytical Technology (PAT) as an initiative enabling manufacturers to measure and control in real-time processes based on th...

Jul 12 2026 42437520
Precision therapeutics and innovative clinical trial design in neurodegenerative diseases.

Neurodegenerative diseases are biologically heterogeneous disorders characterized by progressive neuronal dysfunction, overlapping molecular pathologi...

Jul 11 2026 42435587
Application Effectiveness Analysis of Artificial Intelligence-assisted Teaching in Standardized Training for Medical Imaging Residents.

RATIONALE AND OBJECTIVES: This study evaluated the efficacy of a combined artificial intelligence (AI)-assisted and traditional teaching model in enha...

Jul 11 2026 42436060
Integrating untargeted metabolomics and machine learning to reveal an aberration of sphingolipid metabolism in cardiometabolic HFpEF.

BACKGROUND: Cardiometabolic heart failure with preserved ejection fraction (HFpEF) is a high-risk phenotype primarily driven by metabolic syndrome, wi...

Jul 11 2026 42436519
A cross-sectional evaluation of Large Language Model answers to dental questions.

BACKGROUND: Patients increasingly turn to the Internet and, more recently, to Large Language Models (LLMs) to seek answers to dental questions. Howeve...

Jul 11 2026 42432645
Yin-Huang-Qing-Fei-Capsule derived diosgenin and its optimized nanoconjugate target STAT3 against pulmonary fibrosis.

BACKGROUND: Pulmonary fibrosis (PF) is a progressive, fatal interstitial lung disease with limited curative therapeutic options. Yin-Huang-Qing-Fei (Y...

Jul 10 2026 42497519
Applications of Large Language Models in Ovarian Cancer Management: Protocol for a Systematic Review and Meta-Analysis.

BACKGROUND: Ovarian cancer (OC) is a highly fatal gynecologic malignancy with complex management challenges and limited long-term survival for advance...

Jul 10 2026 42430510
Artificial Intelligence for Evidence Synthesis of Emerging Biologics to Improve Skeletal Health in Osteogenesis Imperfecta: Systematic Review and Meta-Analysis.

BACKGROUND: Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by bone fragility and recurrent fractures. Emerging biologics demons...

Jul 10 2026 42430720
Antibody-drug conjugates in selected solid tumours: a position statement update based on findings from the third workshop held by the ETOP IBCSG Partners Foundation.

The European Thoracic Oncology Platform (ETOP) International Breast Cancer Study Group (IBCSG) Partners Foundation initiated a series of workshops for...

Jul 10 2026 42431135
PregMedNet: Multifaceted maternal medication impacts on neonatal complications.

While medication use is common among pregnant women, medication safety remains insufficiently characterized because studies in pregnant women are chal...

Jul 10 2026 42431892
Development and validation of an AI-driven multimodal system for assessing aerobic gymnastics training using video analysis, motion capture, and physiological signals.

This research developed and validated a comprehensive multimodal assessment system integrating artificial intelligence for aerobic gymnastics training...

Jul 10 2026 42432117
Interpretable coal mine fault detection via orthogonal Kolmogorov-Arnold networks.

The continuous monitoring of safety within underground coal mines generates multivariate sensor data of high dimensionality, posing substantial challe...

Jul 10 2026 42432133
Chatbot Use by Patients Seeking Urogynecologic Consultation: A Randomized Trial.

IMPORTANCE: Urogynecology patients increasingly investigate their problems using technology-based resources, yet the effect of artificial intelligence...

Jul 10 2026 42425711
Nursing Leadership for Digital NICU Transformation: A Systematic Review of Strategies, Digital Health Integration, and Outcomes in High-Risk Neonates.

BACKGROUND: Digital health technologies are increasingly embedded in Neonatal Intensive Care Units (NICUs), yet the role of nurse-led governance in sh...

Jul 10 2026 42437296
Effects of a generative AI-assisted ADPIE Framework on critical thinking, learning self-efficacy, and clinical reasoning in nursing education: a quasi-experimental study.

BACKGROUND: The nursing process is a systematic, patient-centered framework essential for clinical reasoning and decision-making in nursing education....

Jul 9 2026 42426758
Epigenetic editing approaches maturity: AI-driven precision design, delivery innovation, and the road to clinical translation.

Epigenetic editing achieves durable gene silencing through targeted modification of chromatin and DNA methylation states without altering the genomic ...

Jul 9 2026 42421085
Trustworthy AI for personalized glycemic control: a systematic review and critical appraisal of multimodal forecasting and safety-critical closed-loop control.

Tight glycemic control reduces acute complications (hypoglycemia, hyperglycemia) and long-term microvascular/macrovascular risks. The application of A...

Jul 9 2026 42424005
Effectiveness of Humanized AI Avatars and Messenger Gender for Dental Postprocedure Instructions: Two Randomized Experiments.

BACKGROUND: Postcare instructions play a vital role in preventive health care. Traditionally, information on post-dental procedure care is provided th...

Jul 9 2026 42424627
Multidisciplinary research priorities for artificial intelligence in mental health: a call to action.

The use of artificial intelligence (AI) is anticipated to transform mental health care. However, the rapid research growth in this field has outpaced ...

Jul 9 2026 42425118
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